Publications by authors named "Matthew D Zammit"

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The tau biomarker cascade is condensed in Down syndrome compared to sporadic Alzheimer's disease.
Matthew D Zammit, Hailey Bruzzone, Karly A Cody, Jacob Morse, Rachael Wilson

Brain· November 2025

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Lifestyle Composite and Resilience to Alzheimer's Disease Pathology in Down Syndrome.
Emily K Schworer, Matthew D Zammit, Benjamin L Handen, Brianna Piro-Gambetti, Melissa R Jenkins

J Appl Res Intellect Disabil· July 2025

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A head-to-head comparison of multiple amyloid PET radiotracers for Down syndrome clinical trials.
Matthew D Zammit, Julie C Price, Bradley T Christian, Michael S Rafii,

medRxiv· March 2025

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Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study.
Emily K Schworer, Matthew D Zammit, Jiebiao Wang, Benjamin L Handen, Tobey Betthauser

Lancet Neurol· December 2024

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Amyloid age and tau PET timeline to symptomatic Alzheimer's disease in Down syndrome.
Emily K Schworer, Matthew D Zammit, Jiebiao Wang, Benjamin L Handen, Tobey Betthauser

medRxiv· August 2024

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Characterizing brain tau and cognitive decline along the amyloid timeline in Alzheimer's disease.
Karly A Cody, Rebecca E Langhough, Matthew D Zammit, Lindsay Clark, Nathaniel Chin

Brain· June 2024

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Evaluating the effect of extra-cerebral off-target binding in [F-18]MK6240 PET scans in early-stage Alzheimer's disease.
Andrew McVea, Alexandra DiFilippo, Max J McLachlan, Matthew D Zammit, Barbara Bendlin

Imaging Neurosci (Camb)· April 2024

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Characterizing the emergence of amyloid and tau burden in Down syndrome.
Matthew D Zammit, Tobey J Betthauser, Andrew K McVea, Charles M Laymon, Dana L Tudorascu

Alzheimers Dement· January 2024

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White matter microstructure associations to amyloid burden in adults with Down syndrome.
Austin M Bazydlo, Matthew D Zammit, Minjie Wu, Patrick J Lao, Douglas C Dean

Neuroimage Clin· March 2022

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Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome.
Matthew D Zammit, Dana L Tudorascu, Charles M Laymon, Sigan L Hartley, Paul A Ellison

Neuroimage Clin· September 2021

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Corrigendum: Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer's Disease.
Jose L Martinez, Matthew D Zammit, Nicole R West, Bradley T Christian, Anita Bhattacharyya

Front Aging Neurosci· August 2021

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Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer's Disease.
Jose L Martinez, Matthew D Zammit, Nicole R West, Bradley T Christian, Anita Bhattacharyya

Front Aging Neurosci· July 2021

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PET measurement of longitudinal amyloid load identifies the earliest stages of amyloid-beta accumulation during Alzheimer's disease progression in Down syndrome.
Matthew D Zammit, Dana L Tudorascu, Charles M Laymon, Sigan L Hartley, Shahid H Zaman

Neuroimage· March 2021

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Patterns of glucose hypometabolism in Down syndrome resemble sporadic Alzheimer's disease except for the putamen.
Matthew D Zammit, Charles M Laymon, Dana L Tudorascu, Sigan L Hartley, Brianna Piro-Gambetti

Alzheimers Dement (Amst)· January 2021

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Association of sleep with cognition and beta amyloid accumulation in adults with Down syndrome.
Karly A Cody, Brianna Piro-Gambetti, Matthew D Zammit, Bradley T Christian, Benjamin L Handen

Neurobiol Aging· September 2020

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Cognitive indicators of transition to preclinical and prodromal stages of Alzheimer's disease in Down syndrome.
Sigan L Hartley, Benjamin L Handen, Darlynne Devenny, Dana Tudorascu, Brianna Piro-Gambetti, Matthew D Zammit

Alzheimers Dement (Amst)· September 2020

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Amyloid accumulation in Down syndrome measured with amyloid load.
Matthew D Zammit, Charles M Laymon, Tobey J Betthauser, Karly A Cody, Dana L Tudorascu

Alzheimers Dement (Amst)· April 2020

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In Vivo Characterization and Quantification of Neurofibrillary Tau PET Radioligand F-MK-6240 in Humans from Alzheimer Disease Dementia to Young Controls.
Tobey J Betthauser, Karly A Cody, Matthew D Zammit, Dhanabalan Murali, Alexander K Converse

J Nucl Med· January 2019

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