Publications by authors named "Matthew Ewles"

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Observations from a decade of oligonucleotide bioanalysis by LC-MS.
Matthew Ewles, Aaron R Ledvina, Brendan Powers, C Eric Thomas

Bioanalysis· August 2024

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High-sensitivity workflow for LC-MS-based analysis of GalNAc-conjugated oligonucleotides: a case study.
Aaron R Ledvina, Matthew Ewles, Paul Severin, David Good, Cecilia Arfvidsson

Bioanalysis· September 2021

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Whole blood stability in quantitative bioanalysis.
Aaron R Ledvina, Matthew Ewles, Yongle Pang, Stephanie Cape

Bioanalysis· October 2019

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Determination of osimertinib in human plasma, urine and cerebrospinal fluid.
Richard Mitchell, Christopher Bailey, Matthew Ewles, Gordon Swan, Phillip Turpin

Bioanalysis· May 2019

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LC-MS/MS strategies for therapeutic antibodies and investigation into the quantitative impact of antidrug-antibodies.
Matthew Ewles, Ranbir Mannu, Chris Fox, Johannes Stanta, Graeme Evans

Bioanalysis· December 2016

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Quantification of oligonucleotides by LC-MS/MS: the challenges of quantifying a phosphorothioate oligonucleotide and multiple metabolites.
Matthew Ewles, Lee Goodwin, Anneliese Schneider, Tanja Rothhammer-Hampl

Bioanalysis· February 2014

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Case studies: the impact of nonanalyte components on LC-MS/MS-based bioanalysis: strategies for identifying and overcoming matrix effects.
Fumin Li, Matthew Ewles, Mary Pelzer, Theodore Brus, Aaron Ledvina

Bioanalysis· October 2013

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Development of a bioanalytical method for quantification of a 15-mer oligonucleotide at sub-ng/ml concentrations using LC-MS/MS.
Martyn Hemsley, Matthew Ewles, Lee Goodwin

Bioanalysis· June 2012

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Validation of a bioanalytical method for the quantification of a therapeutic peptide, ramoplanin, in human dried blood spots using LC-MS/MS.
Matthew F Ewles, Phillip E Turpin, Lee Goodwin, David M Bakes

Biomed Chromatogr· September 2011

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Bioanalytical approaches to analyzing peptides and proteins by LC--MS/MS.
Matthew Ewles, Lee Goodwin

Bioanalysis· June 2011

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