Publications by authors named "Matthew Flick"

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Depletion of Fibrinogen Suppresses Growth of Primary Tumors and Metastasis of Pancreatic Ductal Adenocarcinoma.
Nayela N Chowdhury, Dana K Mitchell, Kadri Kangro, Kierra Eldridge, Sara Abrahams, Matthew J Flick

Gastroenterology· December 2025

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Factor XIII: driving (cross-)links in hemostasis, thrombosis, and disease.
James P Luyendyk, Matthew J Flick, Alisa S Wolberg

Blood· September 2025

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Plasminogen activation and plasmin activity are not necessary to prevent venous thrombosis/thromboembolism.
Yaqiu Sang, Marzia Menegatti, Jennifer A Brody, Kerri L Wiggins, Brian C Cooley, Matthew J Flick

Blood· September 2025

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Rastafarianism: When Religious Beliefs Conflict With Medical Necessity-A Case Report and Review of the Literature Around an Ethically Complicated Case.
Matthew Flick, Casey Martinez, David C Fipps

Case Rep Psychiatry· March 2025

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Targeting uPAR with an antibody-drug conjugate suppresses tumor growth and reshapes the immune landscape in pancreatic cancer models.
Virginia Metrangolo, Michaela Hansen Blomquist, Ananya Dutta, Henrik Gårdsvoll, Oliver Krigslund, Matthew J Flick

Sci Adv· January 2025

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Fighting fibrin with fibrin: Vancomycin delivery into coagulase-mediated Staphylococcus aureus biofilms via fibrin-based nanoparticle binding.
Grant Scull, Adrian Aligwekwe, Ysabel Rey, Drew Koch, Kimberly Nellenbach, Matthew J Flick

J Biomed Mater Res A· December 2024

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Suppressing upregulation of fibrinogen after polytrauma mitigates thrombosis in mice.
Monica S Seadler, Francesca Ferraresso, Muskan Bansal, Amber Haugen, William G Hayssen, Matthew J Flick

J Trauma Acute Care Surg· December 2024

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Hepatocyte-independent PAR1-biased signaling controls liver pathology in experimental obesity.
Holly Cline, Zimu Wei, Dafna J Groeneveld, Jeremy M L Hix, Xiao Xu, Matthew J Flick

J Thromb Haemost· November 2024

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Activated platelets retain and protect most of their factor XIII-A cargo from proteolytic activation and degradation.
Yaqiu Sang, Robert H Lee, Annie Luong, Éva Katona, Claire S Whyte, Matthew J Flick

Blood Adv· October 2024

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Regulation of hepatic inclusions and fibrinogen biogenesis by SEL1L-HRD1 ERAD.
Zhenfeng Song, Pattaraporn Thepsuwan, Woosuk Steve Hur, Mauricio Torres, Shuangcheng Alivia Wu, Matthew James Flick

Nat Commun· October 2024

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4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse hemostasis model.
Abigail Ballard-Kordeliski, Robert H Lee, Ellen C O'Shaughnessy, Paul Y Kim, Summer R Jones, Matthew J Flick

Blood· September 2024

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The catheterized bladder environment induces dysregulation of macrophage polarization exacerbating bacterial UTI.
Armando M Marrufo, Jonathan J Molina, Chris Gager, Marissa J Andersen, Alyssa A LaBella, Matthew J Flick

bioRxiv· July 2024

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Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI.
Jonathan J Molina, Kurt N Kohler, Christopher Gager, Marissa J Andersen, Ellsa Wongso, Matthew J Flick

Nat Commun· March 2024

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Coagulation and platelet biology at the intersection of health and disease: illustrated capsules of the 11th Symposium on Hemostasis at the University of North Carolina.
Maria Aleman, Gowthami M Arepally, Trevor Baglin, Lorena Buitrago, Pavel Davizon-Castillo, Matthew J Flick

Res Pract Thromb Haemost· March 2024

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Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A.
Amy W Strilchuk, Woosuk S Hur, Paul Batty, Yaqiu Sang, Sara R Abrahams, Matthew J Flick

Sci Transl Med· February 2024

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Mice expressing nonpolymerizable fibrinogen have reduced arterial and venous thrombosis with preserved hemostasis.
Woosuk S Hur, Tomohiro Kawano, Jean Marie N Mwiza, David S Paul, Robert H Lee, Matthew J Flick

Blood· January 2024

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Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression.
Nayela N Chowdhury, Yi Yang, Ananya Dutta, Michelle Luo, Zimu Wei, Matthew J Flick

Mol Oncol· January 2024

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Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures.
Leland S Hu, Fulvio D'Angelo, Taylor M Weiskittel, Francesca P Caruso, Shannon P Fortin Ensign, Matthew J Flick

Nat Commun· September 2023

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Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI.
Jonathan J Molina, Kurt N Kohler, Christopher Gager, Marissa J Andersen, Ellsa Wongso, Matthew J Flick

Res Sq· September 2023

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Fibrinogen γ' promotes host survival during Staphylococcus aureus septicemia in mice.
Oscar Negrón, Miranda Weggeman, Jos Grimbergen, Emily G Clark, Sara Abrahams, Matthew J Flick

J Thromb Haemost· August 2023

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Altered fibrinogen γ-chain cross-linking in mutant fibrinogen-γ mice drives acute liver injury.
Lauren G Poole, Lauren R Schmitt, Anthony Schulte, Dafna J Groeneveld, Holly M Cline, Matthew J Flick

J Thromb Haemost· August 2023

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Protease-activated receptors and glycoprotein VI cooperatively drive the platelet component in thromboelastography.
Tanvi Rudran, Silvio Antoniak, Matthew J Flick, Mark H Ginsberg, Alisa S Wolberg

J Thromb Haemost· August 2023

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4D intravital imaging studies identify platelets as the predominant cellular procoagulant surface in a mouse model of hemostasis.
Abigail Ballard-Kordeliski, Robert H Lee, Ellen C O'Shaughnessy, Paul Y Kim, Summer Jones, Matthew J Flick

bioRxiv· August 2023

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Citrullination of α2-antiplasmin is unlikely to contribute to enhanced plasmin generation in COVID-19 pathophysiology.
Kadri Kangro, Robert A Campbell, Ronak Tilvawala, Matthew J Flick, Alisa S Wolberg

Res Pract Thromb Haemost· August 2023

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Novel genetic regulators of fibrinogen synthesis identified by an in vitro experimental platform.
Dre'Von A Dobson, Lori A Holle, Feng-Chang Lin, Jennifer E Huffman, James P Luyendyk, Matthew J Flick

J Thromb Haemost· March 2023

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