Publications by authors named "Matthew J Locke"

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A pathway toward clinical translation of hyperpolarized [1,4-C,2,3-d]fumarate as an imaging biomarker for early cellular necrosis in vivo.
Jonathan R Birchall, Pascal Wodtke, Ashley Grimmer, Esben S S Hansen, Lotte B Bertelsen, Matthew J Locke

Magn Reson Med· September 2025

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Measuring cerebral enzymatic activity, brain pH and extracranial muscle metabolism with hyperpolarized C-pyruvate.
Alixander S Khan, Mary A McLean, Joshua D Kaggie, Ines Horvat-Menih, Tomasz Matys, Matthew J Locke

NMR Biomed· December 2024

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Multiarm, non-randomised, single-centre feasibility study-investigation of the differential biology between benign and malignant renal masses using advanced magnetic resonance imaging techniques (IBM-Renal): protocol.
Ines Horvat-Menih, Mary A McLean, Maria Jesus Zamora-Morales, Marta Wylot, Joshua Kaggie, Matthew J Locke

BMJ Open· October 2024

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Deuterium metabolic imaging and hyperpolarized C-MRI of the normal human brain at clinical field strength reveals differential cerebral metabolism.
Joshua D Kaggie, Alixander S Khan, Tomasz Matys, Rolf F Schulte, Matthew J Locke

Neuroimage· August 2022

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Author Correction: Hyperpolarised C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer.
Nikita Sushentsev, Mary A McLean, Anne Y Warren, Arnold J V Benjamin, Cara Brodie, Matthew J Locke

Nat Commun· March 2022

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Hyperpolarized C-Pyruvate Metabolism as a Surrogate for Tumor Grade and Poor Outcome in Renal Cell Carcinoma-A Proof of Principle Study.
Stephan Ursprung, Ramona Woitek, Mary A McLean, Andrew N Priest, Mireia Crispin-Ortuzar, Matthew J Locke

Cancers (Basel)· January 2022

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Hyperpolarised C-MRI identifies the emergence of a glycolytic cell population within intermediate-risk human prostate cancer.
Nikita Sushentsev, Mary A McLean, Anne Y Warren, Arnold J V Benjamin, Cara Brodie, Matthew J Locke

Nat Commun· January 2022

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Hyperpolarized Carbon-13 MRI for Early Response Assessment of Neoadjuvant Chemotherapy in Breast Cancer Patients.
Ramona Woitek, Mary A McLean, Stephan Ursprung, Oscar M Rueda, Raquel Manzano Garcia, Matthew J Locke

Cancer Res· December 2021

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