Publications by authors named "Matthew Jacobson"

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A structure-based tool to interpret the significance of kinase mutations in clinical next generation sequencing in cancer.
Amith Rangarajan, Ilona Sviezhentseva, Emma Gunderson, Yana Pikman, Matthew P Jacobson

Front Oncol· September 2025

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Hybrid GPU Monte Carlo software toolkit for fast and accurate cone-beam CT simulation.
Jericho O'Connell, Matthew Jacobson, Thomas Harris, Raphael Bruegger, Dianne Ferguson

Med Phys· August 2025

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Characterization and Clinical Translation of a Novel Prototype Kilovoltage Dual-Layer Imager for Onboard Imaging.
Thomas C Harris, Matthew Jacobson, Raphael Bruegger, Vera Birrer, Dianne Ferguson

Int J Radiat Oncol Biol Phys· August 2025

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A role for pH dynamics regulating transcription factor DNA-binding selectivity.
Kyle P Kisor, Diego Garrido Ruiz, Matthew P Jacobson, Diane L Barber

Nucleic Acids Res· May 2025

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The Climatic Resilience of the Sasanian Empire.
Matthew J Jacobson, Alison L Gascoigne, Dominik Fleitmann

Hum Ecol Interdiscip J· January 2025

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Consequences of Pore Polarity and Solvent Structure on Epoxide Ring-Opening in Lewis and Brønsted Acid Zeolites.
David S Potts, Jessica K Komar, Matthew A Jacobson, Huston Locht, David W Flaherty

JACS Au· September 2024

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BCR::ABL1 kinase N-lobe mutants confer moderate to high degrees of resistance to asciminib.
Ariel Leyte-Vidal, Diego Garrido Ruiz, RosaAnna DeFilippis, Inga B Leske, Delphine Rea, Matthew P Jacobson

Blood· August 2024

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Identifying FUS amyotrophic lateral sclerosis disease signatures in patient dermal fibroblasts.
Karl Kumbier, Maike Roth, Zizheng Li, Julia Lazzari-Dean, Christopher Waters, Matthew P Jacobson

Dev Cell· August 2024

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A role for pH dynamics regulating transcription factor DNA binding selectivity.
Kyle P Kisor, Diego Garrido Ruiz, Matthew P Jacobson, Diane L Barber

bioRxiv· May 2024

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A kV-MV approach to CBCT metal artifact reduction using multi-layer MV-CBCT.
Matthew W Jacobson, Tom Harris, Marios Myronakis, Mathias Lehmann, Pascal Huber

Phys Med Biol· March 2024

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MV-based relative electron density estimation (iMREDe) for MR-LINAC dose calculation.
Marios Myronakis, Yue-Houng Hu, Matthew William Jacobson, Christopher Leigh Williams, Ross Isaac Berbeco

Med Phys· March 2024

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Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.
Jonathan Paolino, Boris Dimitrov, Beth Apsel Winger, Angelica Sandoval-Perez, Amith Vikram Rangarajan, Matthew P Jacobson

Clin Cancer Res· November 2023

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Monte Carlo model of a prototype flat-panel detector for multi-energy applications in radiotherapy.
Ikechi Ozoemelam, Marios Myronakis, Thomas C Harris, Pablo Corral Arroyo, Pascal Huber, Matthew W Jacobson

Med Phys· October 2023

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Signal peptide mimicry primes Sec61 for client-selective inhibition.
Shahid Rehan, Dale Tranter, Phillip P Sharp, Gregory B Craven, Eric Lowe, Matthew P Jacobson

Nat Chem Biol· September 2023

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Searching for molecular hypoxia sensors among oxygen-dependent enzymes.
Li Li, Susan Shen, Philip Bickler, Matthew P Jacobson, Lani F Wu

Elife· July 2023

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Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases.
Paul J Sampognaro, Shruti Arya, Giselle M Knudsen, Emma L Gunderson, Angelica Sandoval-Perez, Matthew P Jacobson

Mol Neurodegener· May 2023

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Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity.
Capria Rinaldi, Christopher S Waters, Zizheng Li, Karl Kumbier, Lee Rao, Matthew P Jacobson

Cell Rep· May 2023

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Correction: Mutations in α-synuclein, TDP-43 and tau prolong protein half-life through diminished degradation by lysosomal proteases.
Paul J Sampognaro, Shruti Arya, Giselle M Knudsen, Emma L Gunderson, Angelica Sandoval-Perez, Matthew P Jacobson

Mol Neurodegener· May 2023

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Correction to "Assessing the Activation of Tyrosine Kinase KIT through Free Energy Calculations".
Angélica Sandoval-Pérez, Beth Apsel Winger, Matthew P Jacobson

J Chem Theory Comput· January 2023

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Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues.
Wilian A Cortopassi, Emma Gunderson, Yasmin Annunciato, Antony E S Silva, Amália Dos Santos Ferreira, Matthew P Jacobson

Int J Parasitol Drugs Drug Resist· December 2022

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Cysteine Oxidation in Proteins: Structure, Biophysics, and Simulation.
Diego Garrido Ruiz, Angelica Sandoval-Perez, Amith Vikram Rangarajan, Emma L Gunderson, Matthew P Jacobson

Biochemistry· October 2022

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Assessing the Activation of Tyrosine Kinase KIT through Free Energy Calculations.
Angélica Sandoval-Pérez, Beth Apsel Winger, Matthew P Jacobson

J Chem Theory Comput· October 2022

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Structure-based discovery of nonopioid analgesics acting through the α-adrenergic receptor.
Elissa A Fink, Jun Xu, Harald Hübner, Joao M Braz, Philipp Seemann, Matthew P Jacobson

Science· September 2022

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Droughts and societal change: The environmental context for the emergence of Islam in late Antique Arabia.
Dominik Fleitmann, John Haldon, Raymond S Bradley, Stephen J Burns, Hai Cheng, Matthew Jacobson

Science· June 2022

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Settlement, environment, and climate change in SW Anatolia: Dynamics of regional variation and the end of Antiquity.
Matthew J Jacobson, Jordan Pickett, Alison L Gascoigne, Dominik Fleitmann, Hugh Elton

PLoS One· June 2022

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