Publications by authors named "Matthew L Hirsch"

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Adeno-associated vector corneal gene therapy reverses corneal clouding in a feline model of mucopolysaccharidosis VI.
Brian C Gilger, Liujiang Song, Tomoko Hasegawa, Jacklyn H Salmon, Jacquelyn J Bower, Matthew L Hirsch

PLoS One· December 2025

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Allele-specific depletion of via siRNA or an rAAV2-shRNA vector induces selective toxicity in uveal melanoma cells.
Trace F McCall, Emma J Sawyer, Joshua Darnell, Matthew L Hirsch, Jacquelyn J Bower

Mol Ther Oncol· September 2025

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AAV vector transduction restriction and attenuated toxicity in hESCs via a rationally designed inverted terminal repeat.
Liujiang Song, Tomoko Hasegawa, Nolan J Brown, Jacquelyn J Bower, Richard J Samulski, Matthew L Hirsch

Nucleic Acids Res· January 2025

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Ocular toxicity, distribution, and shedding of intravitreal AAV-eqIL-10 in horses.
Kim Young, Tomoko Hasegawa, Naveen Vridhachalam, Nichol Henderson, Jacklyn H Salmon, Matthew L Hirsch

Mol Ther Methods Clin Dev· December 2024

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A chimeric anti-vascularization immunomodulator prevents high-risk corneal transplantation rejection via ex vivo gene therapy.
Brian C Gilger, Tomoko Hasegawa, R Bryan Sutton, Jacquelyn J Bower, Chengwen Li, Matthew L Hirsch

Mol Ther· November 2024

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AAV-mediated expression of HLA-G for the prevention of experimental ocular graft vs. host disease.
Jacob P Nilles, Darby Roberts, Jacklyn H Salmon, Liujiang Song, Carly O'Dea, Matthew L Hirsch

Mol Ther Methods Clin Dev· June 2023

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Inhibition of experimental autoimmune uveitis by intravitreal AAV-Equine-IL10 gene therapy.
Elizabeth Crabtree, Katy Uribe, Sara M Smith, Darby Roberts, Jacklyn H Salmon, Matthew L Hirsch

PLoS One· August 2022

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Therapeutic Applications of Adeno-Associated Virus (AAV) Gene Transfer of HLA-G in the Eye.
Brian C Gilger, Matthew L Hirsch

Int J Mol Sci· March 2022

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Harnessing the Natural Biology of Adeno-Associated Virus to Enhance the Efficacy of Cancer Gene Therapy.
Jacquelyn J Bower, Liujiang Song, Prabhakar Bastola, Matthew L Hirsch

Viruses· June 2021

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Preparation and Administration of Adeno-associated Virus Vectors for Corneal Gene Delivery.
Liujiang Song, Jacquelyn J Bower, Matthew L Hirsch

Methods Mol Biol· March 2021

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Adeno-Associated Virus Vector Mobilization, Risk Versus Reality.
Liujiang Song, R Jude Samulski, Matthew L Hirsch

Hum Gene Ther· October 2020

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Ocular Tolerability and Immune Response to Corneal Intrastromal AAV- Gene Therapy in New Zealand White Rabbits.
Liujiang Song, Jacquelyn J Bower, Telmo Llanga, Jacklyn H Salmon, Matthew L Hirsch

Mol Ther Methods Clin Dev· September 2020

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Adeno-Associated Virus Mediated Gene Therapy for Corneal Diseases.
Prabhakar Bastola, Liujiang Song, Brian C Gilger, Matthew L Hirsch

Pharmaceutics· August 2020

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Intrastromal Gene Therapy Prevents and Reverses Advanced Corneal Clouding in a Canine Model of Mucopolysaccharidosis I.
Keiko Miyadera, Laura Conatser, Telmo A Llanga, Kendall Carlin, Patricia O'Donnell, Matthew L Hirsch

Mol Ther· June 2020

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Adeno-Associated Virus Serotype-Specific Inverted Terminal Repeat Sequence Role in Vector Transgene Expression.
Lauriel F Earley, Laura M Conatser, Victoria M Lue, Amanda L Dobbins, Chengwen Li, Matthew L Hirsch

Hum Gene Ther· February 2020

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AAV-mediated expression of HLA-G1/5 reduces severity of experimental autoimmune uveitis.
Elizabeth Crabtree, Liujiang Song, Telmo Llanga, Jacquelyn J Bower, Megan Cullen, Matthew L Hirsch

Sci Rep· December 2019

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Gene Delivery to Human Limbal Stem Cells Using Viral Vectors.
Liujiang Song, Zhenwei Song, Nathaniel J Fry, Laura Conatser, Telmo Llanga, Matthew L Hirsch

Hum Gene Ther· November 2019

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Serotype survey of AAV gene delivery via subconjunctival injection in mice.
Liujiang Song, Telmo Llanga, Laura M Conatser, Violeta Zaric, Brian C Gilger, Matthew L Hirsch

Gene Ther· September 2018

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Double-stranded RNA innate immune response activation from long-term adeno-associated virus vector transduction.
Wenwei Shao, Lauriel F Earley, Zheng Chai, Xiaojing Chen, Junjiang Sun, Matthew L Hirsch

JCI Insight· June 2018

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Inhibition of antigen presentation during AAV gene therapy using virus peptides.
Wenwei Shao, Xiaojing Chen, Richard J Samulski, Matthew L Hirsch, Chengwen Li

Hum Mol Genet· February 2018

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AAV vector-meditated expression of HLA-G reduces injury-induced corneal vascularization, immune cell infiltration, and fibrosis.
Matthew L Hirsch, Laura M Conatser, Sara M Smith, Jacklyn H Salmon, Jerry Wu

Sci Rep· December 2017

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Structure-Based Designed Nano-Dysferlin Significantly Improves Dysferlinopathy in BLA/J Mice.
Telmo Llanga, Nadia Nagy, Laura Conatser, Catherine Dial, R Bryan Sutton, Matthew L Hirsch

Mol Ther· September 2017

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Adeno-Associated Virus Vectors and Stem Cells: Friends or Foes?
Nolan Brown, Liujiang Song, Nageswara R Kollu, Matthew L Hirsch

Hum Gene Ther· June 2017

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Integration of a CD19 CAR into the TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells.
Daniel T MacLeod, Jeyaraj Antony, Aaron J Martin, Rachel J Moser, Armin Hekele, Matthew L Hirsch

Mol Ther· April 2017

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Hip region muscular dystrophy and emergence of motor deficits in dysferlin-deficient Bla/J mice.
Nadia Nagy, Randal J Nonneman, Telmo Llanga, Catherine F Dial, Natallia V Riddick, Matthew L Hirsch

Physiol Rep· March 2017

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