Publications by authors named "Matthew McNeil"

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Advancing the antituberculosis activity of nitropicolinic acids and amides.
Andrew M Thompson, Chen-Yi Cheung, Matthew B McNeil, Ashley C Campbell, Monika Záhorszká

Eur J Med Chem· January 2026

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Mutations in the Esx-3 secretion system confer resistance to multiple chemical scaffolds in .
Theresa O'Malley, Matthew B McNeil, Devon Dennison, Thomas Ioerger, Tanya Parish

Microbiology (Reading)· November 2025

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Structure and assembly of the MmpL5/MmpS5 efflux transporter from Mycobacterium tuberculosis.
Zhiqi Xiong, Xiaolin Yang, Shule Wang, Caitlan J Smart, Hazel M Sisson, Matthew B McNeil

Nat Commun· May 2025

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Verapamil and its metabolite norverapamil inhibit the MmpS5L5 efflux pump to increase bedaquiline activity.
Adam J Fountain, Natalie J E Waller, Chen-Yi Cheung, William Jowsey, Michael T Chrisp, Matthew B McNeil

Proc Natl Acad Sci U S A· April 2025

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Whole genome CRISPRi screening identifies druggable vulnerabilities in an isoniazid resistant strain of Mycobacterium tuberculosis.
XinYue Wang, William J Jowsey, Chen-Yi Cheung, Caitlan J Smart, Hannah R Klaus, Matthew B McNeil

Nat Commun· November 2024

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Identification of Chemical Scaffolds That Inhibit the Respiratory Complex Succinate Dehydrogenase.
Cara Adolph, Kiel Hards, Zoe C Williams, Chen-Yi Cheung, Laura M Keighley, Matthew B McNeil

ACS Infect Dis· October 2024

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Dual transcriptional inhibition of glutamate and alanine racemase is synergistic in .
Matthew B McNeil, Gregory M Cook, Kurt L Krause

Microbiology (Reading)· August 2024

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Blueprints for ATP machinery will aid tuberculosis drug design.
Gregory M Cook, Matthew B McNeil

Nature· July 2024

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Antibiotic resistance in alters tolerance to cell wall-targeting inhibitors.
William J Jowsey, Gregory M Cook, Matthew B McNeil

JAC Antimicrob Resist· June 2024

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A dual-targeting succinate dehydrogenase and FF-ATP synthase inhibitor rapidly sterilizes replicating and non-replicating Mycobacterium tuberculosis.
Cara Adolph, Chen-Yi Cheung, Matthew B McNeil, William J Jowsey, Zoe C Williams

Cell Chem Biol· April 2024

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The Untapped Potential of Narrative as a Tool in Aviation Mental Health and Certification.
William R Hoffman, Matthew McNeil, Anthony Tvaryanas

Aerosp Med Hum Perform· March 2024

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Deletion of Rv2571c confers resistance to arylamide compounds in .
Catherine D Shelton, Matthew B McNeil, Julie V Early, Thomas R Ioerger, Tanya Parish

Antimicrob Agents Chemother· May 2023

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The evolution of antibiotic resistance is associated with collateral drug phenotypes in Mycobacterium tuberculosis.
Natalie J E Waller, Chen-Yi Cheung, Gregory M Cook, Matthew B McNeil

Nat Commun· March 2023

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Characterizing in vivo loss of virulence of an HN878 Mycobacterium tuberculosis isolate from a genetic duplication event.
Bryan J Berube, Sasha E Larsen, Matthew B McNeil, Valerie A Reese, Tiffany Pecor

Tuberculosis (Edinb)· December 2022

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Novel chemical entities inhibiting Mycobacterium tuberculosis growth identified by phenotypic high-throughput screening.
Anuradha Kumar, Somsundaram Chettiar, Brian S Brown, Julie Early, Juliane Ollinger, Matthew McNeil

Sci Rep· September 2022

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Uncovering interactions between mycobacterial respiratory complexes to target drug-resistant .
Matthew B McNeil, Chen-Yi Cheung, Natalie J E Waller, Cara Adolph, Cassandra L Chapman

Front Cell Infect Microbiol· September 2022

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Impaired Succinate Oxidation Prevents Growth and Influences Drug Susceptibility in Mycobacterium tuberculosis.
Cara Adolph, Matthew B McNeil, Gregory M Cook

mBio· August 2022

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Correction for Shelton et al., "Deletion of Rv2571c Confers Resistance to Arylamide Compounds in Mycobacterium tuberculosis".
Catherine D Shelton, Matthew B McNeil, Julie V Early, Thomas R Ioerger, Tanya Parish

Antimicrob Agents Chemother· August 2022

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Deciphering functional redundancy and energetics of malate oxidation in mycobacteria.
Liam K Harold, Adrian Jinich, Kiel Hards, Alexandra Cordeiro, Laura M Keighley, Matthew B McNeil

J Biol Chem· May 2022

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Triazolopyrimidines Target Aerobic Respiration in Mycobacterium tuberculosis.
Catherine Shelton, Matthew McNeil, Renee Allen, Lindsay Flint, Dara Russell

Antimicrob Agents Chemother· April 2022

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Utilization of CRISPR interference to investigate the contribution of genes to pathogenesis in a macrophage model of Mycobacterium tuberculosis infection.
Chen-Yi Cheung, Matthew B McNeil, Gregory M Cook

J Antimicrob Chemother· February 2022

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An amiloride derivative is active against the FF-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis.
Kiel Hards, Chen-Yi Cheung, Natalie Waller, Cara Adolph, Laura Keighley, Matthew B McNeil

Commun Biol· February 2022

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Multiplexed transcriptional repression identifies a network of bactericidal interactions between mycobacterial respiratory complexes.
Matthew B McNeil, Heath W Ryburn, Justin Tirados, Chen-Yi Cheung, Gregory M Cook

iScience· January 2022

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CRISPR interference identifies vulnerable cellular pathways with bactericidal phenotypes in Mycobacterium tuberculosis.
Matthew B McNeil, Laura M Keighley, Josephine R Cook, Chen-Yi Cheung, Gregory M Cook

Mol Microbiol· October 2021

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Novel Trifluoromethyl Pyrimidinone Compounds With Activity Against .
Erik Hembre, Julie V Early, Joshua Odingo, Catherine Shelton, Olena Anoshchenko, Matthew B McNeil

Front Chem· April 2021

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