Publications by authors named "Matthew Mitsche"

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Low MBOAT7 expression, a genetic risk for MASH, promotes a profibrotic pathway involving hepatocyte TAZ upregulation.
Mary P Moore, Xiaobo Wang, John Paul Kennelly, Hongxue Shi, Yuki Ishino, Matthew A Mitsche

Hepatology· February 2025

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Measurement of lipogenic flux by deuterium resolved mass spectrometry.
Xiaorong Fu, Stanisław Deja, Justin A Fletcher, Norma N Anderson, Monika Mizerska, Matthew A Mitsche

Nat Commun· June 2021

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Hepatic deletion of Mboat7 (LPIAT1) causes activation of SREBP-1c and fatty liver.
Mingfeng Xia, Preethi Chandrasekaran, Shunxing Rong, Xiaorong Fu, Matthew A Mitsche

J Lipid Res· February 2021

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Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress.
Suneeta Chimalapati, Marcela de Souza Santos, Alexander E Lafrance, Ann Ray, Wan-Ru Lee, Matthew A Mitsche

Elife· August 2020

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A Medicinal Chemistry-Driven Approach Identified the Sterol Isomerase EBP as the Molecular Target of TASIN Colorectal Cancer Toxins.
Panayotis C Theodoropoulos, Wentian Wang, Albert Budhipramono, Bonne M Thompson, Nikhil Madhusudhan, Matthew A Mitsche

J Am Chem Soc· April 2020

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Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression.
Alisson C Cardoso, Nicholas T Lam, Jainy J Savla, Yuji Nakada, Ana Helena M Pereira, Matthew A Mitsche

Nat Metab· February 2020

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Insights into lipid accumulation in skeletal muscle in dysferlin-deficient mice.
Anil K Agarwal, Katie Tunison, Matthew A Mitsche, Jeffrey G McDonald, Abhimanyu Garg

J Lipid Res· December 2019

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Three-phase liquid extraction: a simple and fast method for lipidomic workflows.
Gonçalo Vale, Sarah A Martin, Matthew A Mitsche, Bonne M Thompson, Kaitlyn M Eckert

J Lipid Res· March 2019

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Patatin-like phospholipase domain–containing protein 3 promotes transfer of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets.
Matthew A Mitsche, Helen H Hobbs, Jonathan C Cohen

J Biol Chem· May 2018

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Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI.
Yue Zhang, Durga Udayakumar, Ling Cai, Zeping Hu, Payal Kapur, Matthew A Mitsche

JCI Insight· August 2017

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Transcription Factor Hepatocyte Nuclear Factor-1β Regulates Renal Cholesterol Metabolism.
Karam Aboudehen, Min Soo Kim, Matthew Mitsche, Kristina Garland, Norma Anderson

J Am Soc Nephrol· August 2016

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Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
Mahesh S Padanad, Georgia Konstantinidou, Niranjan Venkateswaran, Margherita Melegari, Smita Rindhe, Matthew Mitsche

Cell Rep· August 2016

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Contribution of Accelerated Degradation to Feedback Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Metabolism in the Liver.
Seonghwan Hwang, Isamu Z Hartman, Leona N Calhoun, Kristina Garland, Gennipher A Young, Matthew A Mitsche

J Biol Chem· June 2016

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6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Ruiting Lin, Shannon Elf, Changliang Shan, Hee-Bum Kang, Quanjiang Ji, Matthew Mitsche

Nat Cell Biol· November 2015

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Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.
Lu Gao, Elizabeth H Rabbitt, Jennifer C Condon, Nora E Renthal, John M Johnston, Matthew A Mitsche

J Clin Invest· July 2015

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Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways.
Matthew A Mitsche, Jeffrey G McDonald, Helen H Hobbs, Jonathan C Cohen

Elife· June 2015

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Relative roles of ABCG5/ABCG8 in liver and intestine.
Jin Wang, Matthew A Mitsche, Dieter Lütjohann, Jonathan C Cohen, Xiao-Song Xie

J Lipid Res· February 2015

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Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance.
Young-Ah Moon, Courtney R Ochoa, Matthew A Mitsche, Robert E Hammer, Jay D Horton

J Lipid Res· December 2014

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Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport.
Chendong Yang, Bookyung Ko, Christopher T Hensley, Lei Jiang, Ajla T Wasti, Matthew Mitsche

Mol Cell· November 2014

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Surface tensiometry of apolipoprotein B domains at lipid interfaces suggests a new model for the initial steps in triglyceride-rich lipoprotein assembly.
Matthew A Mitsche, Laura E Packer, Jeffrey W Brown, Z Gordon Jiang, Donald M Small

J Biol Chem· March 2014

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Surface pressure-dependent conformation change of apolipoprotein-derived amphipathic α-helices.
Matthew A Mitsche, Donald M Small

J Lipid Res· June 2013

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C-terminus of apolipoprotein A-I removes phospholipids from a triolein/phospholipids/water interface, but the N-terminus does not: a possible mechanism for nascent HDL assembly.
Matthew A Mitsche, Donald M Small

Biophys J· July 2011

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Adsorption of egg phosphatidylcholine to an air/water and triolein/water bubble interface: use of the 2-dimensional phase rule to estimate the surface composition of a phospholipid/triolein/water surface as a function of surface pressure.
Matthew A Mitsche, Libo Wang, Donald M Small

J Phys Chem B· March 2010

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The adsorption of biological peptides and proteins at the oil/water interface. A potentially important but largely unexplored field.
Donald M Small, Libo Wang, Matthew A Mitsche

J Lipid Res· April 2009

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Interfacial properties of a complex multi-domain 490 amino acid peptide derived from apolipoprotein B (residues 292-782).
Matthew A Mitsche, Libo Wang, Z Gordon Jiang, C James McKnight, Donald M Small

Langmuir· February 2009

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