Publications by authors named "Matthew Oser"

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Loss of NOTCH2 creates a TRIM28-dependent vulnerability in small cell lung cancer.
Deli Hong, Ying Lyu, Richa Nayak, Justin S Becker, Matthew A Booker, Matthew G Oser

Dev Cell· December 2025

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Targeting G1-S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors.
Shilpa Singh, Catherine E Gleason, Min Fang, Yasmin N Laimon, Vishal Khivansara, Matthew G Oser

Nature· October 2025

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EED Maintains the Small Cell Lung Cancer Neuroendocrine Phenotype and Drives Lung Cancer Histological Transformation.
Yixiang Li, Yasmin N Laimon, Hyeonseo Cho, Marina Vivero, Gabriel Roberti De Oliveira, Matthew G Oser

bioRxiv· July 2025

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Efficacy and Safety of Tarlatamab in a Patient With Advanced Delta-Like Ligand 3-Positive Large Cell Neuroendocrine Lung Carcinoma and Untreated Brain Metastases: A Case Report.
Eleonora Gariazzo, Sanna Laaksonen, Stephanie Canty, Guilherme Rossato De Almeida, Igor Odintsov, Matthew G Oser

JCO Precis Oncol· June 2025

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A circular RNA in neuroendocrine carcinomas.
Yixiang Li, Matthew G Oser

Cancer Cell· May 2025

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The Lung Cancer Autochthonous Model Gene Expression Database Enables Cross-Study Comparisons of the Transcriptomic Landscapes Across Mouse Models.
Ling Cai, Fangjiang Wu, Qinbo Zhou, Ying Gao, Bo Yao, Matthew G Oser

Cancer Res· May 2025

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Detecting Small Cell Transformation in Patients with Advanced EGFR Mutant Lung Adenocarcinoma through Epigenomic cfDNA Profiling.
Talal El Zarif, Catherine B Meador, Xintao Qiu, Ji-Heui Seo, Matthew P Davidsohn, Matthew G Oser

Clin Cancer Res· September 2024

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Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer.
Leslie Duplaquet, Kevin So, Alexander W Ying, Shreoshi Pal Choudhuri, Xinyue Li, Matthew G Oser

Cancer Cell· August 2024

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Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity.
Shilpa Singh, Catherine E Gleason, Min Fang, Yasmin N Laimon, Vishal Khivansara, Matthew G Oser

bioRxiv· August 2024

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Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation.
Pratik N P Singh, Wei Gu, Shariq Madha, Allen W Lynch, Paloma Cejas, Matthew G Oser

Cell Stem Cell· July 2024

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A Lung Cancer Mouse Model Database.
Ling Cai, Ying Gao, Ralph J DeBerardinis, George Acquaah-Mensah, Vassilis Aidinis, Matthew G Oser

bioRxiv· May 2024

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Author Correction: Liquid biopsy epigenomic profiling for cancer subtyping.
Sylvan C Baca, Ji-Heui Seo, Matthew P Davidsohn, Brad Fortunato, Karl Semaan, Matthew G Oser

Nat Med· March 2024

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Genetically-engineered mouse models of small cell lung cancer: the next generation.
Matthew G Oser, David MacPherson, Trudy G Oliver, Julien Sage, Kwon-Sik Park

Oncogene· February 2024

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Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation.
Pratik N P Singh, Wei Gu, Shariq Madha, Allen W Lynch, Paloma Cejas, Matthew G Oser

bioRxiv· January 2024

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Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer.
Leslie Duplaquet, Kevin So, Alexander W Ying, Xinyue Li, Yixiang Li, Matthew G Oser

bioRxiv· January 2024

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Liquid biopsy epigenomic profiling for cancer subtyping.
Sylvan C Baca, Ji-Heui Seo, Matthew P Davidsohn, Brad Fortunato, Karl Semaan, Matthew G Oser

Nat Med· November 2023

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Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1.
Yixiang Li, Navin R Mahadevan, Leslie Duplaquet, Deli Hong, Yavuz T Durmaz, Matthew G Oser

Cell Rep Med· November 2023

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KDM6A epigenetically regulates subtype plasticity in small cell lung cancer.
Leslie Duplaquet, Yixiang Li, Matthew A Booker, Yingtian Xie, Sarah Naomi Olsen, Matthew G Oser

Nat Cell Biol· September 2023

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Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1.
Hsiao-Yun Chen, Yavuz T Durmaz, Yixiang Li, Amin H Sabet, Amir Vajdi, Matthew G Oser

Nat Commun· August 2022

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Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer.
Deli Hong, Erik H Knelson, Yixiang Li, Yavuz T Durmaz, Wenhua Gao, Matthew G Oser

Cancer Res· January 2022

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Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.
Navin R Mahadevan, Erik H Knelson, Jacquelyn O Wolff, Amir Vajdi, Maria Saigí, Matthew G Oser

Cancer Discov· August 2021

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Targeting oncoproteins with a positive selection assay for protein degraders.
Vidyasagar Koduri, Leslie Duplaquet, Benjamin L Lampson, Adam C Wang, Amin H Sabet, Matthew G Oser

Sci Adv· February 2021

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New Approaches to SCLC Therapy: From the Laboratory to the Clinic.
John T Poirier, Julie George, Taofeek K Owonikoko, Anton Berns, Elisabeth Brambilla, Matthew Oser

J Thorac Oncol· April 2020

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CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.
Hua Zhang, Camilla L Christensen, Ruben Dries, Matthew G Oser, Jiehui Deng

Cancer Cell· January 2020

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The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.
Matthew G Oser, Amin H Sabet, Wenhua Gao, Abhishek A Chakraborty, Anna C Schinzel

Genes Dev· December 2019

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