Publications by authors named "Matthew Pearn"

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Correction: An Anti-β-Amyloid vaccine for treating cognitive deficits in a mouse model of down syndrome.
Pavel V Belichenko, Rime Madani, Lorianne Rey-Bellet, Maria Pihlgren, Ann Becker, Matthew L Pearn

PLoS One· May 2025

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Severe Acute Respiratory Syndrome Coronavirus-2 Infections in Critical Care Staff: Beware the Risks Beyond the Bedside.
Kate El Bouzidi, Tasneem Pirani, Carolina Rosadas, Samreen Ijaz, Matthew Pearn

Crit Care Med· March 2021

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Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model.
Xu-Qiao Chen, Ahmad Salehi, Matthew L Pearn, Cassia Overk, Phuong D Nguyen

Alzheimers Dement· February 2021

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Standards for preclinical research and publications in developmental anaesthetic neurotoxicity: expert opinion statement from the SmartTots preclinical working group.
Gregory A Chinn, Matthew L Pearn, Laszlo Vutskits, Cyrus D Mintz, Andreas W Loepke

Br J Anaesth· May 2020

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Swedish Nerve Growth Factor Mutation (NGF) Defines a Role for TrkA and p75 in Nociception.
Kijung Sung, Luiz F Ferrari, Wanlin Yang, ChiHye Chung, Xiaobei Zhao, Matthew L Pearn

J Neurosci· April 2018

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Pathophysiology Associated with Traumatic Brain Injury: Current Treatments and Potential Novel Therapeutics.
Matthew L Pearn, Ingrid R Niesman, Junji Egawa, Atsushi Sawada, Angels Almenar-Queralt

Cell Mol Neurobiol· May 2017

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The Effect of Clevidipine on Cerebral Blood Flow Velocity and Carbon Dioxide Reactivity in Human Volunteers.
Brian P Lemkuil, Brian T Gierl, Piyush M Patel, Matthew L Pearn, Liem C Nguyen

J Neurosurg Anesthesiol· October 2016

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Membrane lipid rafts and neurobiology: age-related changes in membrane lipids and loss of neuronal function.
Junji Egawa, Matthew L Pearn, Brian P Lemkuil, Piyush M Patel, Brian P Head

J Physiol· August 2016

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An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.
Pavel V Belichenko, Rime Madani, Lorianne Rey-Bellet, Maria Pihlgren, Ann Becker, Matthew L Pearn

PLoS One· August 2016

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Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration.
Wei Xu, April M Weissmiller, Joseph A White, Fang Fang, Xinyi Wang, Matthew L Pearn

J Clin Invest· May 2016

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A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP.
April M Weissmiller, Orlangie Natera-Naranjo, Sol M Reyna, Matthew L Pearn, Xiaobei Zhao

PLoS One· November 2015

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Pre-operative cellularity mapping and intra-MRI surgery: potential for improving neurosurgical biopsies.
Clark C Chen, Nathan S White, Nikdokht Farid, Peter Kobalka, Lawrence Hansen, Matthew Pearn

Expert Rev Med Devices· January 2015

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Real-time imaging of axonal transport of quantum dot-labeled BDNF in primary neurons.
Xiaobei Zhao, Yue Zhou, April M Weissmiller, Matthew L Pearn, William C Mobley

J Vis Exp· September 2014

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Aging and intellectual disability: insights from mouse models of Down syndrome.
Aarti Ruparelia, Matthew L Pearn, William C Mobley

Dev Disabil Res Rev· March 2014

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Cognitive and pharmacological insights from the Ts65Dn mouse model of Down syndrome.
Aarti Ruparelia, Matthew L Pearn, William C Mobley

Curr Opin Neurobiol· October 2012

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Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation.
Matthew L Pearn, Yue Hu, Ingrid R Niesman, Hemal H Patel, John C Drummond

Anesthesiology· February 2012

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Isoflurane neurotoxicity is mediated by p75NTR-RhoA activation and actin depolymerization.
Brian P Lemkuil, Brian P Head, Matthew L Pearn, Hemal H Patel, John C Drummond

Anesthesiology· January 2011

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Loss of caveolin-1 accelerates neurodegeneration and aging.
Brian P Head, Jason N Peart, Mathivadhani Panneerselvam, Takaakira Yokoyama, Matthew L Pearn

PLoS One· December 2010

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