Publications by authors named "Matthew Tudor"

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Discovery of a Novel Series of -Indolinone-Based Glutarimides as Highly Efficacious and Selective IKZF2 Molecular Glue Degraders.
Xuqing Zhang, Harshil Dhruv, Qiaolin Deng, Matthew Tudor, Nelisa Bechtel

J Med Chem· September 2025

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Overcoming CK1α liability in the discovery of a series of isoIndolinone Glutarimides as selective IKZF2 molecular glue degraders.
Xuqing Zhang, Qiaolin Deng, Harshil Dhruv, Matthew Tudor, Rakesh Nagilla

Bioorg Med Chem Lett· August 2025

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A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
Keith P Moore, Adam G Schwaid, Matthew Tudor, Sangho Park, Douglas C Beshore

ACS Chem Biol· September 2022

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Prediction Accuracy of Production ADMET Models as a Function of Version: Activity Cliffs Rule.
Robert P Sheridan, J Chris Culberson, Elizabeth Joshi, Matthew Tudor, Prabha Karnachi

J Chem Inf Model· July 2022

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Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Na1.7 for the Treatment of Pain.
Gregory L Adams, Parul S Pall, Steven M Grauer, Xiaoping Zhou, Jeanine E Ballard, Matthew Tudor

J Med Chem· January 2022

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Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen.
Marina Bukhtiyarova, Erica M Cook, Paula J Hancock, Alan W Hruza, Anthony W Shaw, Matthew Tudor

ACS Med Chem Lett· January 2021

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Deep learning approaches in predicting ADMET properties.
Elena L Cáceres, Matthew Tudor, Alan C Cheng

Future Med Chem· November 2020

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Nearest Neighbor Gaussian Process for Quantitative Structure-Activity Relationships.
Anthony DiFranzo, Robert P Sheridan, Andy Liaw, Matthew Tudor

J Chem Inf Model· October 2020

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Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery.
Xin Cindy Yan, John M Sanders, Ying-Duo Gao, Matthew Tudor, Andrew M Haidle

J Chem Inf Model· September 2020

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Experimental Error, Kurtosis, Activity Cliffs, and Methodology: What Limits the Predictivity of Quantitative Structure-Activity Relationship Models?
Robert P Sheridan, Prabha Karnachi, Matthew Tudor, Yuting Xu, Andy Liaw

J Chem Inf Model· April 2020

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Diversity & tractability revisited in collaborative small molecule phenotypic screening library design.
Brian R Lahue, Meir Glick, Matthew Tudor, Scott Arne Johnson, Janet Diratsouian

Bioorg Med Chem· January 2020

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Endogenous Locus Reporter Assays.
Yaping Liu, Jeffrey Hermes, Jing Li, Matthew Tudor

Methods Mol Biol· January 2019

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High-Content Reporter Assays.
Erica Cook, Jeffrey Hermes, Jing Li, Matthew Tudor

Methods Mol Biol· January 2019

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Inflammation-Induced, STING-Dependent Autophagy Restricts Zika Virus Infection in the Drosophila Brain.
Yuan Liu, Beth Gordesky-Gold, Michael Leney-Greene, Nathan L Weinbren, Matthew Tudor

Cell Host Microbe· July 2018

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Is Multitask Deep Learning Practical for Pharma?
Bharath Ramsundar, Bowen Liu, Zhenqin Wu, Andreas Verras, Matthew Tudor

J Chem Inf Model· August 2017

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Deorphanization strategies for dark chemical matter.
Anne Mai Wassermann, Matthew Tudor, Meir Glick

Drug Discov Today Technol· March 2017

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Representing high throughput expression profiles via perturbation barcodes reveals compound targets.
Tracey M Filzen, Peter S Kutchukian, Jeffrey D Hermes, Jing Li, Matthew Tudor

PLoS Comput Biol· February 2017

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Translatability: what does it mean in drug discovery?
Matthew Tudor, Jeffery Hermes, Jing Li

Drug Discov Today· June 2016

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Nup98 promotes antiviral gene expression to restrict RNA viral infection in Drosophila.
Debasis Panda, Pau Pascual-Garcia, Margaret Dunagin, Matthew Tudor, Kaycie C Hopkins

Proc Natl Acad Sci U S A· September 2014

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Dicer-2 processes diverse viral RNA species.
Leah R Sabin, Qi Zheng, Pramod Thekkat, Jamie Yang, Gregory J Hannon, Matthew Tudor

PLoS One· August 2013

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Parsimonious discovery of synergistic drug combinations.
Bryan Severyn, Robert A Liehr, Alex Wolicki, Kevin H Nguyen, Edward M Hudak, Matthew Tudor

ACS Chem Biol· December 2011

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Comparative RNAi screening reveals host factors involved in enterovirus infection of polarized endothelial monolayers.
Carolyn B Coyne, Rebecca Bozym, Stefanie A Morosky, Sheri L Hanna, Amitava Mukherjee, Matthew Tudor

Cell Host Microbe· January 2011

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Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain.
Matthew Tudor, Schahram Akbarian, Richard Z Chen, Rudolf Jaenisch

Proc Natl Acad Sci U S A· November 2002

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