Publications by authors named "Matthew Whiteman"

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Neuroprotection by post-stroke administration of the slow-releasing hydrogen sulfide (HS) donor AP39: Long-Term functional, MRI, and molecular evidence in a rodent stroke model.
Pomierny Bartosz, Krzyżanowska Weronika, Skórkowska Alicja, Jurczyk Jakub, Przejczowska-Pomierny Katarzyna, Whiteman Matthew

Eur J Pharmacol· December 2025

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The mitochondria-targeted hydrogen sulfide donor AP39 reduces cortical stroke volume and improves motor function in a photothrombotic stroke model in mice in a sex-dependent manner.
Jakub Jurczyk, Zuzanna Guzda, Alicja Skórkowska, Żaneta Broniowska, Małgorzata Piechaczek, Matthew Whiteman

Neuropharmacology· November 2025

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AP39, a novel mitochondria-targeted hydrogen sulfide donor, promotes cutaneous wound healing in an in vivo murine model of acute frostbite injury.
George J Dugbartey, Lucas N Penney, Lauren Mills, Max Y Zhang, Smriti Juriasingani, Matthew Whiteman

Biomed Pharmacother· February 2025

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Mitochondria-targeted hydrogen sulfide donor reduces fatty liver and obesity in mice fed a high fat diet by inhibiting de novo lipogenesis and inflammation via mTOR/SREBP-1 and NF-κB signaling pathways.
Aneta Stachowicz, Klaudia Czepiel, Anna Wiśniewska, Kamila Stachyra, Magdalena Ulatowska-Białas, Matthew Whiteman

Pharmacol Res· November 2024

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Mitochondria-targeted hydrogen sulfide donor reduces atherogenesis by changing macrophage phenotypes and increasing UCP1 expression in vascular smooth muscle cells.
Aneta Stachowicz, Anna Wiśniewska, Klaudia Czepiel, Bartosz Pomierny, Alicja Skórkowska, Matthew Whiteman

Biomed Pharmacother· November 2024

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Neuroprotective Actions of Hydrogen Sulfide-Releasing Compounds in Isolated Bovine Retinae.
Leah Bush, Jenaye Robinson, Anthonia Okolie, Fatima Muili, Catherine A Opere, Matthew Whiteman

Pharmaceuticals (Basel)· October 2024

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Hydrogen sulfide supplementation as a potential treatment for primary mitochondrial diseases.
Luke Slade, Colleen S Deane, Nathaniel J Szewczyk, Timothy Etheridge, Matthew Whiteman

Pharmacol Res· May 2024

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Azithromycin Prescriptions in Children From 2016-2018: Room for Improvement.
Skylar Petrone, Matthew Whiteman, Shipra Gupta

Clin Pediatr (Phila)· February 2024

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The Hydrogen Sulfide Donor AP39 Reduces Glutamate-mediated Excitotoxicity in a Rat Model of Brain Ischemia.
Alicja Skórkowska, Weronika Krzyżanowska, Beata Bystrowska, Roberta Torregrossa, Matthew Whiteman

Neuroscience· February 2024

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The mitochondria-targeted sulfide delivery molecule attenuates drugs-induced gastropathy. Involvement of heme oxygenase pathway.
Katarzyna Magierowska, Dagmara Wójcik-Grzybek, Edyta Korbut, Dominik Bakalarz, Grzegorz Ginter, Matthew Whiteman

Redox Biol· October 2023

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Static Cold Storage with Mitochondria-Targeted Hydrogen Sulfide Donor Improves Renal Graft Function in an Ex Vivo Porcine Model of Controlled Donation-after-Cardiac-Death Kidney Transplantation.
George J Dugbartey, Smriti Juriasingani, Mahms Richard-Mohamed, Andrew Rasmussen, Max Levine, Matthew Whiteman

Int J Mol Sci· September 2023

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Mitochondrial sulfide promotes life span and health span through distinct mechanisms in developing versus adult treated .
Adriana Raluca Vintila, Luke Slade, Michael Cooke, Craig R G Willis, Roberta Torregrossa, Matthew Whiteman

Proc Natl Acad Sci U S A· August 2023

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Hydrogen sulfide donor AP123 restores endothelial nitric oxide-dependent vascular function in hyperglycemia via a CREB-dependent pathway.
Rosangela Montanaro, Valentina Vellecco, Roberta Torregrossa, Gian Marco Casillo, Onorina Laura Manzo, Matthew Whiteman

Redox Biol· June 2023

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Hydrogen sulfide as an anti-calcification stratagem in human aortic valve: Altered biogenesis and mitochondrial metabolism of HS lead to HS deficiency in calcific aortic valve disease.
Zsolt Combi, László Potor, Péter Nagy, Katalin Éva Sikura, Tamás Ditrói, Matthew Whiteman

Redox Biol· April 2023

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Mitochondrial H2S donor AP39 induces stomatal closure by modulating guard cell mitochondrial activity.
Rosario Pantaleno, Denise Scuffi, Alex Costa, Elina Welchen, Roberta Torregrossa, Matthew Whiteman

Plant Physiol· March 2023

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Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy.
Rebecca A Ellwood, Luke Slade, Jonathan Lewis, Roberta Torregrossa, Surabhi Sudevan, Matthew Whiteman

Commun Biol· November 2022

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Mitochondria-targeted hydrogen sulfide donors versus acute oxidative gastric mucosal injury.
Katarzyna Magierowska, Edyta Korbut, Dagmara Wójcik-Grzybek, Dominik Bakalarz, Zbigniew Sliwowski, Matthew Whiteman

J Control Release· August 2022

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Mitochondria-Targeted Hydrogen Sulfide Delivery Molecules Protect Against UVA-Induced Photoaging in Human Dermal Fibroblasts, and in Mouse Skin .
Jinapath Lohakul, Saowanee Jeayeng, Anyamanee Chaiprasongsuk, Roberta Torregrossa, Mark E Wood, Matthew Whiteman

Antioxid Redox Signal· June 2022

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Vasorelaxant Activity of AP39, a Mitochondria-Targeted HS Donor, on Mouse Mesenteric Artery Rings In Vitro.
Leonardo A da Costa Marques, Simone A Teixeira, Flávia N de Jesus, Mark E Wood, Roberta Torregrossa, Matthew Whiteman

Biomolecules· February 2022

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Effect of hydrogen sulfide on glycolysis-based energy production in mouse erythrocytes.
Eden T Wondimu, Quanxi Zhang, Zhuping Jin, Ming Fu, Roberta Torregrossa, Matthew Whiteman

J Cell Physiol· January 2022

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Hydrogen Sulfide Is a Novel Protector of the Retinal Glycocalyx and Endothelial Permeability Barrier.
Claire L Allen, Katarzyna Wolanska, Naseeb K Malhi, Andrew V Benest, Mark E Wood, Matthew Whiteman

Front Cell Dev Biol· September 2021

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The Hypothermic Effect of Hydrogen Sulfide Is Mediated by the Transient Receptor Potential Ankyrin-1 Channel in Mice.
Emoke Olah, Zoltan Rumbus, Viktoria Kormos, Valeria Tekus, Eszter Pakai, Matthew Whiteman

Pharmaceuticals (Basel)· September 2021

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Evaluating the Effects of Subnormothermic Perfusion with AP39 in a Novel Blood-Free Model of Ex Vivo Kidney Preservation and Reperfusion.
Smriti Juriasingani, Ashley Jackson, Max Yulin Zhang, Aushanth Ruthirakanthan, George J Dugbartey, Matthew Whiteman

Int J Mol Sci· July 2021

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The Slow-Releasing and Mitochondria-Targeted Hydrogen Sulfide (HS) Delivery Molecule AP39 Induces Brain Tolerance to Ischemia.
Bartosz Pomierny, Weronika Krzyżanowska, Jakub Jurczyk, Alicja Skórkowska, Beata Strach, Matthew Whiteman

Int J Mol Sci· July 2021

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GYY4137 and Sodium Hydrogen Sulfide Relaxations Are Inhibited by L-Cysteine and K7 Channel Blockers in Rat Small Mesenteric Arteries.
Silvijus Abramavicius, Asbjørn G Petersen, Nirthika S Renaltan, Judit Prat-Duran, Roberta Torregrossa, Matthew Whiteman

Front Pharmacol· March 2021

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