Publications by authors named "Matthew Worssam"

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A cell and transcriptome atlas of human arterial vasculature.
Quanyi Zhao, Albert Pedroza, Disha Sharma, Wenduo Gu, Alex Dalal, Matthew Worssam

Cell Genom· December 2025

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Epigenomic landscape of single vascular cells reflects developmental origin and disease risk loci.
Chad S Weldy, Soumya Kundu, João Monteiro, Wenduo Gu, Albert J Pedroza, Matthew D Worssam

Mol Syst Biol· November 2025

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Smooth muscle expression of RNA editing enzyme ADAR1 controls activation of the RNA sensor MDA5 in atherosclerosis.
Chad S Weldy, Qin Li, João P Monteiro, Tim S Peters, Hongchao Guo, Matthew D Worssam

Nat Cardiovasc Res· October 2025

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Preclinical evaluation of high-resolution CT, F-FDG, and F-NaF PET imaging for longitudinal monitoring of atherosclerosis.
Mikayla Tamboline, Jeffrey Collins, William Jackson, Wenduo Gu, Matthew Worssam

Eur J Nucl Med Mol Imaging· September 2025

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A cell and transcriptome atlas of human arterial vasculature.
Quanyi Zhao, Albert Pedroza, Disha Sharma, Wenduo Gu, Alex Dalal, Matthew Worssam

bioRxiv· August 2025

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Premature cell senescence promotes vascular smooth muscle cell phenotypic modulation and resistance to re-differentiation.
Anuradha Kaistha, Sebnem Oc, Abel Martin Garrido, James C K Taylor, Maria Imaz, Matthew D Worssam

Cardiovasc Res· August 2025

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Delineation of a thrombin receptor-stimulated vascular smooth muscle cell transition generating cells in the plaque-stabilizing fibrous cap.
James C K Taylor, Matthew D Worssam, Sebnem Oc, Jordi Lambert, Krishnaa T Mahbubani

Cardiovasc Res· August 2025

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Smooth muscle expression of RNA editing enzyme controls activation of RNA sensor MDA5 in atherosclerosis.
Chad S Weldy, Qin Li, João P Monteiro, Tim S Peters, Hongchao Guo, Matthew D Worssam

bioRxiv· June 2025

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Vascular smooth muscle cell atherosclerosis trajectories characterized at single cell resolution identify causal transcriptomic and epigenomic mechanisms of disease risk.
Daniel Yuhang Li, Soumya Kundu, Paul Cheng, Wenduo Gu, Will Jackson, Matthew Worssam

bioRxiv· June 2025

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The epigenomic landscape of single vascular cells reflects developmental origin and identifies disease risk loci.
Chad S Weldy, Soumya Kundu, João Monteiro, Wenduo Gu, Albert J Pedroza, Matthew D Worssam

bioRxiv· May 2025

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Aryl-hydrocarbon receptor in smooth muscle cells protect against dioxin induced adverse remodeling of atherosclerosis.
Guyu Tracy Qin, Quanyi Zhao, Ayaka Fujita, Isabella Damiani, Meena Easwaran, Matthew Worssam

bioRxiv· November 2024

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Network-based prioritization and validation of regulators of vascular smooth muscle cell proliferation in disease.
Jordi Lambert, Sebnem Oc, Matthew D Worssam, Daniel Häußler, Charles U Solomon

Nat Cardiovasc Res· June 2024

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Comprehensive Integration of Multiple Single-Cell Transcriptomic Data Sets Defines Distinct Cell Populations and Their Phenotypic Changes in Murine Atherosclerosis.
Disha Sharma, Matthew D Worssam, Albert J Pedroza, Alex R Dalal, Haizea Alemany

Arterioscler Thromb Vasc Biol· February 2024

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Genome-Wide Genetic Associations Prioritize Evaluation of Causal Mechanisms of Atherosclerotic Disease Risk.
Thomas Quertermous, Daniel Yuhang Li, Chad S Weldy, Markus Ramste, Disha Sharma, Matthew D Worssam

Arterioscler Thromb Vasc Biol· February 2024

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Mechanisms of vascular smooth muscle cell investment and phenotypic diversification in vascular diseases.
Matthew D Worssam, Helle F Jørgensen

Biochem Soc Trans· November 2021

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Epigenetic Regulation of Vascular Smooth Muscle Cells by Histone H3 Lysine 9 Dimethylation Attenuates Target Gene-Induction by Inflammatory Signaling.
Jennifer L Harman, Lina Dobnikar, Joel Chappell, Benjamin G Stokell, Amanda Dalby, Matthew D Worssam

Arterioscler Thromb Vasc Biol· November 2019

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