Publications by authors named "Matthias Degenhardt"

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The More the Better?─Vitamin E TPGS as a Release Enhancer for Ritonavir/PVPVA Amorphous Solid Dispersions.
Ineke Fahrig, Stefanie Walter, Samuel Kyeremateng, Matthias Degenhardt, Gabriele Sadowski

Mol Pharm· September 2025

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Predicting the Release Mechanism of Amorphous Solid Dispersions: A Combination of Thermodynamic Modeling and In Silico Molecular Simulation.
Stefanie Walter, Paulo G M Mileo, Mohammad Atif Faiz Afzal, Samuel O Kyeremateng, Matthias Degenhardt

Pharmaceutics· October 2024

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Kinetics of Water-Induced Amorphous Phase Separation in Amorphous Solid Dispersions via Raman Mapping.
Adrian Krummnow, Andreas Danzer, Kristin Voges, Samuel O Kyeremateng, Matthias Degenhardt

Pharmaceutics· May 2023

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Thermodynamic Modeling of the Amorphous Solid Dispersion-Water Interfacial Layer and Its Impact on the Release Mechanism.
Stefanie Dohrn, Samuel O Kyeremateng, Esther Bochmann, Ekaterina Sobich, Andrea Wahl, Matthias Degenhardt

Pharmaceutics· May 2023

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The Role of Titanium Dioxide (E171) and the Requirements for Replacement Materials in Oral Solid Dosage Forms: An IQ Consortium Working Group Review.
Ross Blundell, Paul Butterworth, Anne Charlier, Dominick Daurio, Matthias Degenhardt

J Pharm Sci· November 2022

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Explaining the Release Mechanism of Ritonavir/PVPVA Amorphous Solid Dispersions.
Adrian Krummnow, Andreas Danzer, Kristin Voges, Stefanie Dohrn, Samuel O Kyeremateng, Matthias Degenhardt

Pharmaceutics· September 2022

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A Hot-Melt Extrusion Risk Assessment Classification System for Amorphous Solid Dispersion Formulation Development.
Samuel O Kyeremateng, Kristin Voges, Stefanie Dohrn, Ekaterina Sobich, Ute Lander, Matthias Degenhardt

Pharmaceutics· May 2022

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Predicting process design spaces for spray drying amorphous solid dispersions.
Stefanie Dohrn, Pranay Rawal, Christian Luebbert, Kristin Lehmkemper, Samuel O Kyeremateng, Matthias Degenhardt

Int J Pharm X· December 2021

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Molecular-Level Examination of Amorphous Solid Dispersion Dissolution.
Mohammad Atif Faiz Afzal, Kristin Lehmkemper, Ekaterina Sobich, Thomas F Hughes, David J Giesen, Matthias Degenhardt

Mol Pharm· November 2021

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Solvent influence on the phase behavior and glass transition of Amorphous Solid Dispersions.
Stefanie Dohrn, Christian Luebbert, Kristin Lehmkemper, Samuel O Kyeremateng, Matthias Degenhardt

Eur J Pharm Biopharm· January 2021

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Thermodynamic Modeling of Solvent-Impact on Phase Separation in Amorphous Solid Dispersions during Drying.
Stefanie Dohrn, Philipp Reimer, Christian Luebbert, Kristin Lehmkemper, Samuel O Kyeremateng, Matthias Degenhardt

Mol Pharm· July 2020

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Phase behavior of pharmaceutically relevant polymer/solvent mixtures.
Stefanie Dohrn, Christian Luebbert, Kristin Lehmkemper, Samuel O Kyeremateng, Matthias Degenhardt

Int J Pharm· March 2020

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Development and Performance of a Highly Sensitive Model Formulation Based on Torasemide to Enhance Hot-Melt Extrusion Process Understanding and Process Development.
Rachel C Evans, Samuel O Kyeremateng, Lutz Asmus, Matthias Degenhardt, Joerg Rosenberg

AAPS PharmSciTech· May 2018

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Physical stability of API/polymer-blend amorphous solid dispersions.
Kristin Lehmkemper, Samuel O Kyeremateng, Mareike Bartels, Matthias Degenhardt, Gabriele Sadowski

Eur J Pharm Biopharm· March 2018

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Influence of Low-Molecular-Weight Excipients on the Phase Behavior of PVPVA64 Amorphous Solid Dispersions.
Kristin Lehmkemper, Samuel O Kyeremateng, Matthias Degenhardt, Gabriele Sadowski

Pharm Res· January 2018

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Impact of Polymer Type and Relative Humidity on the Long-Term Physical Stability of Amorphous Solid Dispersions.
Kristin Lehmkemper, Samuel O Kyeremateng, Oliver Heinzerling, Matthias Degenhardt, Gabriele Sadowski

Mol Pharm· December 2017

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Long-Term Physical Stability of PVP- and PVPVA-Amorphous Solid Dispersions.
Kristin Lehmkemper, Samuel O Kyeremateng, Oliver Heinzerling, Matthias Degenhardt, Gabriele Sadowski

Mol Pharm· January 2017

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Efficient and economic HPLC performance qualification.
Lukas Kaminski, Matthias Degenhardt, Joachim Ermer, Claus Feussner, Heidemarie Höwer-Fritzen

J Pharm Biomed Anal· February 2010

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