Publications by authors named "Matthias Hebrok"

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Engineering synthetic suppressor T cells that execute locally targeted immunoprotective programs.
Nishith R Reddy, Hasna Maachi, Yini Xiao, Milos S Simic, Wei Yu, Matthias Hebrok

Science· December 2024

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nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer.
Audrey M Hendley, Sudipta Ashe, Atsushi Urano, Martin Ng, Tuan Anh Phu, Matthias Hebrok

bioRxiv· September 2024

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Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Hanane Laklai, Yekaterina A Miroshnikova, Michael W Pickup, Eric A Collisson, Grace E Kim, Matthias Hebrok

Nat Med· March 2024

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KRAS degradation averts PDAC chemoresistance.
Laura Leonhardt, Matthias Hebrok

Nat Cancer· March 2024

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Sox9 regulates alternative splicing and pancreatic beta cell function.
Sapna Puri, Hasna Maachi, Gopika Nair, Holger A Russ, Richard Chen, Matthias Hebrok

Nat Commun· January 2024

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Stem cell-derived islet therapy: is this the end of the beginning?
Veronica A Cochrane, Matthias Hebrok

Nat Rev Endocrinol· December 2023

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Species-specific roles for the MAFA and MAFB transcription factors in regulating islet β cell identity.
Jeeyeon Cha, Xin Tong, Emily M Walker, Tehila Dahan, Veronica A Cochrane, Matthias Hebrok

JCI Insight· August 2023

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Replenishable prevascularized cell encapsulation devices increase graft survival and function in the subcutaneous space.
Gauree S Chendke, Bhushan N Kharbikar, Sudipta Ashe, Gaetano Faleo, Julie B Sneddon, Matthias Hebrok

Bioeng Transl Med· July 2023

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Loss of ZNF148 enhances insulin secretion in human pancreatic β cells.
Eleonora de Klerk, Yini Xiao, Christopher H Emfinger, Mark P Keller, David I Berrios, Matthias Hebrok

JCI Insight· June 2023

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Role of Cell-Based Therapies in T2D.
Sudipta Ashe, Matthias Hebrok

Semin Nephrol· May 2023

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Multiplexed microfluidic platform for stem-cell derived pancreatic islet β cells.
Ishan Goswami, Eleonora de Klerk, Phichitpol Carnese, Matthias Hebrok, Kevin E Healy

Lab Chip· November 2022

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Development of a Beta Cell-Specific Expression Control Element for Recombinant Adeno-Associated Virus.
Sunghee Chai, Youngjin Kim, Feorillo Galivo, Craig Dorrell, Leslie Wakefield, Matthias Hebrok

Hum Gene Ther· August 2022

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Pancreatic β-Cell Development and Regeneration.
Natanya Kerper, Sudipta Ashe, Matthias Hebrok

Cold Spring Harb Perspect Biol· May 2022

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β Cell-specific deletion of Zfp148 improves nutrient-stimulated β cell Ca2+ responses.
Christopher H Emfinger, Eleonora de Klerk, Kathryn L Schueler, Mary E Rabaglia, Donnie S Stapleton, Matthias Hebrok

JCI Insight· May 2022

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Development of a scalable method to isolate subsets of stem cell-derived pancreatic islet cells.
Audrey V Parent, Sudipta Ashe, Gopika G Nair, Mei-Lan Li, Jessica Chavez, Matthias Hebrok

Stem Cell Reports· April 2022

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Stem Cell-Based Clinical Trials for Diabetes Mellitus.
Eleonora de Klerk, Matthias Hebrok

Front Endocrinol (Lausanne)· December 2021

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Superporous agarose scaffolds for encapsulation of adult human islets and human stem-cell-derived β cells for intravascular bioartificial pancreas applications.
Rebecca Shaheen, Rachel E Gurlin, Rebecca Gologorsky, Charles Blaha, Pujita Munnangi, Matthias Hebrok

J Biomed Mater Res A· December 2021

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Mutations and variants of ONECUT1 in diabetes.
Anne Philippi, Sandra Heller, Ivan G Costa, Valérie Senée, Markus Breunig, Matthias Hebrok

Nat Med· November 2021

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Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation.
Sandra Heller, Zhijian Li, Qiong Lin, Ryan Geusz, Markus Breunig, Matthias Hebrok

Commun Biol· November 2021

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Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection.
Audrey V Parent, Gaetano Faleo, Jessica Chavez, Michael Saxton, David I Berrios, Matthias Hebrok

Cell Rep· August 2021

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Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree.
Audrey M Hendley, Arjun A Rao, Laura Leonhardt, Sudipta Ashe, Jennifer A Smith, Matthias Hebrok

Elife· May 2021

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Non-xenogeneic expansion and definitive endoderm differentiation of human pluripotent stem cells in an automated bioreactor.
Elena F Jacobson, Zijing Chen, Demetrios M Stoukides, Gopika G Nair, Matthias Hebrok

Biotechnol Bioeng· February 2021

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Emerging routes to the generation of functional β-cells for diabetes mellitus cell therapy.
Gopika G Nair, Emmanuel S Tzanakakis, Matthias Hebrok

Nat Rev Endocrinol· September 2020

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Loss of the transcription factor MAFB limits β-cell derivation from human PSCs.
Ronan Russell, Phichitpol P Carnese, Thomas G Hennings, Emily M Walker, Holger A Russ, Matthias Hebrok

Nat Commun· June 2020

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LIN28B Impairs the Transition of hESC-Derived β Cells from the Juvenile to Adult State.
Xin Zhou, Gopika G Nair, Holger A Russ, Cassandra D Belair, Mei-Lan Li, Matthias Hebrok

Stem Cell Reports· January 2020

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