Publications by authors named "Matthias Lauer"

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Scaling Down for Big Impact: Streamlined High-throughput Recombinant Adeno-associated Virus Production.
Philip Ohland, Miriam L Ferreiro, Jatina Schumacher, Linda E Franken, Catherine McKenzie, Matthias E Lauer

J Vis Exp· September 2025

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Exploring β-catenin and TCF4 interaction in complex environments by means of novel biosensing platform focal molography.
Philipp Cedro, Roman Popov, Maxime Karrer, Jean-Christophe Hau, Eric-André Kusznir, Matthias Lauer

PLoS One· September 2025

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Improved Recombinant Adeno-Associated Viral Vector Production via Molecular Evolution of the Viral Rep Protein.
Thomas Steininger, Veronika Öttl, Linda E Franken, Cornelius Frank, Philip Ohland, Matthias E Lauer

Int J Mol Sci· February 2025

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Investigations into mRNA Lipid Nanoparticles Shelf-Life Stability under Nonfrozen Conditions.
Anne-Gaëlle Reinhart, Anja Osterwald, Philippe Ringler, Yael Leiser, Matthias E Lauer

Mol Pharm· December 2023

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Propensities of Fatty Acid-Modified ASOs: Self-Assembly vs Albumin Binding.
Eric-André Kusznir, Jean-Christophe Hau, Michaela Portmann, Anne-Gaëlle Reinhart, Fabio Falivene, Matthias Lauer

Bioconjug Chem· May 2023

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Impact of non-ionizable lipids and phase mixing methods on structural properties of lipid nanoparticle formulations.
Anna Pratsinis, Yuchen Fan, Michaela Portmann, Michal Hammel, Ponien Kou, Matthias E Lauer

Int J Pharm· April 2023

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cryoWriter: a blotting free cryo-EM preparation system with a climate jet and cover-slip injector.
Luca Rima, Michael Zimmermann, Andri Fränkl, Thomas Clairfeuille, Matthias Lauer

Faraday Discuss· November 2022

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Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies.
Steffen Dickopf, Can Buldun, Vedran Vasic, Guy Georges, Carina Hage, Matthias E Lauer

Biol Chem· April 2022

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Evaluation of bovine milk extracellular vesicles for the delivery of locked nucleic acid antisense oligonucleotides.
Philip Grossen, Michaela Portmann, Erich Koller, Martina Duschmalé, Tanja Minz, Matthias E Lauer

Eur J Pharm Biopharm· January 2021

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Nanoindentation of Molecular Crystals: Lessons Learned from Aspirin.
Benjamin P A Gabriele, Craig J Williams, Matthias Eckhard Lauer, Brian Derby, Aurora J Cruz-Cabeza

Cryst Growth Des· September 2020

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DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity.
Claudio Sustmann, Steffen Dickopf, Jörg T Regula, Hubert Kettenberger, Michael Mølhøj, Matthias E Lauer

MAbs· June 2020

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Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody.
Martina Geiger, Kay-Gunnar Stubenrauch, Johannes Sam, Wolfgang F Richter, Gregor Jordan, Matthias E Lauer

Nat Commun· June 2020

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The Contorsbody, an antibody format for agonism: Design, structure, and function.
Guy J Georges, Stefan Dengl, Alexander Bujotzek, Friederike Hesse, Jens A A Fischer, Matthias E Lauer

Comput Struct Biotechnol J· May 2020

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Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy.
Ricardo Guerrero-Ferreira, Nicholas Mi Taylor, Ana-Andreea Arteni, Pratibha Kumari, Daniel Mona, Matthias E Lauer

Elife· December 2019

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Biochemical and biophysical characterization of purified native CD20 alone and in complex with rituximab and obinutuzumab.
Morgane Agez, Elodie Desuzinges Mandon, Thomas Iwema, Reto Gianotti, Florian Limani, Matthias Lauer

Sci Rep· September 2019

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Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes.
Sarah H Shahmoradian, Amanda J Lewis, Christel Genoud, Jürgen Hench, Tim E Moors, Matthias E Lauer

Nat Neurosci· July 2019

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Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.
Christina Claus, Claudia Ferrara, Wei Xu, Johannes Sam, Sabine Lang, Matthias Lauer

Sci Transl Med· June 2019

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Generation, Characterization, and Quantitative Bioanalysis of Drug/Anti-drug Antibody Immune Complexes to Facilitate Dedicated In Vivo Studies.
Eugenia Hoffmann, Gregor Jordan, Matthias Lauer, Philippe Ringler, Eric A Kusznir

Pharm Res· June 2019

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Highly flexible, IgG-shaped, trivalent antibodies effectively target tumor cells and induce T cell-mediated killing.
Steffen Dickopf, Matthias E Lauer, Philippe Ringler, Christian Spick, Peter Kern

Biol Chem· February 2019

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Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles.
Paula P Navarro, Christel Genoud, Daniel Castaño-Díez, Alexandra Graff-Meyer, Amanda J Lewis, Matthias E Lauer

Sci Rep· December 2018

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Cryo-EM structure of alpha-synuclein fibrils.
Ricardo Guerrero-Ferreira, Nicholas Mi Taylor, Daniel Mona, Philippe Ringler, Matthias E Lauer

Elife· July 2018

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A Miniaturized Extruder to Prototype Amorphous Solid Dispersions: Selection of Plasticizers for Hot Melt Extrusion.
Matthias E Lauer, Reto Maurer, Anne T De Paepe, Cordula Stillhart, Laurence Jacob

Pharmaceutics· May 2018

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Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs.
Friederike Plath, Philippe Ringler, Alexandra Graff-Meyer, Henning Stahlberg, Matthias E Lauer

MAbs· July 2016

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Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP.
Matthias E Lauer, Alexandra Graff-Meyer, Arne C Rufer, Cyrille Maugeais, Elisabeth von der Mark

J Struct Biol· May 2016

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Rapid assessment of homogeneity and stability of amorphous solid dispersions by atomic force microscopy--from bench to batch.
Matthias E Lauer, Monira Siam, Joseph Tardio, Susanne Page, Johannes H Kindt

Pharm Res· August 2013

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