Publications by authors named "Matthias Nees"

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Targeting fatty acid-binding protein 4: A therapeutic intersection of obesity and cancer via lipid metabolism.
Katarzyna Smolińska, Aleksandra Szopa, Piotr Dobrowolski, Jacek Dziedzic, Norbert Nowak, Matthias Nees

Prog Lipid Res· November 2025

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A Patient-Derived Scaffold-Based 3D Culture Platform for Head and Neck Cancer: Preserving Tumor Heterogeneity for Personalized Drug Testing.
Alinda Anameriç, Emilia Reszczyńska, Tomasz Stankiewicz, Adrian Andrzejczak, Andrzej Stepulak, Matthias Nees

Cells· October 2025

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Editor's Note: c-Myc Modulation and Acetylation Is a Key HDAC Inhibitor Target in Cancer.
Angela Nebbioso, Vincenzo Carafa, Mariarosaria Conte, Francesco Paolo Tambaro, Ciro Abbondanza, Matthias Nees

Clin Cancer Res· July 2025

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Loss of Sirtuin 7 impairs cell motility and proliferation and enhances S-phase cell arrest after 5-fluorouracil treatment in head and neck cancer.
Marta Halasa, Syeda Afshan, Anna Wawruszak, Agata Borkowska, Klaudia Brodaczewska, Matthias Nees

Sci Rep· January 2025

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Targeting the cancer cells and cancer-associated fibroblasts with next-generation FGFR inhibitors in prostate cancer co-culture models.
Syeda Afshan, Yu Gang Kim, Jesse Mattsson, Malin Åkerfelt, Pirkko Härkönen, Matthias Nees

Cancer Med· September 2024

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Surface Modification of Mesoporous Silica Nanoparticles as a Means to Introduce Inherent Cancer-Targeting Ability in a 3D Tumor Microenvironment.
Neeraj Prabhakar, Erica Långbacka, Ezgi Özliseli, Jesse Mattsson, Alaa Mahran, Matthias Nees

Small Sci· September 2024

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The Notch inhibitor, FLI-06, increases the chemosensitivity of head and neck Squamous cell carcinoma cells to taxanes-based treatment.
Arkadiusz Czerwonka, Joanna Kałafut, Shaoxia Wang, Alinda Anameric, Alicja Przybyszewska-Podstawka, Matthias Nees

Biomed Pharmacother· August 2024

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Assessment of targeted therapy opportunities in sinonasal cancers using patient-derived functional tumor models.
Noora Lehtinen, Janne Suhonen, Kiesha Rice, Eetu Välimäki, Mervi Toriseva, Matthias Nees

Transl Oncol· June 2024

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RUNX transcription factors are essential in maintaining epididymal epithelial differentiation.
Mervi Toriseva, Ida Björkgren, Arttu Junnila, Arfa Mehmood, Jesse Mattsson, Matthias Nees

Cell Mol Life Sci· April 2024

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Optimization of a Three-Dimensional Culturing Method for Assessing the Impact of Cisplatin on Notch Signaling in Head and Neck Squamous Cell Carcinoma (HNSCC).
Alinda Anameriç, Arkadiusz Czerwonka, Matthias Nees

Cancers (Basel)· November 2023

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Modulation of Notch Signaling by Small-Molecular Compounds and Its Potential in Anticancer Studies.
Arkadiusz Czerwonka, Joanna Kałafut, Matthias Nees

Cancers (Basel)· September 2023

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Evaluation of the anticancer activity of RIN-1, a Notch signaling modulator, in head and neck squamous cell carcinoma.
Arkadiusz Czerwonka, Joanna Kałafut, Shaoxia Wang, Alinda Anameric, Alicja Przybyszewska-Podstawka, Matthias Nees

Sci Rep· August 2023

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The effect of matrices on the gene expression profile of patient-derived head and neck carcinoma cells for in vitro therapy testing.
Aini Hyytiäinen, Katja Korelin, Mervi Toriseva, Tommy Wilkman, Satu Kainulainen, Matthias Nees

Cancer Cell Int· July 2023

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Increased Expression and Altered Cellular Localization of Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) Are Associated with Prostate Cancer Progression.
Lan Yu, Mervi Toriseva, Syeda Afshan, Mario Cangiano, Vidal Fey, Matthias Nees

Cancers (Basel)· January 2022

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Shooting at Moving and Hidden Targets-Tumour Cell Plasticity and the Notch Signalling Pathway in Head and Neck Squamous Cell Carcinomas.
Joanna Kałafut, Arkadiusz Czerwonka, Alinda Anameriç, Alicja Przybyszewska-Podstawka, Julia O Misiorek, Matthias Nees

Cancers (Basel)· December 2021

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Potent Inhibitor of Human Trypsins from the Aeruginosin Family of Natural Products.
Muhammad N Ahmed, Matti Wahlsten, Jouni Jokela, Matthias Nees, Ulf-Håkan Stenman

ACS Chem Biol· November 2021

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CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer.
Nataliia Petruk, Sanni Tuominen, Malin Åkerfelt, Jesse Mattsson, Jouko Sandholm, Matthias Nees

Sci Rep· March 2021

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Context Matters: NOTCH Signatures and Pathway in Cancer Progression and Metastasis.
Julia O Misiorek, Alicja Przybyszewska-Podstawka, Joanna Kałafut, Beata Paziewska, Katarzyna Rolle, Matthias Nees

Cells· January 2021

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Preparing biomedical students for the unknown: Some unusual challenges for students to help them understand the fundamentals of empirical research.
Adolfo Rivero-Müller, Matthias Nees

EMBO Rep· October 2019

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Inhibition of histone methyltransferase DOT1L silences ERα gene and blocks proliferation of antiestrogen-resistant breast cancer cells.
Giovanni Nassa, Annamaria Salvati, Roberta Tarallo, Valerio Gigantino, Elena Alexandrova, Matthias Nees

Sci Adv· February 2019

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Factors Affecting Intracellular Delivery and Release of Hydrophilic Versus Hydrophobic Cargo from Mesoporous Silica Nanoparticles on 2D and 3D Cell Cultures.
Diti Desai, Malin Åkerfelt, Neeraj Prabhakar, Mervi Toriseva, Tuomas Näreoja, Matthias Nees

Pharmaceutics· November 2018

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Increased HSF1 expression predicts shorter disease-specific survival of prostate cancer patients following radical prostatectomy.
Johanna K Björk, Ilmari Ahonen, Tuomas Mirtti, Andrew Erickson, Antti Rannikko, Matthias Nees

Oncotarget· July 2018

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Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer.
Virginia Murillo-Garzón, Irantzu Gorroño-Etxebarria, Malin Åkerfelt, Mikael Christer Puustinen, Lea Sistonen, Matthias Nees

Nat Commun· May 2018

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Quantitative Phenotypic Image Analysis of Three-Dimensional Organotypic Cultures.
Malin Åkerfelt, Mervi Toriseva, Matthias Nees

Methods Mol Biol· March 2018

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A high-content image analysis approach for quantitative measurements of chemosensitivity in patient-derived tumor microtissues.
Ilmari Ahonen, Malin Åkerfelt, Mervi Toriseva, Eva Oswald, Julia Schüler, Matthias Nees

Sci Rep· July 2017

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