Publications by authors named "Matthias P Machner"

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Genetic Approaches for Identifying and Characterizing Effectors in Bacterial Pathogens.
Nicole A Ellis, Matthias P Machner

Annu Rev Genet· November 2024

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The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling.
Stephanie S Lehman, Chad D Williamson, Trisha Tucholski, Nicole A Ellis, Sabrina Bouchard, Matthias P Machner

Cell Rep· April 2024

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A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes.
Nicole A Ellis, Kevin S Myers, Jessica Tung, Anne Davidson Ward, Kathryn Johnston, Matthias P Machner

Elife· December 2023

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A randomized multiplex CRISPRi-Seq approach for the identification of critical combinations of genes.
Nicole A Ellis, Kevin S Myers, Jessica Tung, Anne Davidson Ward, Kathryn Johnston, Matthias P Machner

bioRxiv· November 2023

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VpdC is a ubiquitin-activated phospholipase effector that regulates vacuole expansion during infection.
Xiao Li, D Eric Anderson, Yuen-Yan Chang, Michal Jarnik, Matthias P Machner

Proc Natl Acad Sci U S A· November 2022

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A Comprehensive Phenotypic Screening Strategy to Identify Modulators of Cargo Translocation by the Bacterial Type IVB Secretion System.
Eric Cheng, Dorjbal Dorjsuren, Stephanie Lehman, Charles L Larson, Steven A Titus, Matthias P Machner

mBio· April 2022

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A multiplex CRISPR interference tool for virulence gene interrogation in Legionella pneumophila.
Nicole A Ellis, Byoungkwan Kim, Jessica Tung, Matthias P Machner

Commun Biol· February 2021

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Structural insight into the membrane targeting domain of the Legionella  deAMPylase SidD.
Igor Tascón, Xiao Li, María Lucas, D'anna Nelson, Ander Vidaurrazaga, Matthias P Machner

PLoS Pathog· August 2020

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The kinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Pei-Chung Lee, Ksenia Beyrakhova, Caishuang Xu, Michal T Boniecki, Mitchell H Lee, Matthias P Machner

Proc Natl Acad Sci U S A· June 2020

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Editorial: Biology and Pathogenesis of .
Hayley J Newton, Elizabeth L Hartland, Matthias P Machner

Front Cell Infect Microbiol· September 2019

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The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection.
Pei-Chung Lee, Matthias P Machner

Cell Host Microbe· September 2018

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RavN is a member of a previously unrecognized group of Legionella pneumophila E3 ubiquitin ligases.
Yi-Han Lin, María Lucas, Timothy R Evans, Guillermo Abascal-Palacios, Alexandra G Doms, Matthias P Machner

PLoS Pathog· February 2018

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Legionella effector AnkX interacts with host nuclear protein PLEKHN1.
Xiaobo Yu, Rebecca R Noll, Barbara P Romero Dueñas, Samual C Allgood, Kristi Barker, Matthias P Machner

BMC Microbiol· January 2018

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Molecular mechanism for the subversion of the retromer coat by the effector RidL.
Miguel Romano-Moreno, Adriana L Rojas, Chad D Williamson, David C Gershlick, María Lucas, Matthias P Machner

Proc Natl Acad Sci U S A· December 2017

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Exploitation of the host cell ubiquitin machinery by microbial effector proteins.
Yi-Han Lin, Matthias P Machner

J Cell Sci· June 2017

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Infection biology: Small RNA with a large impact.
Matthias P Machner, Gisela Storz

Nature· January 2016

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Host Cell-catalyzed S-Palmitoylation Mediates Golgi Targeting of the Legionella Ubiquitin Ligase GobX.
Yi-Han Lin, Alexandra G Doms, Eric Cheng, Byoungkwan Kim, Timothy R Evans, Matthias P Machner

J Biol Chem· October 2015

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Host-pathogen interaction profiling using self-assembling human protein arrays.
Xiaobo Yu, Kimberly B Decker, Kristi Barker, M Ramona Neunuebel, Justin Saul, Matthias P Machner

J Proteome Res· April 2015

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Ingenious strategies of microbial pathogens.
Naomi S Morrissette, Matthias P Machner

Mol Biol Cell· March 2015

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Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5.
María Lucas, Andrew H Gaspar, Chiara Pallara, Adriana Lucely Rojas, Juan Fernández-Recio, Matthias P Machner

Proc Natl Acad Sci U S A· August 2014

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A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi.
Gerald R V Hammond, Matthias P Machner, Tamas Balla

J Cell Biol· April 2014

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VipD is a Rab5-activated phospholipase A1 that protects Legionella pneumophila from endosomal fusion.
Andrew H Gaspar, Matthias P Machner

Proc Natl Acad Sci U S A· March 2014

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Structural basis for Rab1 de-AMPylation by the Legionella pneumophila effector SidD.
Yang Chen, Igor Tascón, M Ramona Neunuebel, Chiara Pallara, Jacqueline Brady, Matthias P Machner

PLoS Pathog· December 2013

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Targeting of the small GTPase Rab6A' by the Legionella pneumophila effector LidA.
Yang Chen, Matthias P Machner

Infect Immun· June 2013

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The taming of a Rab GTPase by Legionella pneumophila.
M Ramona Neunuebel, Matthias P Machner

Small GTPases· April 2013

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