Publications by authors named "Matthias Scheunemann"

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Radiosynthesis and Preclinical Evaluation of an F-Labeled Triazolopyridopyrazine-Based Inhibitor for Neuroimaging of the Phosphodiesterase 2A (PDE2A).
Barbara Wenzel, Stefan R Fritzsche, Magali Toussaint, Detlef Briel, Klaus Kopka, Matthias Scheunemann

Pharmaceuticals (Basel)· October 2022

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Structure-Based Design, Optimization, and Development of [F]LU13: A Novel Radioligand for Cannabinoid Receptor Type 2 Imaging in the Brain with PET.
Daniel Gündel, Winnie Deuther-Conrad, Lea Ueberham, Sarandeep Kaur, Elina Otikova, Matthias Scheunemann

J Med Chem· July 2022

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Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain.
Oliver Clauß, Linda Schäker-Hübner, Barbara Wenzel, Magali Toussaint, Winnie Deuther-Conrad, Matthias Scheunemann

Pharmaceuticals (Basel)· March 2022

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Challenges on Cyclic Nucleotide Phosphodiesterases Imaging with Positron Emission Tomography: Novel Radioligands and (Pre-)Clinical Insights since 2016.
Susann Schröder, Matthias Scheunemann, Barbara Wenzel, Peter Brust

Int J Mol Sci· April 2021

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Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine- Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography.
Rien Ritawidya, Barbara Wenzel, Rodrigo Teodoro, Magali Toussaint, Mathias Kranz, Matthias Scheunemann

Molecules· November 2019

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Synthesis and In Vitro Evaluation of 8-Pyridinyl-Substituted Benzo[]imidazo[2,1-][1,2,4]triazines as Phosphodiesterase 2A Inhibitors.
Rien Ritawidya, Friedrich-Alexander Ludwig, Detlef Briel, Peter Brust, Matthias Scheunemann

Molecules· July 2019

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Synthesis and radiofluorination of novel fluoren-9-one based derivatives for the imaging of α7 nicotinic acetylcholine receptor with PET.
Rodrigo Teodoro, Matthias Scheunemann, Barbara Wenzel, Dan Peters, Winnie Deuther-Conrad

Bioorg Med Chem Lett· May 2018

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Investigation of an F-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A.
Susann Schröder, Barbara Wenzel, Winnie Deuther-Conrad, Rodrigo Teodoro, Mathias Kranz, Matthias Scheunemann

Molecules· March 2018

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PET imaging of α nicotinic acetylcholine receptors: a comparative study of [F]ASEM and [F]DBT-10 in nonhuman primates, and further evaluation of [F]ASEM in humans.
Ansel T Hillmer, Songye Li, Ming-Qiang Zheng, Matthias Scheunemann, Shu-Fei Lin

Eur J Nucl Med Mol Imaging· June 2017

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Radiosynthesis of (S)-[F]T1: The first PET radioligand for molecular imaging of α3β4 nicotinic acetylcholine receptors.
Jiradanai Sarasamkan, Steffen Fischer, Winnie Deuther-Conrad, Friedrich-Alexander Ludwig, Matthias Scheunemann

Appl Radiat Isot· June 2017

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Radiosynthesis and biological evaluation of the new PDE10A radioligand [ F]AQ28A.
Sally Wagner, Rodrigo Teodoro, Winnie Deuther-Conrad, Mathias Kranz, Matthias Scheunemann

J Labelled Comp Radiopharm· January 2017

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Varying Chirality Across Nicotinic Acetylcholine Receptor Subtypes: Selective Binding of Quinuclidine Triazole Compounds.
Jiradanai Sarasamkan, Matthias Scheunemann, Nattayaporn Apaijai, Siripong Palee, Warisara Parichatikanond

ACS Med Chem Lett· October 2016

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Tos-Nos-Mos: Synthesis of different aryl sulfonate precursors for the radiosynthesis of the alpha7 nicotinic acetylcholine receptor radioligand [(18)F]NS14490.
Sven Rötering, Matthias Scheunemann, Robert Günther, Reik Löser, Achim Hiller

Appl Radiat Isot· August 2016

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Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012.
Susann Schröder, Barbara Wenzel, Winnie Deuther-Conrad, Matthias Scheunemann, Peter Brust

Molecules· May 2016

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PET imaging evaluation of [(18)F]DBT-10, a novel radioligand specific to α7 nicotinic acetylcholine receptors, in nonhuman primates.
Ansel T Hillmer, Ming-Qiang Zheng, Songye Li, Matthias Scheunemann, Shu-fei Lin

Eur J Nucl Med Mol Imaging· March 2016

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Development of highly potent phosphodiesterase 10A (PDE10A) inhibitors: Synthesis and in vitro evaluation of 1,8-dipyridinyl- and 1-pyridinyl-substituted imidazo[1,5-a]quinoxalines.
Sally Wagner, Matthias Scheunemann, Karolin Dipper, Ute Egerland, Norbert Hoefgen

Eur J Med Chem· January 2016

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A Promising PET Tracer for Imaging of α₇ Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand.
Rodrigo Teodoro, Matthias Scheunemann, Winnie Deuther-Conrad, Barbara Wenzel, Francesca Maria Fasoli

Molecules· October 2015

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New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure.
Claudia Barthel, Dietlind Sorger, Winnie Deuther-Conrad, Matthias Scheunemann, Stephanie Schweiger

Eur J Med Chem· July 2015

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Synthesis, 18F-Radiolabelling and Biological Characterization of Novel Fluoroalkylated Triazine Derivatives for in Vivo Imaging of Phosphodiesterase 2A in Brain via Positron Emission Tomography.
Susann Schröder, Barbara Wenzel, Winnie Deuther-Conrad, Rodrigo Teodoro, Ute Egerland, Matthias Scheunemann

Molecules· May 2015

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Imaging of α7 nicotinic acetylcholine receptors in brain and cerebral vasculature of juvenile pigs with [(18)F]NS14490.
Sven Rötering, Winnie Deuther-Conrad, Paul Cumming, Cornelius K Donat, Matthias Scheunemann

EJNMMI Res· August 2014

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Fluorine-containing 6,7-dialkoxybiaryl-based inhibitors for phosphodiesterase 10 A: synthesis and in vitro evaluation of inhibitory potency, selectivity, and metabolism.
Gregor Schwan, Ghadir Barbar Asskar, Norbert Höfgen, Lenka Kubicova, Uta Funke, Matthias Scheunemann

ChemMedChem· July 2014

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Radiosynthesis and first evaluation in mice of [(18)F]NS14490 for molecular imaging of α7 nicotinic acetylcholine receptors.
Sven Rötering, Matthias Scheunemann, Steffen Fischer, Achim Hiller, Dan Peters

Bioorg Med Chem· May 2013

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Radiosynthesis and Radiotracer Properties of a 7-(2-[18F]Fluoroethoxy)-6-methoxypyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET.
Uta Funke, Winnie Deuther-Conrad, Gregor Schwan, Aurélie Maisonial, Matthias Scheunemann

Pharmaceuticals (Basel)· February 2012

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A ¹⁸F-labeled fluorobutyl-substituted spirocyclic piperidine derivative as a selective radioligand for PET Imaging of sigma₁ receptors.
Aurélie Maisonial, Eva Grosse Maestrup, Steffen Fischer, Achim Hiller, Matthias Scheunemann

ChemMedChem· August 2011

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Molecular imaging of σ receptors: synthesis and evaluation of the potent σ1 selective radioligand [18F]fluspidine.
Steffen Fischer, Christian Wiese, Eva Grosse Maestrup, Achim Hiller, Winnie Deuther-Conrad, Matthias Scheunemann

Eur J Nucl Med Mol Imaging· March 2011

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