Publications by authors named "Matthias Wirth"

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Genetic alterations of SENP6 in multiple myeloma disrupt genome and proteome stability, sensitizing to proteasome inhibition.
Frederik Herzberg, Michael Korenkov, Konstandina Isaakidis, Chuanbing Zang, Matthias Wirth

Haematologica· December 2025

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The Histone Modifier KANSL2 Is an Actionable Biomarker in Multiple Myeloma.
Kaiting Jiang, Marieluise Kirchner, Frederik Herzberg, Yan Zhao, Amelie Gasper, Matthias Wirth

Mol Cancer Ther· December 2025

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Pan-ERBB Inhibitors Synergize With KRAS Inhibitors in Rectal Cancer.
Jonas Buchloh, Melanie Spitzner, Hauke Zimmermann, Xin Fang, Constanza Tapia Contreras, Matthias Wirth

United European Gastroenterol J· November 2025

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The histone modifier KANSL2 is an actionable biomarker in multiple myeloma.
Kaiting Jiang, Marieluise Kirchner, Frederik Herzberg, Yan Zhao, Amelie Gasper, Matthias Wirth

Mol Cancer Ther· November 2025

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Targeting Mutual Dependence of Phosphatidylinositol-3-Kinase α/δ and Small Ubiquitin-Like Modifier Signaling in Pancreatic Cancer.
Hazal Köse, Christian Schneeweis, Philipp Putze, Constanza Tapia Contreras, Laura Ferreiro, Matthias Wirth

Gastroenterology· October 2025

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Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform.
Selen Selcen, Lena Wieland, Tiago De Oliveira, Michael Ghadimi, Lena-Christin Conradi, Matthias Wirth

Cell Death Discov· August 2025

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Author Correction: Segment Anything for Microscopy.
Anwai Archit, Luca Freckmann, Sushmita Nair, Nabeel Khalid, Paul Hilt, Matthias Wirth

Nat Methods· July 2025

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Segment Anything for Microscopy.
Anwai Archit, Luca Freckmann, Sushmita Nair, Nabeel Khalid, Paul Hilt, Matthias Wirth

Nat Methods· March 2025

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KRAS -inhibitor-based combination therapies for pancreatic cancer: insights from drug screening.
Constanza Tapia Contreras, Jonas Dominik Falke, Dana-Magdalena Seifert, Carolin Schneider, Lukas Krauß, Matthias Wirth

Mol Oncol· February 2025

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A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction.
Carolin Schneider, Jorina Hilbert, Franziska Genevaux, Stefanie Höfer, Lukas Krauß, Matthias Wirth

Adv Sci (Weinh)· August 2024

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Author Correction: Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
Pawel K Mazur, Alexander Herner, Stephano S Mello, Matthias Wirth, Simone Hausmann

Nat Med· July 2024

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A Hypoxia-Epigenetics Axis Drives EMT in Pancreatic Cancer.
Matthias Wirth, Günter Schneider

Cancer Res· June 2024

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Corrigendum to "A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer" [Bioorgan. Chem. 119 (2022) 105505].
Svenja Lier, Andreas Sellmer, Felix Orben, Stephanie Heinzlmeir, Lukas Krauß, Matthias Wirth

Bioorg Chem· May 2024

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Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.
Judith Dönig, Hannah Mende, Jimena Davila Gallesio, Kristina Wagner, Paul Hotz, Matthias Wirth

Nat Commun· December 2023

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Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.
Le Zhang, Matthias Wirth, Upayan Patra, Jacob Stroh, Konstandina Isaakidis

EMBO Mol Med· September 2023

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Boosting T cell immunity against cytomegalovirus: a potential strategy combating human aging and age-related diseases.
Matthias Wirth, Walburgis Brenner, Oliver H Krämer

Signal Transduct Target Ther· September 2023

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NOXA Accentuates Apoptosis Induction by a Novel Histone Deacetylase Inhibitor.
Ramy Ashry, Al-Hassan M Mustafa, Kristin Hausmann, Michael Linnebacher, Susanne Strand, Matthias Wirth

Cancers (Basel)· July 2023

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SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.
Guus J J E Heynen, Francis Baumgartner, Michael Heider, Upayan Patra, Maximilian Holz, Matthias Wirth

Blood Adv· February 2023

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Small-molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy.
Uta M Demel, Matthias Wirth, Schayan Yousefian, Le Zhang, Konstandina Isaakidis

Haematologica· February 2023

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AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer.
Christian Schneeweis, Sandra Diersch, Zonera Hassan, Lukas Krauß, Carolin Schneider, Matthias Wirth

Cell Mol Life Sci· December 2022

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The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma.
Carmen Paulmann, Ria Spallek, Oleksandra Karpiuk, Michael Heider, Isabell Schäffer, Matthias Wirth

EMBO J· October 2022

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CRISPR Activation/Interference Screen to Identify Genetic Networks in HDAC-Inhibitor-Resistant Cells.
Paul Jung, Laura Schmalbrock, Matthias Wirth

Methods Mol Biol· October 2022

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Epigenetic drug screening defines a PRMT5 inhibitor-sensitive pancreatic cancer subtype.
Felix Orben, Katharina Lankes, Christian Schneeweis, Zonera Hassan, Hannah Jakubowsky, Matthias Wirth

JCI Insight· May 2022

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Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer.
Uta M Demel, Marlitt Böger, Schayan Yousefian, Corinna Grunert, Le Zhang, Matthias Wirth

J Clin Invest· May 2022

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Indirect targeting of MYC sensitizes pancreatic cancer cells to mechanistic target of rapamycin (mTOR) inhibition.
Christian Schneeweis, Zonera Hassan, Katja Ascherl, Matthias Wirth, Stella Koutsouli

Cancer Commun (Lond)· April 2022

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