Publications by authors named "Matthieu Drouyer"

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Enhanced AAV transduction across preclinical CNS models: A comparative study in human brain organoids with cross-species evaluations.
Matthieu Drouyer, Jessica Merjane, Teodora Nedelkoska, Adrian Westhaus, Suzanne Scott

Mol Ther Nucleic Acids· September 2024

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Novel AAV variants with improved tropism for human Schwann cells.
Matthieu Drouyer, Tak-Ho Chu, Elodie Labit, Florencia Haase, Renina Gale Navarro

Mol Ther Methods Clin Dev· June 2024

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Development of CNS tropic AAV1-like variants with reduced liver-targeting following systemic administration in mice.
Matthieu Drouyer, Jessica Merjane, Deborah Nazareth, Maddison Knight, Suzanne Scott

Mol Ther· March 2024

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PAK6-mediated phosphorylation of PPP2R2C regulates LRRK2-PP2A complex formation.
Lucia Iannotta, Marco Emanuele, Giulia Favetta, Giulia Tombesi, Laurine Vandewynckel, Matthieu Drouyer

Front Mol Neurosci· December 2023

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Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8.
Marti Cabanes-Creus, Renina Gale Navarro, Erhua Zhu, Grober Baltazar, Sophia H Y Liao, Matthieu Drouyer

Mol Ther Methods Clin Dev· March 2022

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A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively.
Antoine Marchand, Alessia Sarchione, Panagiotis S Athanasopoulos, Hélène Bauderlique-Le Roy, Liesel Goveas, Matthieu Drouyer

Cells· March 2022

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Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation.
Matthieu Drouyer, Marc F Bolliger, Evy Lobbestael, Chris Van den Haute, Marco Emanuele

Neurobiol Dis· September 2021

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Single amino acid insertion allows functional transduction of murine hepatocytes with human liver tropic AAV capsids.
Marti Cabanes-Creus, Renina Gale Navarro, Sophia H Y Liao, Grober Baltazar, Matthieu Drouyer

Mol Ther Methods Clin Dev· June 2021

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Restoring the natural tropism of AAV2 vectors for human liver.
Marti Cabanes-Creus, Claus V Hallwirth, Adrian Westhaus, Boaz H Ng, Sophia H Y Liao, Matthieu Drouyer

Sci Transl Med· September 2020

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Attenuation of Heparan Sulfate Proteoglycan Binding Enhances Transduction of Human Primary Hepatocytes with AAV2.
Marti Cabanes-Creus, Adrian Westhaus, Renina Gale Navarro, Grober Baltazar, Erhua Zhu, Matthieu Drouyer

Mol Ther Methods Clin Dev· June 2020

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LRRK2 Phosphorylation, More Than an Epiphenomenon.
Antoine Marchand, Matthieu Drouyer, Alessia Sarchione, Marie-Christine Chartier-Harlin, Jean-Marc Taymans

Front Neurosci· June 2020

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High-Throughput , and Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction.
Adrian Westhaus, Marti Cabanes-Creus, Arkadiusz Rybicki, Grober Baltazar, Renina Gale Navarro, Matthieu Drouyer

Hum Gene Ther· May 2020

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Investigating the neuroprotective effect of AAV-mediated β-synuclein overexpression in a transgenic model of synucleinopathy.
Dorian Sargent, Dominique Bétemps, Matthieu Drouyer, Jérémy Verchere, Damien Gaillard

Sci Rep· December 2018

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GTP binding regulates cellular localization of Parkinson's disease-associated LRRK2.
Marian Blanca Ramírez, Antonio Jesús Lara Ordóñez, Elena Fdez, Jesús Madero-Pérez, Adriano Gonnelli, Matthieu Drouyer

Hum Mol Genet· July 2017

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LRRK2 detection in human biofluids: potential use as a Parkinson's disease biomarker?
Jean-Marc Taymans, Eugénie Mutez, Matthieu Drouyer, William Sibran, Marie-Christine Chartier-Harlin

Biochem Soc Trans· February 2017

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