Publications by authors named "Matthijs D Linssen"

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Development of Clinical-Grade Durvalumab-680LT and Nivolumab-800CW for Multispectral Fluorescent Imaging of the PD-1/PD-L1 Axis of the Immune Checkpoint Pathway.
Henrik K Huizinga, Wouter T R Hooghiemstra, Matthijs D Linssen, Derk P Allersma, Bahez Gareb

Pharmaceuticals (Basel)· October 2025

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Publisher Correction: Personalized, autologous neoantigen-specific T cell therapy in metastatic melanoma: a phase 1 trial.
Jessica S W Borgers, Divya Lenkala, Victoria Kohler, Emily K Jackson, Matthijs D Linssen

Nat Med· September 2025

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Personalized, autologous neoantigen-specific T cell therapy in metastatic melanoma: a phase 1 trial.
Jessica S W Borgers, Divya Lenkala, Victoria Kohler, Emily K Jackson, Matthijs D Linssen

Nat Med· March 2025

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Fluorescently labelled vedolizumab to visualise drug distribution and mucosal target cells in inflammatory bowel disease.
Ruben Y Gabriëls, Anne M van der Waaij, Matthijs D Linssen, Michael Dobosz, Pia Volkmer

Gut· August 2024

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EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial.
Jaron G de Wit, Jasper Vonk, Floris J Voskuil, Sebastiaan A H J de Visscher, Kees-Pieter Schepman, Matthijs D Linssen

Nat Commun· August 2023

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Epidermal Growth Factor Receptor-Targeted Fluorescence Molecular Imaging for Postoperative Lymph Node Assessment in Patients with Oral Cancer.
Jasper Vonk, Jaron G de Wit, Floris J Voskuil, Yang Hang Tang, Wouter T R Hooghiemstra, Matthijs D Linssen

J Nucl Med· May 2022

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Development and Characterisation of Antibody-Based Optical Imaging Probes for Inflammatory Bowel Disease.
Matthijs David Linssen, Wouter Tjerk Rudolph Hooghiemstra, Annelies Jorritsma-Smit, Derk Pieter Allersma, Gerard Dijkstra

Pharmaceuticals (Basel)· September 2021

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Identification and Validation of Esophageal Squamous Cell Carcinoma Targets for Fluorescence Molecular Endoscopy.
Xiaojuan Zhao, Qingfeng Huang, Marjory Koller, Matthijs D Linssen, Wouter T R Hooghiemstra

Int J Mol Sci· August 2021

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Fluorescence-guided imaging for resection margin evaluation in head and neck cancer patients using cetuximab-800CW: A quantitative dose-escalation study.
Floris Jan Voskuil, Steven Jakob de Jongh, Wouter Tjerk Rudolph Hooghiemstra, Matthijs David Linssen, Pieter Jan Steinkamp

Theranostics· May 2021

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Fluorescence-Guided Visualization of Soft-Tissue Sarcomas by Targeting Vascular Endothelial Growth Factor A: A Phase 1 Single-Center Clinical Trial.
Pieter J Steinkamp, Bobby K Pranger, Mei-Fang Li, Matthijs D Linssen, Floris J Voskuil

J Nucl Med· March 2021

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Feasibility of ex vivo fluorescence imaging of angiogenesis in (non-) culprit human carotid atherosclerotic plaques using bevacizumab-800CW.
Lydian A Huisman, Pieter J Steinkamp, Jan-Luuk Hillebrands, Clark J Zeebregts, Matthijs D Linssen

Sci Rep· February 2021

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Back-Table Fluorescence-Guided Imaging for Circumferential Resection Margin Evaluation Using Bevacizumab-800CW in Patients with Locally Advanced Rectal Cancer.
Steven J de Jongh, Jolien J J Tjalma, Marjory Koller, Matthijs D Linssen, Jasper Vonk

J Nucl Med· May 2020

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Quantitative fluorescence endoscopy: an innovative endoscopy approach to evaluate neoadjuvant treatment response in locally advanced rectal cancer.
Jolien J J Tjalma, Marjory Koller, Matthijs D Linssen, Elmire Hartmans, Steven J de Jongh

Gut· March 2020

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Roadmap for the Development and Clinical Translation of Optical Tracers Cetuximab-800CW and Trastuzumab-800CW.
Matthijs D Linssen, Eva J Ter Weele, Derk P Allersma, Marjolijn N Lub-de Hooge, Gooitzen M van Dam

J Nucl Med· March 2019

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Near-infrared fluorescence molecular endoscopy detects dysplastic oesophageal lesions using topical and systemic tracer of vascular endothelial growth factor A.
Wouter B Nagengast, Elmire Hartmans, Pilar B Garcia-Allende, Frans T M Peters, Matthijs D Linssen

Gut· January 2019

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Potential Red-Flag Identification of Colorectal Adenomas with Wide-Field Fluorescence Molecular Endoscopy.
Elmire Hartmans, Jolien J J Tjalma, Matthijs D Linssen, Pilar Beatriz Garcia Allende, Marjory Koller

Theranostics· January 2019

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Implementation and benchmarking of a novel analytical framework to clinically evaluate tumor-specific fluorescent tracers.
Marjory Koller, Si-Qi Qiu, Matthijs D Linssen, Liesbeth Jansen, Wendy Kelder

Nat Commun· September 2018

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Noninvasive optical and nuclear imaging of Staphylococcus-specific infection with a human monoclonal antibody-based probe.
Francisco Romero Pastrana, John M Thompson, Marjolein Heuker, Hedzer Hoekstra, Carly A Dillen, Matthijs D Linssen

Virulence· January 2018

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Tumor-Specific Uptake of Fluorescent Bevacizumab-IRDye800CW Microdosing in Patients with Primary Breast Cancer: A Phase I Feasibility Study.
Laetitia E Lamberts, Maximillian Koch, Johannes S de Jong, Arthur L L Adams, Jürgen Glatz, Matthijs D Linssen

Clin Cancer Res· June 2017

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Tyrosine kinase inhibitor induced growth factor receptor upregulation enhances the efficacy of near-infrared targeted photodynamic therapy in esophageal adenocarcinoma cell lines.
Elmire Hartmans, Matthijs D Linssen, Claire Sikkens, Afra Levens, Max J H Witjes

Oncotarget· May 2017

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Threshold Analysis and Biodistribution of Fluorescently Labeled Bevacizumab in Human Breast Cancer.
Maximilian Koch, Johannes S de Jong, Jürgen Glatz, Panagiotis Symvoulidis, Laetitia E Lamberts, Matthijs D Linssen

Cancer Res· February 2017

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Molecular fluorescence-guided surgery of peritoneal carcinomatosis of colorectal origin: a single-centre feasibility study.
Niels J Harlaar, Marjory Koller, Steven J de Jongh, Barbara L van Leeuwen, Patrick H Hemmer, Matthijs D Linssen

Lancet Gastroenterol Hepatol· December 2016

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Development, preclinical safety, formulation, and stability of clinical grade bevacizumab-800CW, a new near infrared fluorescent imaging agent for first in human use.
Eva J Ter Weele, Anton G T Terwisscha van Scheltinga, Matthijs D Linssen, Wouter B Nagengast, Ingo Lindner

Eur J Pharm Biopharm· July 2016

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