Publications by authors named "Matthijs Tibben"

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Reducing the Burden of Interaction Studies in Cancer Patients Using a Stable Isotopically Labeled Microtracer: A Proof-of-Concept Study with Alectinib.
Ma Ida Mohmaed Ali, Lisa T van der Heijden, Matthijs Tibben, Hilde Rosing, Raween Kalicharan

Clin Pharmacol Ther· November 2025

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Phase I Study of Sorafenib Combined with Gemcitabine and Carboplatin in Patients with Advanced Solid Tumors.
Daphne W M Voogd, Merel J J Lucassen, Ruud van der Noll, Sybrand W J Zielhuis, David Boss, Matthijs Tibben

Oncol Ther· June 2025

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Imatinib Desensitization After a Type IV Hypersensitivity Reaction in a Gastrointestinal Stromal Tumor Patient-A Case Report.
Maud B A van der Kleij, Tristan V M Bruijn, Raween W Kalicharan, Yannick S Elshot, Maxime C F Pilon, Matthijs M Tibben

Cancer Rep (Hoboken)· June 2025

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Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c.
Jamie Rijmers, Rolf W Sparidans, Manon Acda, Nancy H C Loos, Emmanouela Epeslidou, Matthijs Tibben

Mol Pharm· October 2024

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Interplay of Ritonavir-Boosted Oral Cabazitaxel with the Organic Anion-Transporting Polypeptide (OATP) Uptake Transporters and Carboxylesterase 1 in Mice.
Nancy H C Loos, Margarida L Ferreira Martins, Jamie Rijmers, Daniëlle de Jong, Maria C Lebre, Matthijs Tibben

Mol Pharm· April 2024

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Is Higher Docetaxel Clearance in Prostate Cancer Patients Explained by Higher CYP3A? An In Vivo Phenotyping Study with Midazolam.
Lisa T van der Heijden, Claire A Ribbers, Marit A C Vermunt, Dick Pluim, Manon Acda, Matthijs Tibben

J Clin Pharmacol· February 2024

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Coadministration of ABCB1/P-glycoprotein inhibitor elacridar improves tissue distribution of ritonavir-boosted oral cabazitaxel in mice.
Nancy H C Loos, Margarida L F Martins, Daniëlle de Jong, Maria C Lebre, Matthijs Tibben

Int J Pharm· January 2024

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A simple extemporaneous oral suspension of aprepitant yields sufficient pharmacokinetic exposure in children.
A Laura Nijstad, Evelien de Vos-Kerkhof, Catherine F Enters-Weijnen, Marianne D van de Wetering, Wim J E Tissing, Matthijs M Tibben

J Oncol Pharm Pract· June 2023

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Enhancement of the Oral Availability of Cabazitaxel Using the Cytochrome P450 3A (CYP3A) Inhibitor Ritonavir in Mice.
Nancy H C Loos, Margarida L F Martins, Daniëlle de Jong, Maria C Lebre, Matthijs Tibben

Mol Pharm· May 2023

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Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting.
A Laura Nijstad, Evelien de Vos-Kerkhof, Catherine F Enters-Weijnen, Marianne D van de Wetering, Wim J E Tissing, Matthijs M Tibben

Support Care Cancer· December 2022

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ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites.
Alejandra Martínez-Chávez, Nancy H C Loos, Maria C Lebre, Matthijs M Tibben, Hilde Rosing

Pharmacol Res· April 2022

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P-Glycoprotein (ABCB1/MDR1) Controls Brain Penetration and Intestinal Disposition of the PARP1/2 Inhibitor Niraparib.
Margarida L F Martins, Nancy H C Loos, Sümeyra Mucuk, Danielle de Jong, Maria C Lebre, Matthijs Tibben

Mol Pharm· December 2021

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Simultaneous quantification of abemaciclib and its active metabolites in human and mouse plasma by UHPLC-MS/MS.
Alejandra Martínez-Chávez, Matthijs M Tibben, Karen A M de Jong, Hilde Rosing, Alfred H Schinkel

J Pharm Biomed Anal· September 2021

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Development and validation of a combined liquid chromatography tandem-mass spectrometry assay for the quantification of aprepitant and dexamethasone in human plasma to support pharmacokinetic studies in pediatric patients.
A Laura Nijstad, Matthijs M Tibben, Abadi Gebretensae, Hilde Rosing, Evelien de Vos-Kerkhof

J Chromatogr B Analyt Technol Biomed Life Sci· May 2021

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The role of drug efflux and uptake transporters ABCB1 (P-gp), ABCG2 (BCRP) and OATP1A/1B and of CYP3A4 in the pharmacokinetics of the CDK inhibitor milciclib.
Alejandra Martínez-Chávez, Jelle Broeders, Maria C Lebre, Matthijs T Tibben, Hilde Rosing

Eur J Pharm Sci· April 2021

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Toxicological analysis of azide and cyanide for azide intoxications using gas chromatography.
Maaike A C Bruin, Douwe Dekker, Nikkie Venekamp, Matthijs Tibben, Hilde Rosing

Basic Clin Pharmacol Toxicol· March 2021

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Development and validation of an LC-MS/MS method for the quantitative analysis of milciclib in human and mouse plasma, mouse tissue homogenates and tissue culture medium.
Alejandra Martínez-Chávez, Matthijs M Tibben, Jelle Broeders, Hilde Rosing, Alfred H Schinkel

J Pharm Biomed Anal· October 2020

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P-glycoprotein (MDR1/ABCB1) controls brain accumulation and intestinal disposition of the novel TGF-β signaling pathway inhibitor galunisertib.
Wenlong Li, Matthijs Tibben, Yaogeng Wang, Maria C Lebre, Hilde Rosing

Int J Cancer· March 2020

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P-glycoprotein Limits Ribociclib Brain Exposure and CYP3A4 Restricts Its Oral Bioavailability.
Alejandra Martínez-Chávez, Stéphanie van Hoppe, Hilde Rosing, Maria C Lebre, Matthijs Tibben

Mol Pharm· September 2019

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Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry.
Alejandra Martínez-Chávez, Hilde Rosing, Michel Hillebrand, Matthijs Tibben, Alfred H Schinkel

Anal Bioanal Chem· August 2019

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A phase 0 clinical trial of novel candidate extended-release formulations of capecitabine.
Bart A W Jacobs, Jelte Meulenaar, Hilde Rosing, Dick Pluim, Matthijs M Tibben

Cancer Chemother Pharmacol· June 2016

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Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.
Suzanne Leijen, Sjaak A Burgers, Paul Baas, Dick Pluim, Matthijs Tibben

Invest New Drugs· February 2015

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A sensitive assay for the quantitative analysis of vinorelbine in mouse and human EDTA plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.
Carola W N Damen, Hilde Rosing, Matthijs M Tibben, Maria J van Maanen, Jurjen S Lagas

J Chromatogr B Analyt Technol Biomed Life Sci· June 2008

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The application of inductively coupled plasma mass spectrometry in clinical pharmacological oncology research.
Elke E M Brouwers, Matthijs Tibben, H Rosing, Jan H M Schellens, Jos H Beijnen

Mass Spectrom Rev· April 2008

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Determination of ruthenium originating from the investigational anti-cancer drug NAMI-A in human plasma ultrafiltrate, plasma, and urine by inductively coupled plasma mass spectrometry.
Elke E M Brouwers, Matthijs M Tibben, Hilde Rosing, Jan H M Schellens, Jos H Beijnen

Rapid Commun Mass Spectrom· June 2007

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