Publications by authors named "Max L Valenstein"

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Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2.
Martin S Taylor, Maggie Chen, Matthew Hancock, Maximilian Wranik, Bryant D Miller, Max L Valenstein

Science· November 2025

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Structural basis for the dynamic regulation of mTORC1 by amino acids.
Max L Valenstein, Maximilian Wranik, Pranav V Lalgudi, Karen Y Linde-Garelli, Yuri Choi

Nature· October 2025

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Polyglycine-mediated aggregation of FAM98B disrupts tRNA processing in GGC repeat disorders.
Jason Yang, Yunhan Xu, David R Ziehr, Martin S Taylor, Max L Valenstein

Science· July 2025

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Amino acids and KLHL22 do not activate mTORC1 via DEPDC5 degradation.
Max L Valenstein, Pranav V Lalgudi, Jibril F Kedir, Kendall J Condon, Anna Platzek

Nature· January 2025

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Rag-Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway.
Max L Valenstein, Pranav V Lalgudi, Xin Gu, Jibril F Kedir, Martin S Taylor

Proc Natl Acad Sci U S A· August 2024

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Author Correction: Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila.
Xin Gu, Patrick Jouandin, Pranav V Lalgudi, Rich Binari, Max L Valenstein

Nature· September 2022

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Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila.
Xin Gu, Patrick Jouandin, Pranav V Lalgudi, Rich Binari, Max L Valenstein

Nature· August 2022

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Structure of the nutrient-sensing hub GATOR2.
Max L Valenstein, Kacper B Rogala, Pranav V Lalgudi, Edward J Brignole, Xin Gu

Nature· July 2022

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Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases.
Kuang Shen, Max L Valenstein, Xin Gu, David M Sabatini

J Biol Chem· February 2019

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Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
Kuang Shen, Rick K Huang, Edward J Brignole, Kendall J Condon, Max L Valenstein

Nature· April 2018

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Graded Control of Microtubule Severing by Tubulin Glutamylation.
Max L Valenstein, Antonina Roll-Mecak

Cell· February 2016

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Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix.
Jessica A Brown, David Bulkley, Jimin Wang, Max L Valenstein, Therese A Yario

Nat Struct Mol Biol· July 2014

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Molecular basis for age-dependent microtubule acetylation by tubulin acetyltransferase.
Agnieszka Szyk, Alexandra M Deaconescu, Jeffrey Spector, Benjamin Goodman, Max L Valenstein

Cell· June 2014

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Formation of triple-helical structures by the 3'-end sequences of MALAT1 and MENβ noncoding RNAs.
Jessica A Brown, Max L Valenstein, Therese A Yario, Kazimierz T Tycowski, Joan A Steitz

Proc Natl Acad Sci U S A· November 2012

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