Publications by authors named "Max Nobis"

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A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma.
Alvaro Gonzalez Rajal, Kamila A Marzec, Rachael A McCloy, Max Nobis, Venessa Chin, Jordan F Hastings, Kaitao Lai, Marina Kennerson, William E Hughes, Vijesh Vaghjiani

Elife· May 2021

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Intestinal blood vessel-associated macrophages and gut-vascular barrier dysfunction in cirrhosis.
Lena Smets, Maria Francesca Viola, Markus Boesch, Jana Raman, Lukas Van Melkebeke, Max Nobis

Gut· December 2025

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Leukocytes have a heparan sulfate glycocalyx that regulates recruitment during psoriasis-like skin inflammation.
Megan J Priestley, Anna K Hains, Iashia Z Mulholland, Sam Spijkers-Shaw, Joshua C Müller, Max Nobis

Sci Signal· November 2025

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Murine vascular organoids are responsive and adaptable 3D systems with cellular heterogeneity and dynamic plasticity.
Sophie Guelfi, Krish Skandha Gopalan, Pieter Maene, Dorothy John Robbert, Carla Pallarés-Moratalla, Max Nobis

Sci Adv· October 2025

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Pharmacologic Inhibition of Glutamate Dehydrogenase 1 Improves Functional Recovery of Neuromuscular Junctions and Muscle Function in Duchenne Muscular Dystrophy.
Andreia Pereira-Nunes, Ummi Ammarah, Min Shang, Iris Charatsidou, Himal Sharma, Max Nobis

Am J Pathol· August 2025

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Targeting the NPY/NPY1R signaling axis in mutant p53-dependent pancreatic cancer impairs metastasis.
Cecilia R Chambers, Supitchaya Watakul, Peter Schofield, Anna E Howell, Jessie Zhu, Max Nobis

Sci Adv· March 2025

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Aspartate signalling drives lung metastasis via alternative translation.
Ginevra Doglioni, Juan Fernández-García, Sebastian Igelmann, Patricia Altea-Manzano, Arnaud Blomme, Max Nobis

Nature· February 2025

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Smad1/5 is acetylated in the dorsal aortae of the mouse embryo before the onset of blood flow, driving early arterial gene expression.
Margo Daems, Ljuba C Ponomarev, Rita Simoes-Faria, Max Nobis, Colinda L G J Scheele

Cardiovasc Res· December 2024

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Compression-dependent microtubule reinforcement enables cells to navigate confined environments.
Robert J Ju, Alistair D Falconer, Christanny J Schmidt, Marco A Enriquez Martinez, Kevin M Dean, Max Nobis

Nat Cell Biol· September 2024

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Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response.
Brooke A Pereira, Shona Ritchie, Cecilia R Chambers, Katie A Gordon, Astrid Magenau, Max Nobis

Sci Adv· July 2024

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Tumor Biomechanics Alters Metastatic Dissemination of Triple Negative Breast Cancer via Rewiring Fatty Acid Metabolism.
Elysse C Filipe, Sipiththa Velayuthar, Ashleigh Philp, Max Nobis, Sharissa L Latham

Adv Sci (Weinh)· June 2024

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Live Microscopy of Multicellular Spheroids with the Multimodal Near-Infrared Nanoparticles Reveals Differences in Oxygenation Gradients.
Angela C Debruyne, Irina A Okkelman, Nina Heymans, Cláudio Pinheiro, An Hendrix, Max Nobis

ACS Nano· May 2024

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An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade.
Diede Houbaert, Apostolos Panagiotis Nikolakopoulos, Kathryn A Jacobs, Odeta Meçe, Jana Roels, Max Nobis

Cell Rep· April 2024

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BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis.
Rebeca Uceda-Castro, Andreia S Margarido, Ji-Ying Song, Mark C de Gooijer, Hendrik A Messal, Max Nobis

Sci Adv· October 2023

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A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
Jessica L Chitty, Michelle Yam, Lara Perryman, Amelia L Parker, Joanna N Skhinas, Max Nobis

Nat Cancer· September 2023

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Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC.
Ebru Boslem, Saskia Reibe, Rodrigo Carlessi, Benoit Smeuninx, Surafel Tegegne, Max Nobis

Sci Adv· September 2023

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Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse.
James R W Conway, Sean C Warren, Young-Kyung Lee, Andrew T McCulloch, Astrid Magenau, Max Nobis

Sci Adv· April 2023

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Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma.
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Max Nobis

Sci Adv· March 2023

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Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis.
Michael Papanicolaou, Amelia L Parker, Michelle Yam, Elysse C Filipe, Sunny Z Wu, Max Nobis

Nat Commun· August 2022

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Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status.
Kendelle J Murphy, Daniel A Reed, Claire Vennin, James R W Conway, Max Nobis

Sci Adv· October 2021

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Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging.
Alessia Floerchinger, Kendelle J Murphy, Sharissa L Latham, Sean C Warren, Andrew T McCulloch, Max Nobis

Cell Rep· September 2021

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Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity.
Chenxu Yan, Tianshu Zeng, Kailun Lee, Max Nobis, Kim Loh

Nat Commun· May 2021

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Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress.
Noa Lamm, Mark N Read, Max Nobis, David Van Ly, Scott G Page

Nat Cell Biol· December 2020

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PtdIns(3,4,5)P-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.
Nuthasuda Srijakotre, Heng-Jia Liu, Max Nobis, Joey Man, Hon Yan Kelvin Yip

Proc Natl Acad Sci U S A· November 2020

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MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer.
Arcadi Cipponi, David L Goode, Justin Bedo, Mark J McCabe, Marina Pajic, Max Nobis

Science· June 2020

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