Publications by authors named "Max Thorwald"

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Chimpanzee and human ApoE isoforms differ in the stimulation of neurite differentiation consistent with structural predictions with relevance to brain development and aging.
Max A Thorwald, Mafalda Cacciottolo, Xiaogang Hou, Todd E Morgan, Caleb E Finch

J Alzheimers Dis· December 2025

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Basic Science and Pathogenesis.
Max A Thorwald, Jose A Godoy-Lugo, Marc Vermulst, Henry Jay Forman, Elizabeth Head

Alzheimers Dement· December 2025

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Form and function of actin impacts actin health and aging.
Maxim Averbukh, Hunter Nelson, Tiffany Wang, Caitlin M Lange, Athena Alcala, Max A Thorwald

bioRxiv· November 2025

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Air pollution decreases postsynaptic PSD-95 and NMDA receptor subunits in synaptosomes from mouse cerebral cortex.
Jose A Godoy-Lugo, Daniel Hicks, Salma Durra, Emma R Massey, Kristina Shkirkova, Max A Thorwald

Environ Pollut· October 2025

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Age-related declines in mitochondrial Prdx6 contribute to dysregulated muscle bioenergetics.
Jose Adan Arevalo, Dianna Xing, Roberto Garcia Leija, Max A Thorwald, Diana Daniela Moreno-Santillán

Redox Biol· October 2025

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Increase of brain Aβ peptides and secretase activity during normal aging in rodent and human.
Jose A Godoy-Lugo, Max A Thorwald, Elizabeth Head, Ashley L Gomm, Can Zhang

Geroscience· October 2025

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Beyond genes and environment: mapping biological stochasticity in aging.
Adam J Hruby, Gilberto Garcia, Max A Thorwald, Caleb E Finch, Joshua Johnson

Geroscience· June 2025

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Protection against APOE4-associated phenotypes with the longevity-promoting intervention 17α-estradiol in middle-aged male mice.
Cassandra J McGill, Amy Christensen, Wenjie Qian, Max A Thorwald, Jose Godoy Lugo

Commun Med (Lond)· June 2025

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The longevity effects of reduced IGF-1 signaling depend on the stability of the mitochondrial genome.
Sarah J Shemtov, Eric McGann, Lucy Carrillo, Sangmin Lee, Herbert Anson, Max A Thorwald

bioRxiv· June 2025

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Down syndrome with Alzheimer's disease brains have increased iron and associated lipid peroxidation consistent with ferroptosis.
Max A Thorwald, Jose A Godoy-Lugo, Elizabeth Kerstiens, Gilberto Garcia, Minhoo Kim

Alzheimers Dement· June 2025

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Chimpanzee and human ApoE isoforms differ in the stimulation of neurite differentiation consistent with structural predictions with relevance to brain development and aging.
Max A Thorwald, Mafalda Cacciottolo, Xiaogang Hou, Todd E Morgan, Caleb E Finch

bioRxiv· May 2025

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Activation of the muscle-to-brain axis ameliorates neurocognitive deficits in an Alzheimer's disease mouse model via enhancing neurotrophic and synaptic signaling.
Hash Brown Taha, Allison Birnbaum, Ian Matthews, Karel Aceituno, Jocelyne Leon, Max Thorwald

Geroscience· April 2025

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Iron chelation by oral deferoxamine treatment decreased brain iron and iron signaling proteins.
Max A Thorwald, Naomi S Sta Maria, Ararat Chakhoyan, Peggy A O'Day, Russell E Jacobs

J Alzheimers Dis· February 2025

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Down syndrome with Alzheimer's disease brains have increased iron and associated lipid peroxidation consistent with ferroptosis.
Max A Thorwald, Jose A Godoy-Lugo, Elizabeth Kerstiens, Gilberto Garcia, Minhoo Kim

bioRxiv· February 2025

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Iron-associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice.
Max A Thorwald, Jose A Godoy-Lugo, Gilberto Garcia, Justine Silva, Minhoo Kim

Alzheimers Dement· January 2025

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Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging.
Naibedya Dutta, Joe A Gerke, Sofia F Odron, Joseph D Morris, Adam Hruby, Max A Thorwald

Geroscience· December 2024

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Transcript errors generate amyloid-like proteins in huwman cells.
Claire S Chung, Yi Kou, Sarah J Shemtov, Bert M Verheijen, Ilse Flores, Max A Thorwald

Nat Commun· October 2024

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Air pollution amyloidogenesis is attenuated by the gamma-secretase modulator GSM-15606.
Jose A Godoy-Lugo, Max A Thorwald, Mafalda Cacciottolo, Carla D'Agostino, Ararat Chakhoyan

Alzheimers Dement· September 2024

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Iron chelation by oral deferoxamine treatment decreased brain iron and iron signaling proteins.
Max A Thorwald, Jose A Godoy-Lugo, Naomi Santa Maria, Ararat Chakhoyan, Peggy O'Day

bioRxiv· August 2024

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Inhaled Pollutants of the Gero-Exposome and Later-Life Health.
Caleb E Finch, Max A Thorwald

J Gerontol A Biol Sci Med Sci· July 2024

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Iron associated lipid peroxidation in Alzheimers disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice.
Max Thorwald, Jose A Godoy-Lugo, Gilberto Garcia, Justine Silva, Minhoo Kim

bioRxiv· June 2024

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Microglial TLR4 Mediates White Matter Injury in a Combined Model of Diesel Exhaust Exposure and Cerebral Hypoperfusion.
Kristina Shkirkova, Alexandra N Demetriou, Saman Sizdahkhani, Krista Lamorie-Foote, Hongqiao Zhang, Max A Thorwald

Stroke· April 2024

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Protection against -associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice.
Cassandra J McGill, Amy Christensen, Wenjie Qian, Max A Thorwald, Jose Godoy Lugo

bioRxiv· March 2024

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Investigating impacts of marine sponge derived mycothiazole and its acetylated derivative on mitochondrial function and aging.
Naibedya Dutta, Joe A Gerke, Sofia F Odron, Joseph D Morris, Adam Hruby, Max A Thorwald

bioRxiv· November 2023

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Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity.
Hongqiao Zhang, Carla D'Agostino, Christopher Tulisiak, Max A Thorwald, Liza Bergkvist

Heliyon· April 2023

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