Publications by authors named "Maxence Nachury"

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BBSome-Mediated Clearance of Ubiquitinated IMPG2 Defines a Constitutive Ciliary Retrieval Pathway in Photoreceptors.
Tirthasree Das, Gary A Bradshaw, Jeanette Hyer, Markus Masek, Yien-Ming Kuo, Maxence V Nachury

bioRxiv· August 2025

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Intraflagellar transport trains can switch rails and move along multiple microtubules in intact primary cilia.
Shufeng Sun, Biqing Liang, Adam Koplas, Irina Tikhonenko, Maxence Nachury

Proc Natl Acad Sci U S A· April 2025

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Tonic ubiquitination of the central body weight regulator melanocortin receptor 4 (MC4R) promotes its constitutive exit from cilia.
Irene Ojeda-Naharros, Tirthasree Das, Ralph A Castro, J Fernando Bazan, Christian Vaisse, Maxence V Nachury

PLoS Biol· February 2025

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Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling.
Kimberly K Hoi, Wenlong Xia, Ming Ming Wei, Maria Jose Ulloa Navas, Jose-Manuel Garcia Verdugo, Maxence V Nachury

Cell Rep· October 2023

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The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia.
Swapnil Rohidas Shinde, David U Mick, Erika Aoki, Rachel B Rodrigues, Steven P Gygi, Maxence V Nachury

Dev Cell· April 2023

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MRAP2 regulates energy homeostasis by promoting primary cilia localization of MC4R.
Adelaide Bernard, Irene Ojeda Naharros, Xinyu Yue, Francois Mifsud, Abbey Blake, Maxence V Nachury

JCI Insight· January 2023

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The gymnastics of intraflagellar transport complexes keeps trains running inside cilia.
Maxence V Nachury

Cell· December 2022

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Shedding of ciliary vesicles at a glance.
Irene Ojeda Naharros, Maxence V Nachury

J Cell Sci· October 2022

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Time-resolved proteomics profiling of the ciliary Hedgehog response.
Elena A May, Marian Kalocsay, Inès Galtier D'Auriac, Patrick S Schuster, Steven P Gygi, Maxence V Nachury

J Cell Biol· May 2021

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Ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia.
Swapnil Rohidas Shinde, Andrew R Nager, Maxence V Nachury

J Cell Biol· December 2020

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Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes.
Shuang Yang, Kriti Bahl, Hui-Ting Chou, Jonathan Woodsmith, Ulrich Stelzl, Maxence V Nachury

Elife· June 2020

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The Molecular Architecture of Native BBSome Obtained by an Integrated Structural Approach.
Hui-Ting Chou, Luise Apelt, Daniel P Farrell, Susan Roehl White, Jonathan Woodsmith, Maxence V Nachury

Structure· September 2019

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Establishing and regulating the composition of cilia for signal transduction.
Maxence V Nachury, David U Mick

Nat Rev Mol Cell Biol· July 2019

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Effects of α-tubulin acetylation on microtubule structure and stability.
Lisa Eshun-Wilson, Rui Zhang, Didier Portran, Maxence V Nachury, Daniel B Toso

Proc Natl Acad Sci U S A· May 2019

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BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone.
Fan Ye, Andrew R Nager, Maxence V Nachury

J Cell Biol· May 2018

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The molecular machines that traffic signaling receptors into and out of cilia.
Maxence V Nachury

Curr Opin Cell Biol· April 2018

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A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.
David K Breslow, Sascha Hoogendoorn, Adam R Kopp, David W Morgens, Brandon K Vu, Maxence V Nachury

Nat Genet· March 2018

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BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8.
Shinsuke Niwa, Li Tao, Sharon Y Lu, Gerald M Liew, Wei Feng, Maxence V Nachury

Curr Biol· September 2017

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Fifteen years of research on oral-facial-digital syndromes: from 1 to 16 causal genes.
Ange-Line Bruel, Brunella Franco, Yannis Duffourd, Julien Thevenon, Laurence Jego, Maxence V Nachury

J Med Genet· June 2017

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Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action.
Jonathan B Steinman, Cristina C Santarossa, Rand M Miller, Lola S Yu, Anna S Serpinskaya, Maxence V Nachury

Elife· May 2017

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Tubulin acetylation protects long-lived microtubules against mechanical ageing.
Didier Portran, Laura Schaedel, Zhenjie Xu, Manuel Théry, Maxence V Nachury

Nat Cell Biol· April 2017

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Microtubules acquire resistance from mechanical breakage through intralumenal acetylation.
Zhenjie Xu, Laura Schaedel, Didier Portran, Andrea Aguilar, Jérémie Gaillard, Maxence V Nachury

Science· April 2017

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Membrane traffic control by cytoskeletal and molecular machines.
Tina H Lee, Maxence V Nachury

Mol Biol Cell· March 2017

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An Actin Network Dispatches Ciliary GPCRs into Extracellular Vesicles to Modulate Signaling.
Andrew R Nager, Jaclyn S Goldstein, Vicente Herranz-Pérez, Didier Portran, Fan Ye, Maxence V Nachury

Cell· January 2017

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Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei.
Gerasimos Langousis, Michelle M Shimogawa, Edwin A Saada, Ajay A Vashisht, Roberto Spreafico, Maxence V Nachury

Proc Natl Acad Sci U S A· January 2016

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