Publications by authors named "Maxim Puchkov"

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Drug loading mechanism of hollow hydroxyapatite microcapsules.
Jonas Kost, Nathalie Peyer, Jörg Huwyler, Maxim Puchkov

Eur J Pharm Biopharm· September 2025

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Effects of Subanesthetic Oromucosal Dexmedetomidine on Sleep in Humans: A Randomized, Controlled Pharmacokinetics-Pharmacodynamics Study.
Laura K Schnider, Marta Ratajczak, Rafael Wespi, Jacqueline G Kientsch, Francesco Bavato, Maxim Puchkov

Anesthesiology· March 2025

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Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: Α factorial dose-escalation study.
Klemens Egger, Javier Jareño Redondo, Jovin Müller, Joëlle Dornbierer, John Smallridge, Maxim Puchkov

Biomed Pharmacother· March 2025

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Pharmacokinetics and pharmacodynamics of an innovative psychedelic N,N-dimethyltryptamine/harmine formulation in healthy participants: a randomized controlled trial.
Michael J Mueller, Helena D Aicher, Dario A Dornbierer, Laurenz Marten, Dila Suay, Maxim Puchkov

Int J Neuropsychopharmacol· December 2024

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Advanced analysis of disintegrating pharmaceutical compacts using deep learning-based segmentation of time-resolved micro-tomography images.
Samuel Waldner, Erwin Wendelspiess, Pascal Detampel, Christian M Schlepütz, Jörg Huwyler, Maxim Puchkov

Heliyon· February 2024

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Overcoming the clinical challenges of traditional ayahuasca: a first-in-human trial exploring novel routes of administration of N,N-Dimethyltryptamine and harmine.
Dario A Dornbierer, Laurenz Marten, Jovin Mueller, Helena D Aicher, Michael J Mueller, Maxim Puchkov

Front Pharmacol· November 2023

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The processes behind drug loading and release in porous drug delivery systems.
Maryam Farzan, Roger Roth, Joachim Schoelkopf, Jörg Huwyler, Maxim Puchkov

Eur J Pharm Biopharm· August 2023

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Colonic delivery of metronidazole-loaded capsules for local treatment of bacterial infections: A clinical pharmacoscintigraphy study.
Daniel Preisig, Felipe Varum, Roberto Bravo, Claudia Hartig, Johannes Spleiss, Maxim Puchkov

Eur J Pharm Biopharm· August 2021

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Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2.
Fabio Bachmann, Urs Duthaler, Henriette E Meyer Zu Schwabedissen, Maxim Puchkov, Jörg Huwyler

Clin Pharmacol Ther· June 2021

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Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans.
Andreas Schittny, Samuel Waldner, Urs Duthaler, Alexander Vorobyev, Rimma Abramovich, Maxim Puchkov

Pharmaceutics· March 2021

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High Acceptability of an Orally Dispersible Tablet Formulation by Children.
Leonie Wagner-Hattler, Klara Kiene, Julia Bielicki, Marc Pfister, Maxim Puchkov

Children (Basel)· March 2021

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Mechanisms of increased bioavailability through amorphous solid dispersions: a review.
Andreas Schittny, Jörg Huwyler, Maxim Puchkov

Drug Deliv· December 2020

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[Abuse deterrent drug formulations for opioids].
Madlaina Matter, Stefan Mühlebach, Maxim Puchkov, Jörg Huwyler

Ther Umsch· September 2020

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Shedding Light on Metal-Based Nanoparticles in Zebrafish by Computed Tomography with Micrometer Resolution.
Emre Cörek, Griffin Rodgers, Stefan Siegrist, Tomaz Einfalt, Pascal Detampel, Maxim Puchkov

Small· August 2020

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Spontaneous In Situ Formation of Liposomes from Inert Porous Microparticles for Oral Drug Delivery.
Maryam Farzan, Gabriela Québatte, Katrin Strittmatter, Florentine Marianne Hilty, Joachim Schoelkopf, Maxim Puchkov

Pharmaceutics· August 2020

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Impact of Insoluble Separation Layer Mechanical Properties on Disintegration and Dissolution Kinetics of Multilayer Tablets.
Reiji Yokoyama, Go Kimura, Jörg Huwyler, Ken-Ichi Hosoya, Maxim Puchkov

Pharmaceutics· May 2020

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Efficacy and Safety of Ascending Dosages of Moxidectin and Moxidectin-albendazole Against Trichuris trichiura in Adolescents: A Randomized Controlled Trial.
Ladina Keller, Marta S Palmeirim, Shaali M Ame, Said M Ali, Maxim Puchkov

Clin Infect Dis· March 2020

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Pharmacokinetics and phenotyping properties of the Basel phenotyping cocktail combination capsule in healthy male adults.
Claudia Suenderhauf, Benjamin Berger, Maxim Puchkov, Yasmin Schmid, Sabine Müller

Br J Clin Pharmacol· February 2020

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Study of drug particle distributions within mini-tablets using synchrotron X-ray microtomography and superpixel image clustering.
Leonie Wagner-Hattler, Gabriela Québatte, Jennifer Keiser, Joachim Schoelkopf, Christian M Schlepütz, Maxim Puchkov

Int J Pharm· January 2020

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Stability investigation of FCC-based tablets for oral suspension with caffeine and oxantel pamoate as model drugs.
Leonie Wagner-Hattler, Joachim Schoelkopf, Jörg Huwyler, Maxim Puchkov

Drug Dev Ind Pharm· February 2019

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Loading of Porous Functionalized Calcium Carbonate Microparticles: Distribution Analysis with Focused Ion Beam Electron Microscopy and Mercury Porosimetry.
Maryam Farzan, Roger Roth, Gabriela Québatte, Joachim Schoelkopf, Jörg Huwyler, Maxim Puchkov

Pharmaceutics· January 2019

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Modeling of Disintegration and Dissolution Behavior of Mefenamic Acid Formulation Using Numeric Solution of Noyes-Whitney Equation with Cellular Automata on Microtomographic and Algorithmically Generated Surfaces.
Reiji Yokoyama, Go Kimura, Christian M Schlepütz, Jörg Huwyler, Maxim Puchkov

Pharmaceutics· December 2018

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Efficacy and tolerability of moxidectin alone and in co-administration with albendazole and tribendimidine versus albendazole plus oxantel pamoate against Trichuris trichiura infections: a randomised, non-inferiority, single-blind trial.
Beatrice Barda, Shaali M Ame, Said M Ali, Marco Albonico, Maxim Puchkov

Lancet Infect Dis· August 2018

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Efficacy and tolerability of triple drug therapy with albendazole, pyrantel pamoate, and oxantel pamoate compared with albendazole plus oxantel pamoate, pyrantel pamoate plus oxantel pamoate, and mebendazole plus pyrantel pamoate and oxantel pamoate against hookworm infections in school-aged children in Laos: a randomised, single-blind trial.
Wendelin Moser, Somphou Sayasone, Syda Xayavong, Bangon Bounheuang, Maxim Puchkov

Lancet Infect Dis· July 2018

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In vitro characterization and mouthfeel study of functionalized calcium carbonate in orally disintegrating tablets.
Leonie Wagner-Hattler, Katharina Wyss, Joachim Schoelkopf, Jörg Huwyler, Maxim Puchkov

Int J Pharm· December 2017

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