Publications by authors named "Maxwell Sehested"

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Imaging of treatment response to the combination of carboplatin and paclitaxel in human ovarian cancer xenograft tumors in mice using FDG and FLT PET.
Mette Munk Jensen, Kamille Dumong Erichsen, Fredrik Björkling, Jacob Madsen, Peter Buhl Jensen, Maxwell Sehested

PLoS One· February 2015

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Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship.
Mette K Christensen, Kamille D Erichsen, Uffe H Olesen, Jette Tjørnelund, Peter Fristrup, Maxwell Sehested

J Med Chem· November 2013

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[18F]FLT and [18F]FDG PET for non-invasive treatment monitoring of the nicotinamide phosphoribosyltransferase inhibitor APO866 in human xenografts.
Mette Munk Jensen, Kamille Dumong Erichsen, Camilla Bardram Johnbeck, Fredrik Björkling, Jacob Madsen, Maxwell Sehested

PLoS One· July 2013

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[18F]FLT PET for non-invasive assessment of tumor sensitivity to chemotherapy: studies with experimental chemotherapy TP202377 in human cancer xenografts in mice.
Mette Munk Jensen, Kamille Dumong Erichsen, Fredrik Björkling, Jacob Madsen, Peter Buhl Jensen, Maxwell Sehested

PLoS One· May 2013

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[18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice.
Mette Munk Jensen, Kamille Dumong Erichsen, Camilla Bardram Johnbeck, Fredrik Björkling, Jacob Madsen, Maxwell Sehested

BMC Cancer· April 2013

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Treatment of experimental extravasation of amrubicin, liposomal doxorubicin, and mitoxantrone with dexrazoxane.
Seppo W Langer, Annemette V Thougaard, Maxwell Sehested, Peter Buhl Jensen

Cancer Chemother Pharmacol· February 2012

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Novel small molecule drugs inhibit tumor cell metabolism and show potent anti-tumorigenic potential.
Christina Trojel-Hansen, Kamille Dumong Erichsen, Mette Knak Christensen, Peter Buhl Jensen, Maxwell Sehested

Cancer Chemother Pharmacol· July 2011

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Expression patterns of nicotinamide phosphoribosyltransferase and nicotinic acid phosphoribosyltransferase in human malignant lymphomas.
Uffe Høgh Olesen, Nina Hastrup, Maxwell Sehested

APMIS· April 2011

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Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.
Uffe H Olesen, Jakob G Petersen, Antje Garten, Wieland Kiess, Jun Yoshino, Maxwell Sehested

BMC Cancer· December 2010

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Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones.
Mette K Christensen, Kamille D Erichsen, Christina Trojel-Hansen, Jette Tjørnelund, Søren J Nielsen, Maxwell Sehested

J Med Chem· October 2010

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Early detection of response to experimental chemotherapeutic Top216 with [18F]FLT and [18F]FDG PET in human ovary cancer xenografts in mice.
Mette Munk Jensen, Kamille Dumong Erichsen, Fredrik Björkling, Jacob Madsen, Peter Buhl Jensen, Maxwell Sehested

PLoS One· September 2010

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Proteomic profiling of human colon cancer cells treated with the histone deacetylase inhibitor belinostat.
Hans Christian Beck, Jørgen Petersen, Søren Jensby Nielsen, Christian Morsczeck, Peter B Jensen, Maxwell Sehested

Electrophoresis· August 2010

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A preclinical study on the rescue of normal tissue by nicotinic acid in high-dose treatment with APO866, a specific nicotinamide phosphoribosyltransferase inhibitor.
Uffe Høgh Olesen, Annemette V Thougaard, Peter Buhl Jensen, Maxwell Sehested

Mol Cancer Ther· June 2010

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Ossifying thymoma associated with refractory myasthenia gravis.
Eric Santoni-Rugiu, Jesper Ravn, Maxwell Sehested, Klaus Hansen, Claus B Andersen

APMIS· April 2010

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A murine experimental anthracycline extravasation model: pathology and study of the involvement of topoisomerase II alpha and iron in the mechanism of tissue damage.
Annemette V Thougaard, Seppo W Langer, Bo Hainau, Morten Grauslund, Birgitte Ravn Juhl, Maxwell Sehested

Toxicology· February 2010

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Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts.
Anne Monks, Curtis D Hose, Patrick Pezzoli, Sudhir Kondapaka, Gordon Vansant, Maxwell Sehested

Anticancer Drugs· September 2009

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Anthracycline extravasation: a comprehensive review of experimental and clinical treatments.
Seppo W Langer, Maxwell Sehested, Peter Buhl Jensen

Tumori· September 2009

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Histone deacetylase 1, 2, 6 and acetylated histone H4 in B- and T-cell lymphomas.
Lena Marquard, Christian B Poulsen, Lise Mette Gjerdrum, Peter de Nully Brown, Ib J Christensen, Maxwell Sehested

Histopathology· May 2009

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Novel amide derivatives as inhibitors of histone deacetylase: design, synthesis and SAR.
Victor Andrianov, Vija Gailite, Daina Lola, Einars Loza, Valentina Semenikhina, Maxwell Sehested

Eur J Med Chem· March 2009

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Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy.
Elke Martin, Annemette Vinding Thougaard, Morten Grauslund, Peter B Jensen, Fredrik Bjorkling, Maxwell Sehested

Toxicology· January 2009

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Photocarcinogenesis of topical tazarotene and isotretinoin alone and in combination with valproic acid in hairless mice.
Catharina M Lerche, Peter A Philipsen, Maxwell Sehested, Hans Christian Wulf

Exp Dermatol· November 2008

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Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells.
Marielle Dejligbjerg, Morten Grauslund, Thomas Litman, Laura Collins, Xiaozhong Qian, Maxwell Sehested

Mol Cancer· September 2008

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Identification of predictive biomarkers for the histone deacetylase inhibitor belinostat in a panel of human cancer cell lines.
Marielle Dejligbjerg, Morten Grauslund, Ib Jarle Christensen, Jette Tjørnelund, Peter Buhl Jensen, Maxwell Sehested

Cancer Biomark· August 2008

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Monitoring the effect of belinostat in solid tumors by H4 acetylation.
Lena Marquard, Kamille Dumong Petersen, Morten Persson, Kirsten Damgaard Hoff, Peter Buhl Jensen, Maxwell Sehested

APMIS· May 2008

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