Publications by authors named "Mebratu A Bitew"

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A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during Toxoplasma gondii adaptation to lipid-rich conditions.
Mebratu A Bitew, Tatiana C Paredes-Santos, Parag Maru, Shruthi Krishnamurthy, Yifan Wang

Nat Commun· December 2025

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A genome-wide CRISPR screen identifies GRA38 as a key regulator of lipid homeostasis during adaptation to lipid-rich conditions.
Mebratu A Bitew, Tatiana C Paredes-Santos, Parag Maru, Shruthi Krishnamurthy, Yifan Wang

Res Sq· April 2025

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Characterisation of putative lactate synthetic pathways of Coxiella burnetii.
Janine Hofmann, Mebratu A Bitew, Miku Kuba, David P De Souza, Hayley J Newton

PLoS One· July 2024

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Two putative pore-forming proteins, GRA47 and GRA72, influence small molecule permeability of the parasitophorous vacuole.
Mebratu A Bitew, Pablo S Gaete, Christopher Swale, Parag Maru, Jorge E Contreras

mBio· March 2024

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GRA47 and GRA72 are pore-forming proteins that influence small molecule permeability of the parasitophorous vacuole.
Mebratu A Bitew, Pablo S Gaete, Christopher Swale, Parag Maru, Jorge E Contreras

bioRxiv· November 2023

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Genome-wide CRISPR screen identifies genes synthetically lethal with GRA17, a nutrient channel encoding gene in Toxoplasma.
Tatiana C Paredes-Santos, Mebratu A Bitew, Christopher Swale, Felipe Rodriguez, Shruthi Krishnamurthy

PLoS Pathog· July 2023

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CRISPR Screens Identify Genes That Determine Parasite Fitness in Interferon Gamma-Stimulated Human Cells.
Shruthi Krishnamurthy, Parag Maru, Yifan Wang, Mebratu A Bitew, Debanjan Mukhopadhyay

mBio· April 2023

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SdrA, an NADP(H)-regenerating enzyme, is crucial for Coxiella burnetii to resist oxidative stress and replicate intracellularly.
Mebratu A Bitew, Janine Hofmann, David P De Souza, Nadeeka K Wawegama, Hayley J Newton

Cell Microbiol· May 2020

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Meso-tartrate inhibits intracellular replication of Coxiella burnetii, the causative agent of the zoonotic disease Q fever.
Mebratu A Bitew, Nadeeka K Wawegama, Hayley J Newton, Fiona M Sansom

Pathog Dis· November 2019

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NAD synthesis is required for intracellular replication of , the causative agent of the neglected zoonotic disease Q fever.
Mebratu A Bitew, Chen Ai Khoo, Nitika Neha, David P De Souza, Dedreia Tull

J Biol Chem· November 2018

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