Publications by authors named "Meg Perumal"

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Evaluation of 2-deoxy-2-[18F]fluoro-D-glucose- and 3'-deoxy-3'-[18F]fluorothymidine-positron emission tomography as biomarkers of therapy response in platinum-resistant ovarian cancer.
Meg Perumal, Euan A Stronach, Hani Gabra, Eric O Aboagye

Mol Imaging Biol· December 2012

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Radiosynthesis and in vivo tumor uptake of 2-deoxy-2-[(18)F]fluoro-myo-inositol.
Laurence Carroll, Meg Perumal, Neil Vasdev, Edward Robins, Eric O Aboagye

Bioorg Med Chem Lett· October 2012

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Targeting somatostatin receptors: preclinical evaluation of novel 18F-fluoroethyltriazole-Tyr3-octreotate analogs for PET.
Julius Leyton, Lisa Iddon, Meg Perumal, Bard Indrevoll, Matthias Glaser

J Nucl Med· September 2011

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Glucose metabolism measured by [¹⁸F]fluorodeoxyglucose positron emission tomography is independent of PTEN/AKT status in human colon carcinoma cells.
Quang-Dé Nguyen, Meg Perumal, Todd A Waldman, Eric O Aboagye

Transl Oncol· August 2011

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Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas.
Monika Golinska, Helen Troy, Yuen-Li Chung, Paul M McSheehy, Manuel Mayr, Meg Perumal

BMC Cancer· May 2011

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Radiosynthesis and pre-clinical evaluation of [(18)F]fluoro-[1,2-(2)H(4)]choline.
Graham Smith, Yongjun Zhao, Julius Leyton, Bo Shan, Quang-de Nguyen, Meg Perumal

Nucl Med Biol· January 2011

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[18F]fluoromethyl-[1,2-2H4]-choline: a novel radiotracer for imaging choline metabolism in tumors by positron emission tomography.
Julius Leyton, Graham Smith, Yongjun Zhao, Meg Perumal, Quang-De Nguyen

Cancer Res· October 2009

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Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide.
Quang-Dé Nguyen, Graham Smith, Matthias Glaser, Meg Perumal, Erik Arstad

Proc Natl Acad Sci U S A· September 2009

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Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide.
Graham Smith, Matthias Glaser, Meg Perumal, Quang-De Nguyen, Bo Shan

J Med Chem· December 2008

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Noninvasive imaging of cell proliferation following mitogenic extracellular kinase inhibition by PD0325901.
Julius Leyton, Graham Smith, Mark Lees, Meg Perumal, Quang-de Nguyen

Mol Cancer Ther· September 2008

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Imaging pharmacodynamics of the alpha-folate receptor-targeted thymidylate synthase inhibitor BGC 945.
Radhakrishna G Pillai, Martin Forster, Meg Perumal, Fraser Mitchell, Julius Leyton

Cancer Res· May 2008

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Mechanism of action of the Aurora kinase inhibitor CCT129202 and in vivo quantification of biological activity.
Florence Chan, Chongbo Sun, Meg Perumal, Quang-De Nguyen, Vassilios Bavetsias

Mol Cancer Ther· December 2007

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Redistribution of nucleoside transporters to the cell membrane provides a novel approach for imaging thymidylate synthase inhibition by positron emission tomography.
Meg Perumal, Radhakrishna G Pillai, Henryk Barthel, Julius Leyton, John R Latigo

Cancer Res· September 2006

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In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography.
Julius Leyton, John P Alao, Marco Da Costa, Alexandra V Stavropoulou, John R Latigo, Meg Perumal

Cancer Res· August 2006

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Early detection of tumor response to chemotherapy by 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography: the effect of cisplatin on a fibrosarcoma tumor model in vivo.
Julius Leyton, John R Latigo, Meg Perumal, Harmandeep Dhaliwal, Qimin He

Cancer Res· May 2005

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The uptake of 3'-deoxy-3'-[18F]fluorothymidine into L5178Y tumours in vivo is dependent on thymidine kinase 1 protein levels.
Henryk Barthel, Meg Perumal, John Latigo, Qimin He, Frank Brady

Eur J Nucl Med Mol Imaging· March 2005

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