Publications by authors named "Megan Lancaster"

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Mapping the Functional Landscape of KCNQ1 to Define Ion Channel Mechanisms and Arrhythmia Risk.
M Lorena Harvey, Ellen M Osborn, Megan C Lancaster, Jeremy E Smith, Qianyi Shen

medRxiv· December 2025

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Genetic evaluation of early-onset atrial fibrillation: impact on patient management.
J Lukas Laws, Mahsima Shabani, Hollie L Williams, Dakota D Grauherr, Wendy M Kilbourne, Megan Lancaster

Eur Heart J· October 2025

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The functional landscape of coding variation in the familial hypercholesterolemia gene .
Daniel R Tabet, Atina G Coté, Megan C Lancaster, Jochen Weile, Ashyad Rayhan

Science· October 2025

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Creating an atlas of variant effects to resolve variants of uncertain significance and guide cardiovascular medicine.
Andrew M Glazer, Daniel R Tabet, Victoria N Parikh, Brett M Kroncke, Atina G Cote, Megan C Lancaster

Nat Rev Cardiol· September 2025

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The Therapeutic Impact of Genetic Evaluation in an Atrial Fibrillation Precision Medicine Clinic.
J Lukas Laws, Mahsima Shabani, Hollie L Williams, Dakota D Grauherr, Wendy M Kilbourne, Megan Lancaster

medRxiv· March 2025

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Multiplexed Assays of Variant Effect and Automated Patch Clamping Improve -LQTS Variant Classification and Cardiac Event Risk Stratification.
Matthew J O'Neill, Chai-Ann Ng, Takanori Aizawa, Luca Sala, Sahej Bains, Megan C Lancaster

Circulation· December 2024

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A Polygenic Predictor of Baseline QTc is Associated With Sotalol-Induced QT Prolongation.
Megan C Lancaster, Giovanni Davogustto, Edi Prifti, Claire Perret, Christian Funck-Brentano

Circulation· December 2024

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Clinical Characteristics and Outcomes in Patients With Atrial Fibrillation and Pathogenic TTN Variants.
Zain M Virk, Majd A El-Harasis, Zachary T Yoneda, Katherine C Anderson, Lili Sun, Megan C Lancaster

JACC Clin Electrophysiol· November 2024

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Detection of distant relatedness in biobanks to identify undiagnosed cases of Mendelian disease as applied to Long QT syndrome.
Megan C Lancaster, Hung-Hsin Chen, M Benjamin Shoemaker, Matthew R Fleming, Teresa L Strickland

Nat Commun· August 2024

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Benchmarking computational variant effect predictors by their ability to infer human traits.
Daniel R Tabet, Da Kuang, Megan C Lancaster, Roujia Li, Karen Liu

Genome Biol· July 2024

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Multiplexed Assays of Variant Effect and Automated Patch-clamping Improve -LQTS Variant Classification and Cardiac Event Risk Stratification.
Matthew J O'Neill, Chai-Ann Ng, Takanori Aizawa, Luca Sala, Sahej Bains, Megan Lancaster

medRxiv· June 2024

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Multifocal Ectopic Purkinje Premature Contractions due to neutralization of an negative charge: structural insights into the gating pore hypothesis.
Andrew M Glazer, Tao Yang, Bian Li, Dana Page, Mohamed Fouda, Megan C Lancaster

bioRxiv· February 2024

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Detection of distant relatedness in biobanks for identification of undiagnosed carriers of a Mendelian disease variant: application to Long QT Syndrome.
Megan C Lancaster, Hung-Hsin Chen, M Benjamin Shoemaker, Matthew R Fleming, James T Baker

Res Sq· September 2023

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Detection of distant familial relatedness in biobanks for identification of undiagnosed carriers of a Mendelian disease variant: application to Long QT syndrome.
Megan C Lancaster, Hung-Hsin Chen, M Benjamin Shoemaker, Matthew R Fleming, James T Baker

medRxiv· April 2023

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Left atrial appendage dimension predicts elevated brain natriuretic peptide in nonvalvular atrial fibrillation.
Jason A Cook, Megan C Lancaster, Arvindh N Kanagasundram, Heather L Prigmore, Kim L Sandler

J Cardiovasc Electrophysiol· January 2023

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Effectiveness of Intense Accent Modification Training With Refugees From Burma.
Angela Burda, Lindsey Squires, David Krupke, Andrew Arthur, Mariana Bahia, Megan Lancaster

Am J Speech Lang Pathol· November 2022

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Arrhythmias as Presentation of Genetic Cardiomyopathy.
J Lukas Laws, Megan C Lancaster, M Ben Shoemaker, William G Stevenson, Rebecca R Hung

Circ Res· May 2022

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A challenging VT ablation with a large cardiac tumor.
Carlos Lynes, Megan Lancaster, Asad A Aboud, William Stevenson, Kelly Schlendorf

J Cardiovasc Electrophysiol· September 2021

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The Author Reply.
Alaa Mabrouk Salem Omar, Megan Cummins Lancaster, Sukrit Narula, Hemant Kulkarni, Jagat Narula

JACC Cardiovasc Imaging· January 2020

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Phenotypic Clustering of Left Ventricular Diastolic Function Parameters: Patterns and Prognostic Relevance.
Megan Cummins Lancaster, Alaa Mabrouk Salem Omar, Sukrit Narula, Hemant Kulkarni, Jagat Narula

JACC Cardiovasc Imaging· July 2019

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