Publications by authors named "Megan Leander"

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High-throughput discovery of transmembrane helix dimers from human single-pass membrane proteins with TOXGREEN sort-seq.
Samantha M Anderson, Joshua Choi, Emma M Cushman, Megan Leander, Srivatsan Raman

PNAS Nexus· October 2025

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High-throughput discovery of transmembrane helix dimers from human single-pass membrane proteins with TOXGREEN sort-seq.
Samantha M Anderson, Joshua Choi, Emma M Cushman, Megan Leander, Srivatsan Raman

bioRxiv· May 2025

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Deep mutational scanning and machine learning reveal structural and molecular rules governing allosteric hotspots in homologous proteins.
Megan Leander, Zhuang Liu, Qiang Cui, Srivatsan Raman

Elife· October 2022

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Mapping the functional landscape of the receptor binding domain of T7 bacteriophage by deep mutational scanning.
Phil Huss, Anthony Meger, Megan Leander, Kyle Nishikawa, Srivatsan Raman

Elife· March 2021

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Functional plasticity and evolutionary adaptation of allosteric regulation.
Megan Leander, Yuchen Yuan, Anthony Meger, Qiang Cui, Srivatsan Raman

Proc Natl Acad Sci U S A· October 2020

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Cardiac contractility structure-activity relationship and ligand-receptor interactions; the discovery of unique and novel molecular switches in myosuppressin signaling.
Megan Leander, Chloe Bass, Kathryn Marchetti, Benjamin F Maynard, Juan Pedro Wulff

PLoS One· February 2016

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Structure-activity relationships of FMRF-NH2 peptides demonstrate A role for the conserved C terminus and unique N-terminal extension in modulating cardiac contractility.
Benjamin F Maynard, Chloe Bass, Chris Katanski, Kiran Thakur, Beth Manoogian, Megan Leander

PLoS One· June 2014

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