Publications by authors named "Megan Steain"

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De novo cyclic peptides allow visualisation of the monomeric and functional amyloid conformations of the kinase RIPK3.
Jessica A Buchanan, Olivia Lavidis, Nicholas Shields, Katriona Harrison, Huy T Nguyen, Megan Steain

Biochem J· January 2026

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An RGD motif on SARS-CoV-2 Spike induces TGF-β signaling and downregulates interferon.
Nicholas P Gracie, Anupriya Aggarwal, Rachel Luo, Mitchell Spicer, Sobia Idrees, Megan C Steain

J Virol· September 2025

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Upper respiratory tract immunization with PamCys-adjuvanted spike protein vaccine achieves sterilizing protection against SARS-CoV-2.
Erica L Stewart, Skye Stockdale, Matt D Johansen, Lachlan Smith, Sibel Alca, Megan Steain

Front Immunol· September 2025

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An adjuvanted chimeric spike antigen boosts lung-resident memory T-cells and induces pan-sarbecovirus protective immunity.
Claudio Counoupas, Elizabeth Chan, Paco Pino, Joshua Armitano, Matt D Johansen, Megan Steain

NPJ Vaccines· May 2025

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An LNP-mRNA vaccine modulates innate cell trafficking and promotes polyfunctional Th1 CD4 T cell responses to enhance BCG-induced protective immunity against Mycobacterium tuberculosis.
Hannah Lukeman, Hareth Al-Wassiti, Stewart A Fabb, Leonard Lim, Trixie Wang, Megan Steain

EBioMedicine· March 2025

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Optimisation of a multiplexed, high throughput assay to measure neutralising antibodies against SARS-CoV-2 variants.
Caroline L Ashley, Malik Bloul, Sibel Alca, Lachlan Smith, Wang Jin, Megan Steain

J Virol Methods· February 2025

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The Batalogue: an overview of betacoronaviruses with future pandemic potential.
Sarah Baird, Edward C Holmes, Caroline L Ashley, James A Triccas, Megan Steain

FEMS Microbiol Rev· January 2025

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Intranasal Self-Adjuvanted Lipopeptide Vaccines Elicit High Antibody Titers and Strong Cellular Responses against SARS-CoV-2.
Joshua W C Maxwell, Skye Stockdale, Erica L Stewart, Caroline L Ashley, Lachlan J Smith, Megan Steain

ACS Infect Dis· September 2024

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Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN) is a cellular receptor for delta inulin adjuvant.
Erica L Stewart, Claudio Counoupas, Megan Steain, Caroline Ashley, Sibel Alca

Immunol Cell Biol· August 2024

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Corrigendum: Late-stage MC38 tumours recapitulate features of human colorectal cancer - implications for appropriate timepoint selection in preclinical studies.
Nicholas J Shields, Estelle M Peyroux, Angela L Ferguson, Megan Steain, Silke Neumann

Front Immunol· June 2024

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A unique cytotoxic CD4 T cell-signature defines critical COVID-19.
Sarah Baird, Caroline L Ashley, Felix Marsh-Wakefield, Sibel Alca, Thomas M Ashhurst, Megan Steain

Clin Transl Immunology· August 2023

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Late-stage MC38 tumours recapitulate features of human colorectal cancer - implications for appropriate timepoint selection in preclinical studies.
Nicholas J Shields, Estelle M Peyroux, Angela L Ferguson, Megan Steain, Silke Neumann

Front Immunol· May 2023

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Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis.
Deborah Cromer, Megan Steain, Arnold Reynaldi, Timothy E Schlub, Shanchita R Khan

Nat Commun· March 2023

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Varicella Zoster Virus Impairs Expression of the Nonclassical Major Histocompatibility Complex Class I-Related Gene Protein (MR1).
Shivam K Purohit, Carolyn Samer, Hamish E G McWilliam, Renee Traves, Megan Steain

J Infect Dis· February 2023

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Correlates of Protection, Thresholds of Protection, and Immunobridging among Persons with SARS-CoV-2 Infection.
David S Khoury, Timothy E Schlub, Deborah Cromer, Megan Steain, Youyi Fong

Emerg Infect Dis· February 2023

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Modulation of Apoptosis and Cell Death Pathways by Varicella-Zoster Virus.
Megan Steain, Barry Slobedman, Allison Abendroth

Curr Top Microbiol Immunol· November 2022

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Mucosal TLR2-activating protein-based vaccination induces potent pulmonary immunity and protection against SARS-CoV-2 in mice.
Anneliese S Ashhurst, Matt D Johansen, Joshua W C Maxwell, Skye Stockdale, Caroline L Ashley, Megan Steain

Nat Commun· November 2022

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Relating In Vitro Neutralization Level and Protection in the CVnCoV (CUREVAC) Trial.
Deborah Cromer, Arnold Reynaldi, Megan Steain, James A Triccas, Miles P Davenport

Clin Infect Dis· August 2022

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Assessing the suitability of long non-coding RNAs as therapeutic targets and biomarkers in SARS-CoV-2 infection.
Yichen Zhong, Caroline L Ashley, Megan Steain, Sandro Fernandes Ataide

Front Mol Biosci· August 2022

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Mucosal immunization with a delta-inulin adjuvanted recombinant spike vaccine elicits lung-resident immune memory and protects mice against SARS-CoV-2.
Erica L Stewart, Claudio Counoupas, Matt D Johansen, Duc H Nguyen, Stefan Miemczyk, Megan Steain

Mucosal Immunol· June 2022

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The RHIM of the Immune Adaptor Protein TRIF Forms Hybrid Amyloids with Other Necroptosis-Associated Proteins.
Max O D G Baker, Nirukshan Shanmugam, Chi L L Pham, Sarah R Ball, Emma Sierecki, Megan Steain

Molecules· May 2022

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High-Titer Neutralizing Antibodies against the SARS-CoV-2 Delta Variant Induced by Alhydroxyquim-II-Adjuvanted Trimeric Spike Antigens.
Claudio Counoupas, Paco Pino, Alberto O Stella, Caroline Ashley, Hannah Lukeman, Megan Steain

Microbiol Spectr· February 2022

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Neutralising antibody titres as predictors of protection against SARS-CoV-2 variants and the impact of boosting: a meta-analysis.
Deborah Cromer, Megan Steain, Arnold Reynaldi, Timothy E Schlub, Adam K Wheatley

Lancet Microbe· January 2022

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A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection.
Claudio Counoupas, Matt D Johansen, Alberto O Stella, Duc H Nguyen, Angela L Ferguson, Megan C Steain

NPJ Vaccines· November 2021

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Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display.
Alexander Norman, Charlotte Franck, Mary Christie, Paige M E Hawkins, Karishma Patel, Megan Steain

ACS Cent Sci· June 2021

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