Publications by authors named "Meghan Flaherty"

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An ANGPTL4 inhibitory antibody safely improves lipid profiles in non-human primates.
Beryl B Cummings, Page R Bouchard, Mark N Milton, Peter F Moesta, Vyas Ramanan, Meghan M Flaherty

EBioMedicine· July 2025

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Safety and efficacy of a novel ANGPTL4 inhibitory antibody for lipid lowering: results from phase 1 and phase 1b/2a clinical studies.
Beryl B Cummings, Mark P Joing, Page R Bouchard, Mark N Milton, Peter F Moesta, Meghan M Flaherty

Lancet· May 2025

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Erratum to: An Afucosylated Anti-CD32b Monoclonal Antibody Induced Platelet-Mediated Adverse Events in a Human Fcγ Receptor Transgenic Mouse Model and Its Potential Human Translatability.
Babette Wolf, Valentina Jeliazkova-Mecheva, Alberto Del Rio-Espinola, Julie Boisclair, Dana Walker, Meghan Flaherty

Toxicol Sci· January 2022

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An Afucosylated Anti-CD32b Monoclonal Antibody Induced Platelet-Mediated Adverse Events in a Human Fcγ Receptor Transgenic Mouse Model and Its Potential Human Translatability.
Babette Wolf, Valentina Jeliazkova-Mecheva, Alberto Del Rio-Espinola, Julie Boisclair, Dana Walker, Meghan Flaherty

Toxicol Sci· December 2021

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Development of Anti-CD32b Antibodies with Enhanced Fc Function for the Treatment of B and Plasma Cell Malignancies.
Haihui Lu, Ryan D Molony, Dongshu Chen, Sunyoung Jang, Babette Wolf, Meghan Flaherty

Mol Cancer Ther· October 2020

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Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation.
Helen Prior, Paul Baldrick, Sonja Beken, Helen Booler, Nancy Bower, Meghan Flaherty

Regul Toxicol Pharmacol· June 2020

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Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers.
Carl U Bialucha, Scott D Collins, Xiao Li, Parmita Saxena, Xiamei Zhang, Meghan M Flaherty

Cancer Discov· September 2017

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23814, an Inhibitory Antibody of Ligand-Mediated Notch1 Activation, Modulates Angiogenesis and Inhibits Tumor Growth without Gastrointestinal Toxicity.
Theresa Proia, Feng Jiang, Alisa Bell, Richard Nicoletti, Lingxin Kong, Meghan Flaherty

Mol Cancer Ther· August 2015

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Nonclinical evaluation of GMA161--an antihuman CD16 (FcγRIII) monoclonal antibody for treatment of autoimmune disorders in CD16 transgenic mice.
Meghan M Flaherty, Timothy K MacLachlan, Misty Troutt, Tomas Magee, Nadine Tuaillon

Toxicol Sci· January 2012

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Alternative strategies for toxicity testing of species-specific biopharmaceuticals.
Jeanine L Bussiere, Pauline Martin, Michelle Horner, Jessica Couch, Meghan Flaherty

Int J Toxicol· August 2009

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An investigation of hemopexin redox properties by spectroelectrochemistry: biological relevance for heme uptake.
Meghan M Flaherty, Kimberley R Rish, Ann Smith, Alvin L Crumbliss

Biometals· June 2008

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Depleted and natural uranium: chemistry and toxicological effects.
Elena Craft, Aquel Abu-Qare, Meghan Flaherty, Melissa Garofolo, Heather Rincavage

J Toxicol Environ Health B Crit Rev· July 2004

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Heterogeneity of toxicant response: sources of human variability.
Justin E Aldridge, Jennifer A Gibbons, Meghan M Flaherty, Marisa L Kreider, Jocelyn A Romano

Toxicol Sci· November 2003

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Synthesis and in vitro antioxidant properties of manganese(III) beta-octabromo-meso-tetrakis(4-carboxyphenyl)porphyrin.
Remy Kachadourian, Meghan M Flaherty, Alvin L Crumbliss, Manisha Patel, Brian J Day

J Inorg Biochem· July 2003

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