Publications by authors named "Mei-Lin Tang"

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Discovery of Novel Selective Estrogen Receptor β (SERβ) Agonist ()-STO021 as an Antiosteoporosis Candidate with Dual Functions of Inhibiting Osteoclastogenesis and Activating Osteoblastogenesis.
Cheng Peng, Zixiang Geng, Zhe Jiang, Jin-Feng Ning, Nan Wang, Mei-Lin Tang

J Med Chem· November 2025

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Discovery of a deuterated TNF-α small molecule modulator for potential treatment of ulcerative colitis.
Tong Song, Mengxiao Zhuang, Zhi Ying Dorothy Wong, Ge Xu, Mei-Lin Tang

Eur J Med Chem· July 2025

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From Hit to Lead: Discovery of First-In-Class Furanone Glycoside D228 Derived from for the Treatment of Inflammatory Bowel Disease.
Mei-Lin Tang, Xiao-Yu Xiong, Heyanhao Zhang, Yun-Zhi Wang, Rong-Qian Cheng

J Med Chem· October 2024

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Discovery of novel tubulin CBSI from the indanone scaffold for the treatment of colorectal cancer.
Zhipeng Huo, Delin Min, Shijie Zhang, Mei-Lin Tang, Xun Sun

RSC Med Chem· December 2023

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Discovery of First-in-Class TAK1-MKK3 Protein-Protein Interaction (PPI) Inhibitor for the Treatment of Ulcerative Colitis through Modulating TNF-α Production.
Mei-Lin Tang, Haidong Li, Jin-Feng Ning, Xiaoyan Shen, Xun Sun

J Med Chem· May 2022

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Discovery of Pyridone-Substituted Triazolopyrimidine Dual A/A AR Antagonists for the Treatment of Ischemic Stroke.
Mei-Lin Tang, Zi-Hao Wen, Jing-Huan Wang, Mei-Ling Wang, Heyanhao Zhang

ACS Med Chem Lett· March 2022

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Exosomes Derived from Hydroquinone-transformed Human Bronchial Epithelial Cells Inhibited Recipient Cell Apoptosis by transferring miR-221.
Hong Yi Xian, Ying Chen, Jia Ying Zhang, Mei Lin Tang, Zhen Wei Lian

Biomed Environ Sci· July 2021

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Discovery of Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) and Histone Deacetylase 1 (HDAC1) Dual Inhibitors Derived from the Natural Product Saprorthoquinone.
Yang Lin, Heyanhao Zhang, Tong Niu, Mei-Lin Tang, Jun Chang

Molecules· September 2020

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Novel octapeptide-DTX prodrugs targeting MMP-7 as effective agents for the treatment of colorectal cancer with lower systemic toxicity.
Zheng-Yu Liu, Mei-Lin Tang, Jin-Feng Ning, Yun-Peng Hao, Lu Zhou

Eur J Med Chem· May 2020

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A Concise Approach to -Substituted Rhodanines through a Base-Assisted One-Pot Coupling and Cyclization Process.
Yongxi Liang, Mei-Lin Tang, Zhipeng Huo, Chenchen Zhang, Xun Sun

Molecules· March 2020

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Novel Mercapto Propionamide Derivatives with Potent New Delhi Metallo-β-Lactamase-1 Inhibitory Activity and Low Toxicity.
Zhi Meng, Mei-Lin Tang, Liting Yu, Yongxi Liang, Jilai Han

ACS Infect Dis· June 2019

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Zinc-Mediated Decarboxylative Alkylation of Gem-difluoroalkenes.
Liting Yu, Mei-Lin Tang, Chang-Mei Si, Zhi Meng, Yongxi Liang

Org Lett· August 2018

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Sulfoxide-Based Enantioselective Nazarov Cyclization: Divergent Syntheses of (+)-Isopaucifloral F, (+)-Quadrangularin A, and (+)-Pallidol.
Mei-Lin Tang, Peng Peng, Zheng-Yu Liu, Jian Zhang, Jian-Ming Yu

Chemistry· October 2016

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Discovery of novel sesquistilbene indanone analogues as potent anti-inflammatory agents.
Mei-Lin Tang, Chen Zhong, Zheng-Yu Liu, Peng Peng, Xin-Hua Liu

Eur J Med Chem· May 2016

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Differential metabolism of 3FDT and docetaxel in RLMs, rats, and HLMs.
Mei-Lin Tang, Lu Zhou, Jun Chang, Zhuo-Han Hu, Yan Qin

Eur J Med Chem· May 2016

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