Publications by authors named "Meike Michaelsen"

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Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
Henrick Riemenschneider, Francesca Simonetti, Udit Sheth, Eszter Katona, Stefan Roth, Meike Michaelsen

Acta Neuropathol Commun· July 2023

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Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
Katherine D LaClair, Qihui Zhou, Meike Michaelsen, Benedikt Wefers, Monika S Brill

Acta Neuropathol· August 2020

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Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
Bahram Khosravi, Kathrine D LaClair, Henrick Riemenschneider, Qihui Zhou, Frédéric Frottin, Meike Michaelsen

EMBO J· April 2020

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Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model.
Qihui Zhou, Nikola Mareljic, Meike Michaelsen, Samira Parhizkar, Steffanie Heindl

EMBO Mol Med· February 2020

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Proteomics and neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity.
Hannelore Hartmann, Daniel Hornburg, Mareike Czuppa, Jakob Bader, Meike Michaelsen

Life Sci Alliance· May 2018

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Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.
Martin H Schludi, Lore Becker, Lillian Garrett, Tania F Gendron, Qihui Zhou, Meike Michaelsen

Acta Neuropathol· August 2017

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Antibodies inhibit transmission and aggregation of poly-GA dipeptide repeat proteins.
Qihui Zhou, Carina Lehmer, Meike Michaelsen, Kohji Mori, Dominik Alterauge

EMBO Mol Med· May 2017

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Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
Bahram Khosravi, Hannelore Hartmann, Stephanie May, Christoph Möhl, Helena Ederle, Meike Michaelsen

Hum Mol Genet· February 2017

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TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
Benjamin M Schwenk, Hannelore Hartmann, Alperen Serdaroglu, Martin H Schludi, Daniel Hornburg, Meike Michaelsen

EMBO J· November 2016

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