Publications by authors named "Melisa Saye"

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The potential of the antifungal nystatin to be repurposed to fight the protozoan .
Belén Jesús Maciel, Chantal Reigada, Fabio Augusto Digirolamo, Marcos Rengifo, Claudio Alejandro Pereira

Front Microbiol· March 2025

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Identifying inhibitors of Trypanosoma cruzi nucleoside diphosphate kinase 1 as potential repurposed drugs for Chagas' disease.
Facundo Galceran, Fabio A Digirolamo, Marcos Rengifo, Chantal Reigada, Melisa Saye

Biochem Pharmacol· October 2023

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Synthetic Activity of Recombinant Whole Cell Biocatalysts Containing 2-Deoxy-D-ribose-5-phosphate Aldolase from Pectobacterium atrosepticum.
Romina Fernández Varela, Ana Laura Valino, Eman Abdelraheem, Rosario Médici, Melisa Sayé

Chembiochem· July 2022

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Trypanocidal activity of the anthocyanidin delphinidin, a non-competitive inhibitor of arginine kinase.
Edward Valera-Vera, Chantal Reigada, Melisa Sayé, Fabio A Digirolamo, Facundo Galceran

Nat Prod Res· June 2022

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Revisiting trypanosomatid nucleoside diphosphate kinases.
Mariana R Miranda, Melisa Sayé, Chantal Reigada, Facundo Galceran, Marcos Rengifo

Mem Inst Oswaldo Cruz· February 2022

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Effect of capsaicin on the protozoan parasite Trypanosoma cruzi.
Edward A Valera-Vera, Chantal Reigada, Melisa Sayé, Fabio A Digirolamo, Facundo Galceran

FEMS Microbiol Lett· December 2020

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Expanding the scope of synthetic 1,2,4-trioxanes towards Trypanosoma cruzi and Leishmania donovani.
Noelia S Medrán, Melisa Sayé, Claudio A Pereira, Babu L Tekwani, Agustina La-Venia

Bioorg Med Chem Lett· October 2020

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Role of Trypanosoma cruzi nucleoside diphosphate kinase 1 in DNA damage responses.
Chantal Reigada, Melisa Sayé, Fabio Di Girolamo, Edward A Valera-Vera, Claudio A Pereira

Mem Inst Oswaldo Cruz· July 2020

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Computational approaches for drug discovery against trypanosomatid-caused diseases.
Claudio A Pereira, Melisa Sayé, Chantal Reigada, Ariel M Silber, Guillermo R Labadie

Parasitology· May 2020

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In silico repositioning of etidronate as a potential inhibitor of the Trypanosoma cruzi enolase.
Edward A Valera-Vera, Melisa Sayé, Chantal Reigada, Mariana R Miranda, Claudio A Pereira

J Mol Graph Model· March 2020

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Chagas Disease Treatment: From New Therapeutic Targets to Drug Discovery and Repositioning.
Mariana R Miranda, Melisa M Sayé

Curr Med Chem· January 2020

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Crystal violet structural analogues identified by in silico drug repositioning present anti-Trypanosoma cruzi activity through inhibition of proline transporter TcAAAP069.
Melisa Sayé, Lucrecia Gauna, Edward Valera-Vera, Chantal Reigada, Mariana R Miranda

PLoS Negl Trop Dis· January 2020

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Amino Acid and Polyamine Membrane Transporters in Trypanosoma cruzi: Biological Function and Evaluation as Drug Targets.
Melisa Sayé, Chantal Reigada, Lucrecia Gauna, Edward A Valera-Vera, Claudio A Pereira

Curr Med Chem· December 2019

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Identification of Polyamine Transport Inhibitors by Computational Drug Repurposing.
Chantal Reigada, Melisa Sayé, Otto Phanstiel, Edward Valera-Vera, Mariana R Miranda

Front Med (Lausanne)· November 2019

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Repurposing of terconazole as an anti agent.
Chantal Reigada, Melisa Sayé, Edward Valera-Vera, Mariana R Miranda, Claudio A Pereira

Heliyon· June 2019

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Techniques Used for Functional Characterization of Polyamine Transporters.
Claudio A Pereira, Melisa Sayé, Chantal Reigada, Mariana R Miranda

Methods Mol Biol· June 2018

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Evaluation of proline analogs as trypanocidal agents through the inhibition of a Trypanosoma cruzi proline transporter.
Melisa Sayé, Lucía Fargnoli, Chantal Reigada, Guillermo R Labadie, Claudio A Pereira

Biochim Biophys Acta Gen Subj· November 2017

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Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi.
Chantal Reigada, Edward A Valera-Vera, Melisa Sayé, Andrea E Errasti, Carla C Avila

PLoS Negl Trop Dis· March 2017

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A novel stage-specific glycosomal nucleoside diphosphate kinase from Trypanosoma cruzi.
Maria de Los Milagros Camara, Leon Bouvier, Chantal Reigada, Fabio A Digirolamo, Melisa Saye

Folia Parasitol· February 2017

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Trypanosoma cruzi Polyamine Transporter: Its Role on Parasite Growth and Survival Under Stress Conditions.
Chantal Reigada, Melisa Sayé, Edward Valera Vera, Darío Balcazar, Laura Fraccaroli

J Membr Biol· August 2016

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Trypanosoma cruzi Proline Transport Presents a Cell Density-dependent Regulation.
Melisa Sayé, Mariana R Miranda, Chantal Reigada, Claudio A Pereira

J Eukaryot Microbiol· July 2016

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Resveratrol inhibits Trypanosoma cruzi arginine kinase and exerts a trypanocidal activity.
Edward A Valera Vera, Melisa Sayé, Chantal Reigada, Flávia S Damasceno, Ariel M Silber

Int J Biol Macromol· June 2016

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Phytomonas: A non-pathogenic trypanosomatid model for functional expression of proteins.
Mariana R Miranda, Melisa Sayé, Chantal Reigada, Carolina Carrillo, Claudio A Pereira

Protein Expr Purif· October 2015

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Proline modulates the Trypanosoma cruzi resistance to reactive oxygen species and drugs through a novel D, L-proline transporter.
Melisa Sayé, Mariana R Miranda, Fabio di Girolamo, María de los Milagros Cámara, Claudio A Pereira

PLoS One· November 2014

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Cytosolic Trypanosoma cruzi nucleoside diphosphate kinase generates large granules that depend on its quaternary structure.
Claudio A Pereira, Chantal Reigada, Melisa Sayé, Fabio A Digirolamo, Mariana R Miranda

Exp Parasitol· July 2014

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