Publications by authors named "Melissa D Conrad"

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Efficacies of artemether-lumefantrine, artesunate-amodiaquine, dihydroartemisinin-piperaquine, and artesunate-pyronaridine for the treatment of uncomplicated Plasmodium falciparum malaria in children aged 6 months to 10 years in Uganda: a randomised, open-label, phase 4 clinical trial.
Moses R Kamya, Joaniter I Nankabirwa, Chris Ebong, Victor Asua, Moses Kiggundu, Melissa D Conrad

Lancet Infect Dis· January 2026

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Toward Setting Minimum and Optimal Data to Report for Malaria Molecular Surveillance with Targeted Sequencing: The "What" and "Why".
Jonathan J Juliano, Cecile P G Meier-Scherling, Neeva Wernsman Young, George A Tollefson, Sean V Connelly, Melissa D Conrad

Am J Trop Med Hyg· September 2025

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A novel locus associated with decreased susceptibility of Plasmodium falciparum to lumefantrine and dihydroartemisinin has emerged and spread in Uganda.
Karamoko Niare, Bersabeh Tafesse, Mayland Treat, Jacob Sadler, Martin Okitwi, Melissa D Conrad

bioRxiv· August 2025

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Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019-2024.
Martin Okitwi, Stephen Orena, Patrick K Tumwebaze, Thomas Katairo, Yoweri Taremwa, Melissa D Conrad

Nat Commun· August 2025

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Gametocyte production and transmission fitness of African and Asian isolates with differential susceptibility to artemisinins.
Nicholas I Proellochs, Chiara Andolina, Jordache Ramjith, Rianne Stoter, Geert-Jan van Gemert, Melissa D Conrad

Antimicrob Agents Chemother· June 2025

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Performance of molecular inversion probe DR23K and Paragon MADHatTeR Amplicon sequencing panels for detection of Plasmodium falciparum mutations associated with antimalarial drug resistance.
Thomas Katairo, Victor Asua, Bienvenu Nsengimaana, Stephen Tukwasibwe, Francis D Semakuba, Melissa D Conrad

Malar J· June 2025

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Significant variations in tolerance to clothianidin and pirimiphos-methyl in Anopheles gambiae and Anopheles funestus populations during a dramatic malaria resurgence despite sustained indoor residual spraying in Uganda.
Ambrose Oruni, Emmanuel Arinaitwe, James Adiga, Geoffrey Otto, Patrick Kyagamba, Melissa D Conrad

Parasit Vectors· June 2025

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Highly multiplexed molecular inversion probe panel in targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness.
Karamoko Niaré, Rebecca Crudale, Abebe A Fola, Neeva Wernsman Young, Victor Asua, Melissa D Conrad

Front Genet· June 2025

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Selection of Plasmodium falciparum kelch13 mutations in Uganda in comparison with southeast Asia: a modelling study.
Cecile P G Meier-Scherling, Oliver J Watson, Victor Asua, Isaac Ghinai, Thomas Katairo, Melissa D Conrad

Lancet Microbe· May 2025

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Field evaluation of the Bioline Malaria Ag P.f/Pan rapid diagnostic test: causes of microscopy discordance and performance in Uganda.
Kisakye Diana Kabbale, Bienvenu Nsengimaana, Francis D Semakuba, Brian A Kagurusi, Caroline Mwubaha, Melissa D Conrad

Malar J· May 2025

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Slowing the spread of treatment failure to artemisinin-based combination therapies in Uganda.
Tran Dang Nguyen, Robert J Zupko, Melissa D Conrad, Gerald B Rukundo, Carter C Farinha

medRxiv· May 2025

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Gametocyte production and transmission fitness of African and Asian isolates with differential susceptibility to artemisinins.
Nicholas I Proellochs, Chiara Andolina, Jordache Ramjith, Rianne Stoter, Geert-Jan van Gemert, Melissa D Conrad

bioRxiv· March 2025

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Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health.
Andrés Aranda-Díaz, Eric Neubauer Vickers, Kathryn Murie, Brian Palmer, Nicholas Hathaway, Melissa D Conrad

Sci Rep· March 2025

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Significant variations in tolerance to clothianidin and pirimiphos-methyl in and populations during a dramatic malaria resurgence despite sustained indoor residual spraying in Uganda.
Ambrose Oruni, Emmanuel Arinaitwe, James Adiga, Geoffrey Otto, Patrick Kyagamba, Melissa D Conrad

bioRxiv· February 2025

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Field evaluation of the Bioline Malaria Ag P.f/Pan Rapid Diagnostic Test: Causes of Microscopy Discordance and Performance in Uganda.
Kisakye Diana Kabbale, Bienvenu Nsengimaana, Francis D Semakuba, Brian A Kagurusi, Caroline Mwubaha, Melissa D Conrad

Res Sq· February 2025

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Changes in susceptibility of to antimalarial drugs in Uganda over time: 2019-2024.
Martin Okitwi, Stephen Orena, Patrick K Tumwebaze, Thomas Katairo, Yoweri Taremwa, Melissa D Conrad

medRxiv· January 2025

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Performance of Molecular Inversion Probe DR23K and Paragon MAD4HatTeR Amplicon Sequencing Panels for Detection of Plasmodium falciparum Mutations Associated with Antimalarial Drug Resistance.
Thomas Katairo, Victor Asua, Bienvenu Nsengimaana, Stephen Tukwasibwe, Francis D Semakuba, Melissa D Conrad

Res Sq· January 2025

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The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh isolates.
Martin Okitwi, Douglas A Shoue, Lisa A Checkley, Stephen Orena, Frida G Ceja, Melissa D Conrad

Antimicrob Agents Chemother· December 2024

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The emergence of artemisinin partial resistance in Africa: how do we respond?
Philip J Rosenthal, Victor Asua, Jeffrey A Bailey, Melissa D Conrad, Deus S Ishengoma

Lancet Infect Dis· September 2024

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susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan isolates.
Oriana Kreutzfeld, Stephen Orena, Martin Okitwi, Patrick K Tumwebaze, Oswald Byaruhanga, Melissa D Conrad

Antimicrob Agents Chemother· September 2024

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Varied Prevalence of Antimalarial Drug Resistance Markers in Different Populations of Newly Arrived Refugees in Uganda.
Stephen Tukwasibwe, Shreeya Garg, Thomas Katairo, Victor Asua, Brian A Kagurusi, Melissa D Conrad

J Infect Dis· August 2024

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Urgent action is needed to confront artemisinin partial resistance in African malaria parasites.
Deus S Ishengoma, Roly Gosling, Rosario Martinez-Vega, Khalid B Beshir, Jeffrey A Bailey, Melissa D Conrad

Nat Med· July 2024

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Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa.
Philip J Rosenthal, Victor Asua, Melissa D Conrad

Nat Rev Microbiol· June 2024

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Author Correction: Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa.
Philip J Rosenthal, Victor Asua, Melissa D Conrad

Nat Rev Microbiol· June 2024

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drug susceptibility and resistance mediating genetic polymorphisms of in Bobo-Dioulasso, Burkina Faso.
A Fabrice Somé, Melissa D Conrad, Zachari Kabré, Aminata Fofana, R Serge Yerbanga

Antimicrob Agents Chemother· April 2024

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