Publications by authors named "Melissa Edler"

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For All the Primate FANS: Optimized Isolation of Nuclei from Frozen Postmortem Primate Brain for Fluorescence-Assisted Nuclei Sorting (FANS).
Elaine E Guevara, Begün Erbaba, Gregory M Cresswell, Melissa K Edler, Chet C Sherwood

Yale J Biol Med· June 2025

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Amyloid-Beta, Tau, and Microglial Activation in Aged Felid Brains.
Veronika Kulik, Melissa K Edler, Mary Ann Raghanti, Aminu Imam, Chet C Sherwood

J Comp Neurol· November 2024

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Hedonic eating, obesity, and addiction result from increased neuropeptide Y in the nucleus accumbens during human brain evolution.
Mary Ann Raghanti, Elaine N Miller, Danielle N Jones, Heather N Smith, Emily L Munger, Melissa K Edler

Proc Natl Acad Sci U S A· September 2023

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The association of astrogliosis and microglial activation with aging and Alzheimer's disease pathology in the chimpanzee brain.
Melissa K Edler, Emily L Munger, Hannah Maycon, William D Hopkins, Patrick R Hof

J Neurosci Res· June 2023

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Age differences in cortical thickness and their association with cognition in chimpanzee (Pan troglodytes).
William D Hopkins, Xiang Li, Neil Roberts, Michele M Mulholland, Chet C Sherwood, Melissa K Edler

Neurobiol Aging· June 2023

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Age, adrenal steroids, and cognitive functioning in captive chimpanzees ().
Rafaela S C Takeshita, Melissa K Edler, Richard S Meindl, Chet C Sherwood, William D Hopkins

PeerJ· January 2023

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Comparative analysis of astrocytes in the prefrontal cortex of primates: Insights into the evolution of human brain energetics.
Emily L Munger, Melissa K Edler, William D Hopkins, Patrick R Hof, Chet C Sherwood

J Comp Neurol· December 2022

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Pathophysiological studies of aging Slc39a14 knockout mice to assess the progression of manganese-induced dystonia-parkinsonism.
Alexander N Rodichkin, Melissa K Edler, Jennifer L McGlothan, Tomás R Guilarte

Neurotoxicology· December 2022

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Metabolic labeling unveils alterations in the turnover of HDL-associated proteins during diabetes progression in mice.
Prabodh Sadana, Melissa Edler, Mirjavid Aghayev, Andrea Arias-Alvarado, Emilie Cohn

Am J Physiol Endocrinol Metab· December 2022

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Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer's Disease Risk.
Aseel Eid, Isha Mhatre-Winters, Ferass M Sammoura, Melissa K Edler, Richard von Stein

Environ Health Perspect· August 2022

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Comparative neuropathology in aging primates: A perspective.
Carmen Freire-Cobo, Melissa K Edler, Merina Varghese, Emily Munger, Jessie Laffey

Am J Primatol· November 2021

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Behavioral and neurochemical studies of inherited manganese-induced dystonia-parkinsonism in Slc39a14-knockout mice.
Alexander N Rodichkin, Melissa K Edler, Jennifer L McGlothan, Tomás R Guilarte

Neurobiol Dis· October 2021

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Age, sex, and regional differences in scavenger receptor CD36 in the mouse brain: Potential relevance to cerebral amyloid angiopathy and Alzheimer's disease.
Melissa K Edler, Cooper T Johnson, Hashim S Ahmed, Jason R Richardson

J Comp Neurol· June 2021

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Microglia in Aging and Alzheimer's Disease: A Comparative Species Review.
Melissa K Edler, Isha Mhatre-Winters, Jason R Richardson

Cells· May 2021

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Neuron loss associated with age but not Alzheimer's disease pathology in the chimpanzee brain.
Melissa K Edler, Emily L Munger, Richard S Meindl, William D Hopkins, John J Ely

Philos Trans R Soc Lond B Biol Sci· November 2020

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Decreased density of cholinergic interneurons in striatal territories in Williams syndrome.
Kari L Hanson, Caroline H Lew, Branka Hrvoj-Mihic, Deion Cuevas, Demi M Z Greiner, Melissa K Edler

Brain Struct Funct· April 2020

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Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees.
Emily L Munger, Melissa K Edler, William D Hopkins, John J Ely, Joseph M Erwin

J Comp Neurol· May 2019

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Microglia changes associated to Alzheimer's disease pathology in aged chimpanzees.
Melissa K Edler, Chet C Sherwood, Richard S Meindl, Emily L Munger, William D Hopkins

J Comp Neurol· December 2018

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A neurochemical hypothesis for the origin of hominids.
Mary Ann Raghanti, Melissa K Edler, Alexa R Stephenson, Emily L Munger, Bob Jacobs

Proc Natl Acad Sci U S A· February 2018

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Alternative microglial activation is associated with cessation of progressive dopamine neuron loss in mice systemically administered lipopolysaccharide.
Eric E Beier, Matthew Neal, Gelerah Alam, Melissa Edler, Long-Jun Wu

Neurobiol Dis· December 2017

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Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease.
Melissa K Edler, Chet C Sherwood, Richard S Meindl, William D Hopkins, John J Ely

Neurobiol Aging· November 2017

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Molecular and cellular reorganization of neural circuits in the human lineage.
André M M Sousa, Ying Zhu, Mary Ann Raghanti, Robert R Kitchen, Marco Onorati, Melissa K Edler

Science· November 2017

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Single low doses of MPTP decrease tyrosine hydroxylase expression in the absence of overt neuron loss.
Gelareh Alam, Melissa Edler, Shelbie Burchfield, Jason R Richardson

Neurotoxicology· May 2017

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Cholinergic innervation of the basal ganglia in humans and other anthropoid primates.
Alexa R Stephenson, Melissa K Edler, Joseph M Erwin, Bob Jacobs, William D Hopkins

J Comp Neurol· February 2017

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Human-specific increase of dopaminergic innervation in a striatal region associated with speech and language: A comparative analysis of the primate basal ganglia.
Mary Ann Raghanti, Melissa K Edler, Alexa R Stephenson, Lakaléa J Wilson, William D Hopkins

J Comp Neurol· July 2016

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