Publications by authors named "Meng-Lay Lin"

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PPARδ Orchestrates a Prometastatic Metabolic Response to Microenvironmental Cues in Pancreatic Cancer.
Beatriz Parejo-Alonso, David Barneda, Sara Maria David Trabulo, Sarah Courtois, Sara Compte-Sancerni, Meng-Lay Lin

Cancer Res· September 2025

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Alterations of the composition and spatial organization of the microenvironment following non-dysplastic Barrett's esophagus through progression to cancer.
Meng-Lay Lin, John W Hickey, Adam Passman, Emanuela Carlotti, Shruthi Devkumar

bioRxiv· June 2025

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The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells.
Juan Carlos López-Gil, Susana García-Silva, Laura Ruiz-Cañas, Diego Navarro, Adrián Palencia-Campos, Meng-Lay Lin, Carolina de la Pinta

Gut· August 2024

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A Self-Assembled 3D Model Demonstrates How Stiffness Educates Tumor Cell Phenotypes and Therapy Resistance in Pancreatic Cancer.
Ying Liu, Babatunde O Okesola, David Osuna de la Peña, Weiqi Li, Meng-Lay Lin

Adv Healthc Mater· July 2024

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Hepatocytes undergo punctuated expansion dynamics from a periportal stem cell niche in normal human liver.
Adam M Passman, Magnus J Haughey, Emanuela Carlotti, Marc J Williams, Bianca Cereser, Meng-Lay Lin

J Hepatol· August 2023

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Clonal Transitions and Phenotypic Evolution in Barrett's Esophagus.
James A Evans, Emanuela Carlotti, Meng-Lay Lin, Richard J Hackett, Magnus J Haughey

Gastroenterology· April 2022

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Correction to: Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer.
Muhammad Asaduzzaman, Stephanie Constantinou, Haoxiang Min, John Gallon, Meng-Lay Lin, Selina Raguz

Breast Cancer Res Treat· January 2018

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Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer.
Muhammad Asaduzzaman, Stephanie Constantinou, Haoxiang Min, John Gallon, Meng-Lay Lin, Selina Raguz

Breast Cancer Res Treat· June 2017

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The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1.
Michele Cioffi, Sara M Trabulo, Mireia Vallespinos, Deepak Raj, Tony Bou Kheir, Meng-Lay Lin

Oncotarget· March 2017

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LRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner.
Holly B Kramer, Chun-Fui Lai, Hetal Patel, Manikandan Periyasamy, Meng-Lay Lin

Nucleic Acids Res· January 2016

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Expression profiling of nuclear receptors in breast cancer identifies TLX as a mediator of growth and invasion in triple-negative breast cancer.
Meng-Lay Lin, Hetal Patel, Judit Remenyi, Christopher R S Banerji, Chun-Fui Lai, Colin A Purdie

Oncotarget· August 2015

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Single-cell paired-end genome sequencing reveals structural variation per cell cycle.
Thierry Voet, Parveen Kumar, Peter Van Loo, Susanna L Cooke, John Marshall, Meng-Lay Lin

Nucleic Acids Res· July 2013

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Meander: visually exploring the structural variome using space-filling curves.
Georgios A Pavlopoulos, Parveen Kumar, Alejandro Sifrim, Ryo Sakai, Meng Lay Lin

Nucleic Acids Res· June 2013

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Massive genomic rearrangement acquired in a single catastrophic event during cancer development.
Philip J Stephens, Chris D Greenman, Beiyuan Fu, Fengtang Yang, Graham R Bignell, Meng-Lay Lin

Cell· January 2011

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Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.
Ignacio Varela, Patrick Tarpey, Keiran Raine, Dachuan Huang, Choon Kiat Ong, Meng-Lay Lin

Nature· January 2011

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The patterns and dynamics of genomic instability in metastatic pancreatic cancer.
Peter J Campbell, Shinichi Yachida, Laura J Mudie, Philip J Stephens, Erin D Pleasance, Meng-Lay Lin

Nature· October 2010

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A comprehensive catalogue of somatic mutations from a human cancer genome.
Erin D Pleasance, R Keira Cheetham, Philip J Stephens, David J McBride, Sean J Humphray, Meng-Lay Lin, Lina Chen

Nature· January 2010

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A small-cell lung cancer genome with complex signatures of tobacco exposure.
Erin D Pleasance, Philip J Stephens, Sarah O'Meara, David J McBride, Alison Meynert, Meng-Lay Lin, Lina Chen, Stephen F McLaughlin

Nature· January 2010

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Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes.
Gillian L Dalgliesh, Kyle Furge, Chris Greenman, Lina Chen, Graham Bignell, Meng-Lay Lin

Nature· January 2010

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Complex landscapes of somatic rearrangement in human breast cancer genomes.
Philip J Stephens, David J McBride, Meng-Lay Lin, Ignacio Varela, Erin D Pleasance

Nature· December 2009

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Involvement of RQCD1 overexpression, a novel cancer-testis antigen, in the Akt pathway in breast cancer cells.
Masahiko Ajiro, Toyomasa Katagiri, Koji Ueda, Hidewaki Nakagawa, Chikako Fukukawa, Meng-Lay Lin

Int J Oncol· October 2009

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Involvement of G-patch domain containing 2 overexpression in breast carcinogenesis.
Meng-Lay Lin, Chikako Fukukawa, Jae-Hyun Park, Kie Naito, Kyoko Kijima

Cancer Sci· August 2009

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Activation of an estrogen/estrogen receptor signaling by BIG3 through its inhibitory effect on nuclear transport of PHB2/REA in breast cancer.
Jung-Won Kim, Miki Akiyama, Jae-Hyun Park, Meng-Lay Lin, Arata Shimo

Cancer Sci· August 2009

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer.
Gijs van Haaften, Gillian L Dalgliesh, Helen Davies, Lina Chen, Graham Bignell, Meng-Lay Lin, V Peter Collins

Nat Genet· May 2009

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Involvement of kinesin family member 2C/mitotic centromere-associated kinesin overexpression in mammary carcinogenesis.
Arata Shimo, Chizu Tanikawa, Toshihiko Nishidate, Meng-Lay Lin, Koichi Matsuda

Cancer Sci· January 2008

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