Publications by authors named "Merav D Shmueli"

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Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance.
Reut Tzemach, Chamutal Gur, Truong San Phan, Eyal David, Mor Zada, Merav D Shmueli

Sci Immunol· June 2025

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Translation dysregulation in cancer as a source for targetable antigens.
Chen Weller, Osnat Bartok, Christopher S McGinnis, Heyilimu Palashati, Tian-Gen Chang, Merav D Shmueli

Cancer Cell· May 2025

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Cell-autonomous innate immunity by proteasome-derived defence peptides.
Karin Goldberg, Arseniy Lobov, Paola Antonello, Merav D Shmueli, Idan Yakir

Nature· March 2025

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The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC.
Aaron Javitt, Merav D Shmueli, Matthias P Kramer, Aleksandra A Kolodziejczyk, Ivan J Cohen

Nat Cancer· May 2023

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Large-Scale Immunopeptidome Analysis Reveals Recurrent Posttranslational Splicing of Cancer- and Immune-Associated Genes.
Ronen Levy, Tal Alter Regev, Wayne Paes, Nofar Gumpert, Sapir Cohen Shvefel, Merav D Shmueli

Mol Cell Proteomics· April 2023

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Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation.
Danping Zheng, Gayatree Mohapatra, Lara Kern, Yiming He, Merav D Shmueli

Nat Immunol· April 2023

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Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors.
Assaf Kacen, Aaron Javitt, Matthias P Kramer, David Morgenstern, Tomer Tsaban, Merav D Shmueli

Nat Biotechnol· February 2023

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The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130.
Stephan A Müller, Merav D Shmueli, Xiao Feng, Johanna Tüshaus, Neele Schumacher

Mol Neurodegener· February 2023

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Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration.
Ron Benyair, Sai Srinivas Panapakkam Giridharan, Pilar Rivero-Ríos, Junya Hasegawa, Emily Bristow, Merav D Shmueli

Autophagy Rep· January 2023

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Histone degradation by the proteasome regulates chromatin and cellular plasticity.
Merav D Shmueli, Daoud Sheban, Avital Eisenberg-Lerner, Yifat Merbl

FEBS J· June 2022

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Tumor-reactive antibodies evolve from non-binding and autoreactive precursors.
Roei D Mazor, Nachum Nathan, Amit Gilboa, Liat Stoler-Barak, Lihee Moss, Merav D Shmueli

Cell· March 2022

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SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity.
Daoud Sheban, Tom Shani, Roey Maor, Alejandro Aguilera-Castrejon, Nofar Mor, Merav D Shmueli

Mol Cell· January 2022

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Altered Protein Abundance and Localization Inferred from Sites of Alternative Modification by Ubiquitin and SUMO.
Adi Ulman, Tal Levin, Bareket Dassa, Aaron Javitt, Assaf Kacen, Merav D Shmueli

J Mol Biol· October 2021

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Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3.
Martina Pigoni, Hung-En Hsia, Jana Hartmann, Jasenka Rudan Njavro, Merav D Shmueli

EMBO J· August 2020

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Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.
Jasenka Rudan Njavro, Jakob Klotz, Bastian Dislich, Johanna Wanngren, Merav D Shmueli

FASEB J· February 2020

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Golgi organization is regulated by proteasomal degradation.
Avital Eisenberg-Lerner, Ron Benyair, Noa Hizkiahou, Neta Nudel, Roey Maor, Merav D Shmueli

Nat Commun· January 2020

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Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Alkmini A Papadopoulou, Stephan A Müller, Torben Mentrup, Merav D Shmueli, Johannes Niemeyer

EMBO Rep· May 2019

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Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.
Alkmini A Papadopoulou, Stephan A Müller, Torben Mentrup, Merav D Shmueli, Johannes Niemeyer

EMBO Rep· March 2019

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Arginine refolds, stabilizes, and restores function of mutant pVHL proteins in animal model of the VHL cancer syndrome.
Merav D Shmueli, Limor Levy-Kanfo, Esraa Haj, Alan R Schoenfeld, Ehud Gazit

Oncogene· February 2019

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Interplay between protein glycosylation pathways in Alzheimer's disease.
Moran Frenkel-Pinter, Merav Daniel Shmueli, Chen Raz, Michaela Yanku, Shai Zilberzwige

Sci Adv· September 2017

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Total proteome turbidity assay for tracking global protein aggregation in the natural cellular environment.
Merav D Shmueli, Noa Hizkiahou, Sivan Peled, Ehud Gazit, Daniel Segal

J Biol Methods· April 2017

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Computational and experimental characterization of dVHL establish a Drosophila model of VHL syndrome.
Merav D Shmueli, Lee Schnaider, Gal Herzog, Ehud Gazit, Daniel Segal

PLoS One· September 2015

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The Lys-Specific Molecular Tweezer, CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity.
Gal Herzog, Merav D Shmueli, Limor Levy, Liat Engel, Ehud Gazit

Biochemistry· June 2015

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Structural insights into the folding defects of oncogenic pVHL lead to correction of its function in vitro.
Merav D Shmueli, Lee Schnaider, Daniel Rosenblum, Gal Herzog, Ehud Gazit

PLoS One· February 2014

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Evaluating Drosophila p53 as a model system for studying cancer mutations.
Gal Herzog, Andreas C Joerger, Merav D Shmueli, Alan R Fersht, Ehud Gazit

J Biol Chem· December 2012

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