Publications by authors named "Mercedes Onaderra"

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Minimized natural versions of fungal ribotoxins show improved active site plasticity.
Moisés Maestro-López, Miriam Olombrada, Lucía García-Ortega, Daniel Serrano-González, Javier Lacadena

Arch Biochem Biophys· April 2017

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Fungal Ribotoxins: A Review of Potential Biotechnological Applications.
Miriam Olombrada, Rodrigo Lázaro-Gorines, Juan C López-Rodríguez, Álvaro Martínez-Del-Pozo, Mercedes Oñaderra

Toxins (Basel)· February 2017

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Involvement of loop 5 lysine residues and the N-terminal β-hairpin of the ribotoxin hirsutellin A on its insecticidal activity.
Miriam Olombrada, Lucía García-Ortega, Javier Lacadena, Mercedes Oñaderra, José G Gavilanes

Biol Chem· January 2016

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Response of osteoblasts and preosteoblasts to calcium deficient and Si substituted hydroxyapatites treated at different temperatures.
María Concepción Matesanz, Javier Linares, Mercedes Oñaderra, María José Feito, Francisco Javier Martínez-Vázquez

Colloids Surf B Biointerfaces· September 2015

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Preparation of an engineered safer immunotoxin against colon carcinoma based on the ribotoxin hirsutellin A.
Jaime Tomé-Amat, Elías Herrero-Galán, Mercedes Oñaderra, Álvaro Martínez-Del-Pozo, José G Gavilanes

FEBS J· June 2015

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Involvement of loops 2 and 3 of α-sarcin on its ribotoxic activity.
Carlos Castaño-Rodríguez, Miriam Olombrada, Angélica Partida-Hanon, Javier Lacadena, Mercedes Oñaderra

Toxicon· March 2015

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Early in vitro response of macrophages and T lymphocytes to nanocrystalline hydroxyapatites.
María Concepción Matesanz, María José Feito, Mercedes Oñaderra, Cecilia Ramírez-Santillán, Carmen da Casa

J Colloid Interface Sci· February 2014

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Hirsutellin A: A Paradigmatic Example of the Insecticidal Function of Fungal Ribotoxins.
Elías Herrero-Galán, Lucía García-Ortega, Miriam Olombrada, Javier Lacadena, Álvaro Martínez Del Pozo

Insects· July 2013

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Fungal extracellular ribotoxins as insecticidal agents.
Miriam Olombrada, Elías Herrero-Galán, Daniel Tello, Mercedes Oñaderra, José G Gavilanes

Insect Biochem Mol Biol· January 2013

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Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells.
Jaime Tomé-Amat, Aida Menéndez-Méndez, Lucía García-Ortega, Carl A Batt, Mercedes Oñaderra

FEBS J· September 2012

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Production and characterization of a colon cancer-specific immunotoxin based on the fungal ribotoxin α-sarcin.
Nelson Carreras-Sangrà, Jaime Tomé-Amat, Lucía García-Ortega, Carl A Batt, Mercedes Oñaderra

Protein Eng Des Sel· August 2012

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A non-cytotoxic but ribonucleolytically specific ribotoxin variant: implication of tryptophan residues in the cytotoxicity of hirsutellin A.
Elías Herrero-Galán, Lucía García-Ortega, Javier Lacadena, Álvaro Martínez-del-Pozo, Nieves Olmo

Biol Chem· May 2012

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Implication of an Asp residue in the ribonucleolytic activity of hirsutellin A reveals new electrostatic interactions at the active site of ribotoxins.
Elías Herrero-Galán, Lucía García-Ortega, Javier Lacadena, Alvaro Martínez-Del-Pozo, Nieves Olmo

Biochimie· February 2012

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Solution structure of hirsutellin A--new insights into the active site and interacting interfaces of ribotoxins.
Aldino Viegas, Elias Herrero-Galán, Mercedes Oñaderra, Anjos L Macedo, Marta Bruix

FEBS J· April 2009

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The insecticidal protein hirsutellin A from the mite fungal pathogen Hirsutella thompsonii is a ribotoxin.
Elías Herrero-Galán, Javier Lacadena, Alvaro Martínez del Pozo, Drion G Boucias, Nieves Olmo

Proteins· July 2008

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The therapeutic potential of fungal ribotoxins.
Nelson Carreras-Sangrà, Elisa Alvarez-García, Elías Herrero-Galán, Jaime Tomé, Javier Lacadena

Curr Pharm Biotechnol· June 2008

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Fungal ribotoxins: molecular dissection of a family of natural killers.
Javier Lacadena, Elisa Alvarez-García, Nelson Carreras-Sangrà, Elías Herrero-Galán, Jorge Alegre-Cebollada

FEMS Microbiol Rev· March 2007

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Silent mutations at the 5'-end of the cDNA of actinoporins from the sea anemone Stichodactyla helianthus allow their heterologous overproduction in Escherichia coli.
Jorge Alegre-Cebollada, Giorgia Clementi, Michela Cunietti, Christian Porres, Mercedes Oñaderra

J Biotechnol· January 2007

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Anomalous electrophoretic behavior of a very acidic protein: ribonuclease U2.
Lucía García-Ortega, Vivian De los Ríos, Antonio Martínez-Ruiz, Mercedes Oñaderra, Javier Lacadena

Electrophoresis· September 2005

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Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding.
Lucía Garciá-Ortega, Javier Lacadena, Mayte Villalba, Rosalía Rodríguez, Jesús F Crespo

FEBS J· May 2005

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Conserved asparagine residue 54 of alpha-sarcin plays a role in protein stability and enzyme activity.
Ansgar Siemer, Manuel Masip, Nelson Carreras, Lucía García-Ortega, Mercedes Oñaderra

Biol Chem· December 2004

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Phenotypic selection and characterization of randomly produced non-haemolytic mutants of the toxic sea anemone protein sticholysin II.
Jorge Alegre-Cebollada, Valle Lacadena, Mercedes Oñaderra, José M Mancheño, José G Gavilanes

FEBS Lett· September 2004

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Leucine 145 of the ribotoxin alpha-sarcin plays a key role for determining the specificity of the ribosome-inactivating activity of the protein.
Manuel Masip, Lucía García-Ortega, Nieves Olmo, Maria Flor García-Mayoral, José Manuel Pérez-Cañadillas

Protein Sci· January 2003

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The antifungal protein AFP of Aspergillus giganteus is an oligonucleotide/oligosaccharide binding (OB) fold-containing protein that produces condensation of DNA.
Alvaro Martinez Del Pozo, Valle Lacadena, Jose M Mancheno, Nieves Olmo, Mercedes Onaderra

J Biol Chem· November 2002

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Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.
Lucia Garcia-Ortega, Manuel Masip, José M Mancheño, Mercedes Oñaderra, M Antonia Lizarbe

J Biol Chem· May 2002

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