Publications by authors named "Mercy Otteng"

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Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model.
Christoph W Zapf, Jonathan D Bloom, Zhong Li, Russell G Dushin, Thomas Nittoli, Mercy Otteng

Bioorg Med Chem Lett· August 2011

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Macrocyclic lactams as potent Hsp90 inhibitors with excellent tumor exposure and extended biomarker activity.
Christoph W Zapf, Jonathan D Bloom, Jamie L McBean, Russell G Dushin, Thomas Nittoli, Mercy Otteng

Bioorg Med Chem Lett· June 2011

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Discovery of 4-(benzylaminomethylene)isoquinoline-1,3-(2H,4H)-diones and 4-[(pyridylmethyl)aminomethylene]isoquinoline-1,3-(2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4.
Hwei-Ru Tsou, Xiaoxiang Liu, Gary Birnberg, Joshua Kaplan, Mercy Otteng

J Med Chem· April 2009

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4-(Phenylaminomethylene)isoquinoline-1,3(2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4 (CDK4).
Hwei-Ru Tsou, Mercy Otteng, Tritin Tran, M Brawner Floyd, Marvin Reich

J Med Chem· June 2008

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