Publications by authors named "Meredith A Jackson"

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Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage.
Sean K Bedingfield, Juan M Colazo, Fang Yu, Danielle D Liu, Meredith A Jackson

Nat Biomed Eng· September 2021

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Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers.
Meredith A Jackson, Shrusti S Patel, Fang Yu, Matthew A Cottam, Evan B Glass

Biomaterials· January 2021

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DNA Polyplexes of a Phosphorylcholine-Based Zwitterionic Polymer for Gene Delivery.
Kandarp M Dave, Linjiang Han, Meredith A Jackson, Lindsay Kadlecik, Craig L Duvall

Pharm Res· August 2020

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Dual carrier-cargo hydrophobization and charge ratio optimization improve the systemic circulation and safety of zwitterionic nano-polyplexes.
Meredith A Jackson, Sean K Bedingfield, Fang Yu, Mitchell E Stokan, Rachel E Miles

Biomaterials· February 2019

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Gal8 Visualization of Endosome Disruption Predicts Carrier-Mediated Biologic Drug Intracellular Bioavailability.
Kameron V Kilchrist, Somtochukwu C Dimobi, Meredith A Jackson, Brian C Evans, Thomas A Werfel

ACS Nano· February 2019

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Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.
Thomas A Werfel, Shan Wang, Meredith A Jackson, Taylor E Kavanaugh, Meghan Morrison Joly

Cancer Res· April 2018

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Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing.
Samantha M Sarett, Thomas A Werfel, Linus Lee, Meredith A Jackson, Kameron V Kilchrist

Proc Natl Acad Sci U S A· August 2017

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Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo.
Thomas A Werfel, Meredith A Jackson, Taylor E Kavanaugh, Kellye C Kirkbride, Martina Miteva

J Control Release· June 2017

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Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol.
Meredith A Jackson, Thomas A Werfel, Elizabeth J Curvino, Fang Yu, Taylor E Kavanaugh, Ayisha N Jackson

ACS Nano· June 2017

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Changes in Optical Properties of Plasmonic Nanoparticles in Cellular Environments are Modulated by Nanoparticle PEGylation and Serum Conditions.
Allen L Chen, Meredith A Jackson, Adam Y Lin, Elizabeth R Figueroa, Ying S Hu

Nanoscale Res Lett· December 2016

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Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing.
Samantha M Sarett, Thomas A Werfel, Irene Chandra, Meredith A Jackson, Taylor E Kavanaugh

Biomaterials· August 2016

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Quantifying spectral changes experienced by plasmonic nanoparticles in a cellular environment to inform biomedical nanoparticle design.
Allen L Chen, Ying S Hu, Meredith A Jackson, Adam Y Lin, Joseph K Young

Nanoscale Res Lett· September 2014

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