Publications by authors named "Meredith D Hartley"

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Temporal Dynamics of CNS Cholesterol Esters Correlate with Demyelination and Remyelination.
Nishama De Silva Mohotti, Jenna M Williams, Rashmi Binjawadagi, Hiroko Kobayashi, Disni Dedunupitiya, Meredith D Hartley

ACS Chem Neurosci· December 2025

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Temporal dynamics of CNS cholesterol esters correlate with demyelination and remyelination.
Nishama De Silva Mohotti, Jenna M Williams, Rashmi Binjawadagi, Hiroko Kobayashi, Disni Dedunupitiya, Meredith D Hartley

bioRxiv· November 2025

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Reduced cholesterol alters the biophysical properties of repaired myelin.
Estephanie L Nottar Escobar, Nishama De Silva Mohotti, Mara Manolescu, Anika Radadiya, Prajnaparamita Dhar, Meredith D Hartley

Biochim Biophys Acta Mol Cell Biol Lipids· June 2025

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Characterizing oxidative stress induced by Aβ oligomers and the protective role of carnosine in primary mixed glia cultures.
Vincenzo Cardaci, Lucia Di Pietro, Matthew C Zupan, Jay Sibbitts, Anna Privitera, Meredith D Hartley

Free Radic Biol Med· March 2025

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Lipidomic Analysis Reveals Differences in the Extent of Remyelination in the Brain and Spinal Cord.
Nishama De Silva Mohotti, Hiroko Kobayashi, Jenna M Williams, Rashmi Binjawadagi, Michel P Evertsen, Meredith D Hartley

J Proteome Res· August 2024

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Lipidomic analysis reveals differences in the extent of remyelination in the brain and spinal cord.
Nishama De Silv Mohotti, Hiroko Kobayashi, Jenna M Williams, Rashmi Binjawadagi, Michel P Evertsen, Meredith D Hartley

bioRxiv· July 2023

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Pharmacological Complementation Remedies an Inborn Error of Lipid Metabolism.
Meredith D Hartley, Mitra D Shokat, Margaret J DeBell, Tania Banerji, Lisa L Kirkemo

Cell Chem Biol· May 2020

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Myelin repair stimulated by CNS-selective thyroid hormone action.
Meredith D Hartley, Tania Banerji, Ian J Tagge, Lisa L Kirkemo, Priya Chaudhary

JCI Insight· April 2019

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Sobetirome and its Amide Prodrug Sob-AM2 Exert Thyromimetic Actions in Mct8-Deficient Brain.
Soledad Bárez-López, Meredith D Hartley, Carmen Grijota-Martínez, Thomas S Scanlan, Ana Guadaño-Ferraz

Thyroid· September 2018

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A Thyroid Hormone-Based Strategy for Correcting the Biochemical Abnormality in X-Linked Adrenoleukodystrophy.
Meredith D Hartley, Lisa L Kirkemo, Tapasree Banerji, Thomas S Scanlan

Endocrinology· May 2017

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Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetration.
Skylar J Ferrara, J Matthew Meinig, Andrew T Placzek, Tapasree Banerji, Peter McTigue, Meredith D Hartley

Bioorg Med Chem· May 2017

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Sobetirome prodrug esters with enhanced blood-brain barrier permeability.
Andrew T Placzek, Skylar J Ferrara, Meredith D Hartley, Hannah S Sanford-Crane, J Matthew Meinig

Bioorg Med Chem· November 2016

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Remyelination and multiple sclerosis: therapeutic approaches and challenges.
Meredith D Hartley, Ghadah Altowaijri, Dennis Bourdette

Curr Neurol Neurosci Rep· October 2014

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Lipid bilayer nanodisc platform for investigating polyprenol-dependent enzyme interactions and activities.
Meredith D Hartley, Philipp E Schneggenburger, Barbara Imperiali

Proc Natl Acad Sci U S A· December 2013

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At the membrane frontier: a prospectus on the remarkable evolutionary conservation of polyprenols and polyprenyl-phosphates.
Meredith D Hartley, Barbara Imperiali

Arch Biochem Biophys· January 2012

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Biochemical characterization of the O-linked glycosylation pathway in Neisseria gonorrhoeae responsible for biosynthesis of protein glycans containing N,N'-diacetylbacillosamine.
Meredith D Hartley, Michael J Morrison, Finn Erik Aas, Bente Børud, Michael Koomey

Biochemistry· June 2011

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Genetic and molecular analyses reveal an evolutionary trajectory for glycan synthesis in a bacterial protein glycosylation system.
Bente Børud, Raimonda Viburiene, Meredith D Hartley, Berit Smestad Paulsen, Wolfgang Egge-Jacobsen

Proc Natl Acad Sci U S A· June 2011

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Chemoenzymatic synthesis of polyprenyl phosphates.
Meredith D Hartley, Angelyn Larkin, Barbara Imperiali

Bioorg Med Chem· May 2008

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