Publications by authors named "Meriel R Major"

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Targeting an Initiator Allergen Provides Durable and Expansive Protection against House Dust Mite Allergy.
Jihui Zhang, Jie Chen, Jonathan P Richardson, Nicola-Jane Francis-Newton, Pei F Lai, Meriel R Major

ACS Pharmacol Transl Sci· September 2022

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The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma.
Gary K Newton, Trevor R Perrior, Kerry Jenkins, Meriel R Major, Rebekah E Key

J Med Chem· November 2014

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Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors.
Elizabeth H Donahue, Lisa F Dawson, Esmeralda Valiente, Stuart Firth-Clark, Meriel R Major

BMC Microbiol· August 2014

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Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones.
Mathew P Leese, Fabrice L Jourdan, Meriel R Major, Wolfgang Dohle, Mark P Thomas

ChemMedChem· April 2014

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Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines.
Wolfgang Dohle, Mathew P Leese, Fabrice L Jourdan, Meriel R Major, Ruoli Bai

ChemMedChem· February 2014

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Tetrahydroisoquinolinone-based steroidomimetic and chimeric microtubule disruptors.
Mathew P Leese, Fabrice L Jourdan, Meriel R Major, Wolfgang Dohle, Ernest Hamel

ChemMedChem· January 2014

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