Publications by authors named "Mesut Eren"

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A null mutation in protects against biological aging in humans.
Sadiya S Khan, Sanjiv J Shah, Ekaterina Klyachko, Abigail S Baldridge, Mesut Eren, Aaron T Place, Abraham Aviv, Eli Puterman, Donald M Lloyd-Jones, Meadow Heiman

November 2017

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Plasminogen activator inhibitor 1 promotes aortic aging-like pathophysiology in humans and mice.
Alireza Khoddam, Anthony Kalousdian, Mesut Eren, Saul Soberanes, Andrew Decker

J Clin Invest· December 2025

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Pharmacological inhibition of plasminogen activator inhibitor-1 prevents memory deficits and reduces neuropathology in APP/PS1 mice.
Guadalupe Rodriguez, Mesut Eren, Isabel Haupfear, Kirsten L Viola, Erika N Cline

Psychopharmacology (Berl)· December 2023

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Cardiomyocyte PAI-1 influences the cardiac transcriptome and limits the extent of cardiac fibrosis in response to left ventricular pressure overload.
Asish K Ghosh, Anthony A Kalousdian, Meng Shang, Elizabeth Lux, Mesut Eren

Cell Signal· April 2023

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Assessment of Virological Contributions to COVID-19 Outcomes in a Longitudinal Cohort of Hospitalized Adults.
Lacy M Simons, Ramon Lorenzo-Redondo, Meg Gibson, Sarah L Kinch, Jacob P Vandervaart, Mesut Eren

Open Forum Infect Dis· March 2022

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Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM.
Asish K Ghosh, Saul Soberanes, Elizabeth Lux, Meng Shang, Raul Piseaux Aillon, Mesut Eren

Environ Pollut· October 2021

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Role of PAI-1 in hepatic steatosis and dyslipidemia.
Joshua A Levine, Carlota Oleaga, Mesut Eren, Ansel P Amaral, Meng Shang

Sci Rep· January 2021

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Effects of lisinopril treatment on the pathophysiology of PCOS and plasminogen activator inhibitor-1 concentrations in rats.
Bugra Coskun, Cihangir M Ercan, Cihan Togrul, Esra U Ozhamam, Bora Coskun, Mesut Eren

Reprod Biomed Online· September 2020

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PAI-1 contributes to homocysteine-induced cellular senescence.
Tianjiao Sun, Asish K Ghosh, Mesut Eren, Toshio Miyata, Douglas E Vaughan

Cell Signal· December 2019

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Acetyltransferase p300 inhibitor reverses hypertension-induced cardiac fibrosis.
Rahul Rai, Tianjiao Sun, Veronica Ramirez, Elizabeth Lux, Mesut Eren

J Cell Mol Med· April 2019

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TGF-β-induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche.
Takashi Yahata, Abd Aziz Ibrahim, Yukari Muguruma, Mesut Eren, Alexander M Shaffer

Blood· November 2017

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Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan.
Rahul Rai, Asish K Ghosh, Mesut Eren, Alexander R Mackie, Daniel C Levine

Cell Rep· November 2017

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PAI-1 is a critical regulator of FGF23 homeostasis.
Mesut Eren, Aaron T Place, Paul M Thomas, Panagiotis Flevaris, Toshio Miyata

Sci Adv· September 2017

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Plasminogen Activator Inhibitor-1 Is a Marker and a Mediator of Senescence.
Douglas E Vaughan, Rahul Rai, Sadiya S Khan, Mesut Eren, Asish K Ghosh

Arterioscler Thromb Vasc Biol· August 2017

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Plasminogen Activator Inhibitor Type I Controls Cardiomyocyte Transforming Growth Factor-β and Cardiac Fibrosis.
Panagiotis Flevaris, Sadiya S Khan, Mesut Eren, Adam J T Schuldt, Sanjiv J Shah

Circulation· August 2017

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Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis.
Seok-Jo Kim, Paul Cheresh, Mesut Eren, Renea P Jablonski, Anjana Yeldandi

Am J Physiol Lung Cell Mol Physiol· July 2017

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A small molecule inhibitor of PAI-1 protects against doxorubicin-induced cellular senescence.
Asish K Ghosh, Rahul Rai, Kitae E Park, Mesut Eren, Toshio Miyata

Oncotarget· November 2016

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ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model.
Amy M Archer, Rana Saber, Shawn Rose, Alexander Shaffer, Alexander V Misharin, Mesut Eren

J Transl Med· June 2016

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Nitric oxide prevents alveolar senescence and emphysema in a mouse model.
Amanda E Boe, Mesut Eren, Luisa Morales-Nebreda, Sheila B Murphy, G R Scott Budinger

PLoS One· January 2016

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Role of plasminogen activator inhibitor-1 in senescence and aging.
Mesut Eren, Amanda E Boe, Ekaterina A Klyachko, Douglas E Vaughan

Semin Thromb Hemost· September 2014

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Functionally stable plasminogen activator inhibitor-1 in a family with cardiovascular disease and vitiligo.
Mehmet Agirbasli, Mesut Eren, Songul Yasar, Kenan Delil, Fatih Goktay

J Thromb Thrombolysis· July 2014

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PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.
Mesut Eren, Amanda E Boe, Sheila B Murphy, Aaron T Place, Varun Nagpal

Proc Natl Acad Sci U S A· May 2014

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Plasminogen activator inhibitor-1 antagonist TM5441 attenuates Nω-nitro-L-arginine methyl ester-induced hypertension and vascular senescence.
Amanda E Boe, Mesut Eren, Sheila B Murphy, Christine E Kamide, Atsuhiko Ichimura

Circulation· November 2013

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A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis.
Shawn Rose, Mesut Eren, Sheila Murphy, Heng Zhang, Colby Shad Thaxton

Ann Rheum Dis· January 2013

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A plasminogen activator inhibitor-1 inhibitor reduces airway remodeling in a murine model of chronic asthma.
Sun H Lee, Mesut Eren, Douglas E Vaughan, Robert P Schleimer, Seong H Cho

Am J Respir Cell Mol Biol· June 2012

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