Publications by authors named "Michael A Helmrath"

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Is Appendiceal Cancer a Risk of Nonoperative Management of Pediatric Uncomplicated Appendicitis?
Alexa G Turpin, Lindsey Asti, Carley Lutz, Jacqueline M Saito, Grace Z Mak, Michael A Helmrath

J Surg Res· December 2025

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Autologous Organoid-T Cell Co-Culture Platform for Modeling of Immune-Mediated Drug-Induced Liver Injury.
Fadoua El Abdellaoui Soussi, Michael Brusilovsky, Emma Buck, W Clark Bacon, Sina Dadgar, Michael A Helmrath

Adv Sci (Weinh)· November 2025

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Promoting Human Intestinal Organoid Formation and Stimulation Using Piezoelectric Nanofiber Matrices.
Holly M Poling, Akaljot Singh, Supasek Kongsomros, Maulee Sheth, Maksym Krutko, Michael A Helmrath

Tissue Eng Part A· November 2025

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A shift in PKM2 oligomeric state instructs adipocyte inflammatory potential.
Michelle Sma Damen, Pablo C Alarcon, Calvin C Chan, Traci E Stankiewicz, Hak Chung, Michael A Helmrath

JCI Insight· November 2025

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Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids.
Yifei Miao, Nicole M Pek, Cheng Tan, Cheng Jiang, Zhiyun Yu, Michael A Helmrath

Cell· August 2025

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Integrating collecting systems in human kidney organoids through fusion of distal nephron to ureteric bud.
Min Shi, Brittney Crouse, Nambirajan Sundaram, Naomi Pode Shakked, Konrad Thorner, Michael A Helmrath

Cell Stem Cell· July 2025

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Thermal Annealing Enhances Piezoelectricity and Regenerative Potential of PVDF-TrFE Nanofiber Scaffolds.
Maksym Krutko, Holly M Poling, Maulee Sheth, Supasek Kongsomros, Andrew E Bryan, Michael A Helmrath

Adv Mater Technol· July 2025

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Functional mobility and pain are improved for 6 years after adolescent bariatric surgery.
Neil Thivalapill, Todd M Jenkins, Thomas H Inge, Changchun Xie, Anita P Courcoulas, Michael A Helmrath

Obesity (Silver Spring)· June 2025

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Engineering Large-Scale and Innervated Functional Human Gut for Transplantation.
Holly M Poling, Théo Noël, Akaljot Singh, Garrett W Fisher, Konrad Thorner, Michael A Helmrath

bioRxiv· May 2025

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Mesenchymal WNT2B is required for the development and function of the human intestine.
Akaljot Singh, Holly M Poling, Jennifer Foulke-Abel, Nambirajan Sundaram, Abid A Reza, Michael A Helmrath

bioRxiv· May 2025

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Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells.
Kentaro Tominaga, Daniel O Kechele, J Guillermo Sanchez, Simon Vales, Ingrid Jurickova, Michael A Helmrath

Cell Mol Gastroenterol Hepatol· April 2025

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Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature.
Charlie J Childs, Holly M Poling, Kevin Chen, Yu-Hwai Tsai, Angeline Wu, Michael A Helmrath

Cell Stem Cell· April 2025

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Eicosatetraynoic Acid Regulates Profibrotic Pathways in an Induced Pluripotent Stem Cell-Derived Macrophage-Human Intestinal Organoid Model of Crohn's Disease.
Ingrid Jurickova, Benjamin W Dreskin, Elizabeth Angerman, Erin Bonkowski, Jack Nguyen, Michael A Helmrath

J Crohns Colitis· February 2025

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Human pluripotent stem cell-derived organoids repair damaged bowel in vivo.
Holly M Poling, Nambirajan Sundaram, Garrett W Fisher, Akaljot Singh, Joseph R Shiley, Michael A Helmrath

Cell Stem Cell· October 2024

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Ten-Year Outcomes after Bariatric Surgery in Adolescents.
Justin R Ryder, Todd M Jenkins, Changchun Xie, Anita P Courcoulas, Carroll M Harmon, Michael A Helmrath

N Engl J Med· October 2024

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Mechanical stimulation promotes human intestinal villus morphogenesis .
Holly M Poling, Nicole Brown, James M Wells, Riccardo Barrile, Michael A Helmrath

Biophys Rev (Melville)· September 2024

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Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric bud.
Min Shi, Brittney Crouse, Nambirajan Sundaram, Naomi Pode Shakked, Lioba Ester, Michael A Helmrath

bioRxiv· September 2024

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Enhanced Piezoelectric Performance of PVDF-TrFE Nanofibers through Annealing for Tissue Engineering Applications.
Maksym Krutko, Holly M Poling, Andrew E Bryan, Manju Sharma, Akaljot Singh, Michael A Helmrath

bioRxiv· August 2024

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Promoting Human Intestinal Organoid Formation and Stimulation Using Piezoelectric Nanofiber Matrices.
Holly M Poling, Akaljot Singh, Maksym Krutko, Abid A Reza, Kalpana Srivastava, Michael A Helmrath

bioRxiv· June 2024

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Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids.
Yifei Miao, Cheng Tan, Nicole M Pek, Zhiyun Yu, Kentaro Iwasawa, Michael A Helmrath

bioRxiv· February 2024

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Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohn's Disease.
Ingrid Jurickova, Benjamin W Dreskin, Elizabeth Angerman, Erin Bonkowski, Kentaro Tominaga, Michael A Helmrath

bioRxiv· January 2024

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Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon.
Jorge O Múnera, Daniel O Kechele, Carine Bouffi, Na Qu, Ran Jing, Michael A Helmrath

Cell Stem Cell· November 2023

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In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice.
Carine Bouffi, Kathryn A Wikenheiser-Brokamp, Praneet Chaturvedi, Nambirajan Sundaram, Gillian R Goddard, Michael A Helmrath

Nat Biotechnol· June 2023

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Marijuana, e-cigarette, and tobacco product use in young adults who underwent pediatric bariatric surgery.
Meg H Zeller, Heather Strong, Jennifer Reiter-Purtill, Todd M Jenkins, James E Mitchell, Michael A Helmrath

Surg Obes Relat Dis· May 2023

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Transplanted human intestinal organoids: a resource for modeling human intestinal development.
Akaljot Singh, Holly M Poling, Praneet Chaturvedi, Konrad Thorner, Nambirajan Sundaram, Michael A Helmrath

Development· May 2023

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