Publications by authors named "Michael A Mastrangelo"

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The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function.
J Allen Bennett, Michael A Mastrangelo, Sara K Ture, Charles O Smith, Shannon G Loelius

Nat Commun· July 2020

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Acetylcholine Inhibits Platelet Activation.
John A Bennett, Sara K Ture, Rachel A Schmidt, Michael A Mastrangelo, Scott J Cameron

J Pharmacol Exp Ther· May 2019

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Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.
Maria Sabater-Lleal, Jennifer E Huffman, Paul S de Vries, Jonathan Marten, Michael A Mastrangelo

Circulation· January 2019

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Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis.
Racquel Domingo-Gonzalez, Shibali Das, Kristin L Griffiths, Mushtaq Ahmed, Monika Bambouskova, Michael A Mastrangelo

JCI Insight· October 2017

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Novel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice.
Qiuyu Martin Zhu, Kyung Ae Ko, Sara Ture, Michael A Mastrangelo, Ming-Huei Chen

Arterioscler Thromb Vasc Biol· February 2017

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SIRT6 protects against endothelial dysfunction and atherosclerosis in mice.
Suowen Xu, Meimei Yin, Marina Koroleva, Michael A Mastrangelo, Wenbo Zhang

Aging (Albany NY)· May 2016

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Chronic neuron- and age-selective down-regulation of TNF receptor expression in triple-transgenic Alzheimer disease mice leads to significant modulation of amyloid- and Tau-related pathologies.
Sara L Montgomery, Wade C Narrow, Michael A Mastrangelo, John A Olschowka, M Kerry O'Banion

Am J Pathol· June 2013

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Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease.
Jesse M Hunter, William J Bowers, Chera L Maarouf, Michael A Mastrangelo, Ian D Daugs

J Alzheimers Dis· August 2012

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Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain.
Sara L Montgomery, Michael A Mastrangelo, Diala Habib, Wade C Narrow, Sara A Knowlden

Am J Pathol· October 2011

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Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivo.
Suresh de Silva, Michael A Mastrangelo, Louis T Lotta, Clark A Burris, Zsuzsanna Izsvák

Hum Gene Ther· November 2010

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Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target.
Maya K Desai, Michael A Mastrangelo, Deborah A Ryan, Kelly L Sudol, Wade C Narrow

Am J Pathol· September 2010

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Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice.
Deborah A Ryan, Michael A Mastrangelo, Wade C Narrow, Mark A Sullivan, Howard J Federoff

Mol Ther· August 2010

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Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease.
Kelly L Sudol, Michael A Mastrangelo, Wade C Narrow, Maria E Frazer, Yona R Levites

Mol Ther· December 2009

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Interferon-{gamma} differentially affects Alzheimer's disease pathologies and induces neurogenesis in triple transgenic-AD mice.
Michael A Mastrangelo, Kelly L Sudol, Wade C Narrow, William J Bowers

Am J Pathol· November 2009

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Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology.
Maya K Desai, Kelly L Sudol, Michelle C Janelsins, Michael A Mastrangelo, Maria E Frazer

Glia· January 2009

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Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD mice.
Michelle C Janelsins, Michael A Mastrangelo, Keigan M Park, Kelly L Sudol, Wade C Narrow

Am J Pathol· December 2008

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Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice.
Michael A Mastrangelo, William J Bowers

BMC Neurosci· August 2008

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Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4.
Maria E Frazer, Jennifer E Hughes, Michael A Mastrangelo, Jennifer L Tibbens, Howard J Federoff

Mol Ther· May 2008

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Reduced Pathology and Improved Behavioral Performance in Alzheimer's Disease Mice Vaccinated With HSV Amplicons Expressing Amyloid-β and Interleukin-4.
Maria E Frazer, Jennifer E Hughes, Michael A Mastrangelo, Jennifer L Tibbens, Howard J Federoff

Mol Ther· May 2008

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Neuronal specificity of HSV/sleeping beauty amplicon transduction in utero is driven primarily by tropism and cell type composition.
Elise B Peterson, Michael A Mastrangelo, Howard J Federoff, William J Bowers

Mol Ther· October 2007

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Neuronal precursor-restricted transduction via in utero CNS gene delivery of a novel bipartite HSV amplicon/transposase hybrid vector.
William J Bowers, Michael A Mastrangelo, Darlene F Howard, Hilary A Southerland, Kathleen A Maguire-Zeiss

Mol Ther· March 2006

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Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice.
Michelle C Janelsins, Michael A Mastrangelo, Salvatore Oddo, Frank M LaFerla, Howard J Federoff

J Neuroinflammation· October 2005

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HSV amplicon-mediated Abeta vaccination in Tg2576 mice: differential antigen-specific immune responses.
William J Bowers, Michael A Mastrangelo, Hilary A Stanley, Ann E Casey, Lawrence J Milo

Neurobiol Aging· April 2005

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Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS.
John A Olschowka, William J Bowers, Sean D Hurley, Michael A Mastrangelo, Howard J Federoff

Mol Ther· February 2003

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